Journal of the European Academy of Dermatology and Venereology




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Issue Information

doi : 10.1111/jdv.16659

Volume 35, Issue 11 p. 2109-2114

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Editor's Picks

doi : 10.1111/jdv.17691

Volume 35, Issue 11 p. 2115-2115

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30 years of JEADV – 30 years of progress in Dermatology and Venereology

J. Ring

doi : 10.1111/jdv.17670

Volume 35, Issue 11 p. 2116-2117

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JEADV – the birth

D. Freedman,T. Lotti

doi : 10.1111/jdv.17662

Volume 35, Issue 11 p. 2118-2120

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Thirty years of new entities in inflammatory dermatology and dermatopathology

F. Rongioletti

doi : 10.1111/jdv.17653

Volume 35, Issue 11 p. 2121-2122

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The changing landscape of managing hair loss: a 30-year perspective

L. Rudnicka

doi : 10.1111/jdv.17651

Volume 35, Issue 11 p. 2123-2124

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Ambassadors in Dermatology and Venereology: an interview with Doctor Hans W. Rothenborg

Hans W. Rothenborg

doi : 10.1111/jdv.17661

Volume 35, Issue 11 p. 2125-2127

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Treatment of keloids and hypertrophic scars. Position statement of the Brazilian expert group GREMCIQ

G.V. Oliveira,L.D. Metsavaht,B.V Kadunc,S.K.K. Jedwab,M.S. Bressan,H.O. Stolf,R.G. Castro,S.M.F.M.C. Bezerra,D.A. Calil,F.A.Z. Addor,J.C.S. Fraga,C.M.S. Reis,E. Reis-Filho,M.R. Silva,M. Ramos-e-Silva,D.M. Hexsel

doi : 10.1111/jdv.17484

Volume 35, Issue 11 p. 2128-2142

Keloids (K) and hypertrophic scars (HS) are abnormal responses to wound healing that occur as the result of dermal inflammation. Despite the advances on their treatment, many patients still suffer from the negative effects of excessive scarring; its approach is impaired by the lack of objective data on different treatments and the large genetic variability among patients and the difficulties in producing multicentre studies. Their incidence among the Brazilian population is high, as the result of an admixture of Amerindians, Europeans and Africans ancestral roots. With the aim of producing multicentre studies on K and HS, a panel of senior Brazilian dermatologists focused on their treatment was invited to contribute with the K and HS Treatment Brazilian Guidelines. In the first part of this study, different treatment modalities for keloids and HS are fully reviewed by the panel. The second part of the study presents a consensus recommendation of treatment for different types of lesions. More than a literature review, this article aims to show the pitfalls and pearls of each therapeutic option, as well as a therapeutic approach by the Panel of Experts on keloids and Scars on a highly mixed population, providing simple guidelines.

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Position statement on the role of nurses in therapeutic patient education in atopic dermatitis

K. Thormann,H. Aubert,S. Barbarot,A. Britsch-Yilmaz,P. Chernyshov,M. Deleuran,M. El-Hachem,J. de Groot,A. Heratizadeh,F. Raymakers,J.F. Stalder,A. Wollenberg,D. Simon

doi : 10.1111/jdv.17487

Volume 35, Issue 11 p. 2143-2148

In chronic skin diseases such as atopic dermatitis (AD), therapeutic failure due to poor patient adherence to treatment is commonly reported. Therapeutic patient education (TPE) is an approach to improve self-management and adherence. Several studies demonstrated that TPE programmes have positive effects on disease management resulting in decreased disease severity and improved quality of life in AD patients. Various healthcare professionals (dermatologists, nurses, psychologists, dieticians) have been involved. TPE performed by trained dermatology nurses are highly efficient and improve various health-related outcomes. The aim of this position paper is to analyse the aims, modalities and efficacy of TPE in AD, to identify specific roles of dermatology nurses, to assess qualification requirements, and to propose practical recommendations. Potential activities of nurses in ongoing and future TPE programmes for AD patients will be discussed.

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Position statement on classification of basal cell carcinomas. Part 2: EADO proposal for new operational staging system adapted to basal cell carcinomas

J.J. Grob,C. Gaudy-Marqueste,A. Guminski,J. Malvehy,N. Basset-seguin,B. Bertrand,P. Fernandez-Penas,R. Kaufmann,I. Zalaudek,M.C. Fargnoli,L. Tagliaferri,B. Fertil,V. Del Marmol,A. Stratigos,C. Garbe,K. Peris

doi : 10.1111/jdv.17467

Volume 35, Issue 11 p. 2149-2153

No simple staging system has emerged for basal cell carcinomas (BCCs), since they do not follow the TNM process, and practitioners failed to agree on simple clinical or pathological criteria as a basis for a classification. Operational classification of BCCs is required for decision-making, trials and guidelines. Unsupervised clustering of real cases of difficult-to-treat BCCs (DTT-BCCs; part 1) has demonstrated that experts could blindly agree on a five groups classification of DTT-BCCs based on five patterns of clinical situations.

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The effectiveness of educational programmes in promoting sun protection among children under the age of 18: a systematic review and meta-analysis

W.M.B. Sim,M.X. Zeng,A. Rojas-Garcia

doi : 10.1111/jdv.17599

Volume 35, Issue 11 p. 2154-2165

Childhood ultraviolet radiation exposure has a strong connection to the development of skin cancer in later life. Therefore, there have been numerous sun protection educational programmes targeted to this age group. However, the association between these have not been well established. This systematic review aims to summarize the evidence on, and assess, the effectiveness of educational programmes in improving sun protection among children under age-18. The protocol was prospectively registered in the PROSPERO database (CRD42020178264). Per PRISMA guidelines, bibliographic databases CENTRAL, OVID (EMBASE, MEDLINE, PsycINFO), LILACS, trial registries, grey literature and other sources were systematically searched for randomized controlled and clinical controlled trials published between database inception to 9 June 2020. Dual independent review of abstracts and full texts was performed. Eligible studies were assessed for methodological quality using the Cochrane risk-of-bias tool. The primary outcome was postintervention scores [standardized mean difference (SMD)] for sun protection (i) knowledge (ii) attitudes and beliefs (iii) behavioural intentions and behaviours. Sidik-Jonkman random effects meta-analysis, sensitivity and subgroup analyses were performed for specific outcomes (sunscreen and sun-safe hat use) which were sufficiently reported. 1350 publications were identified and 24 eligible trials, conducted across 8 different countries, with sufficient aggregate data were included. Small-to-moderate effects of educational programmes were observed across all sun protection outcomes of interest, but negligible effect sizes were demonstrated when specific outcomes were meta-analysed – sunscreen use, SMD 0.18 (95% CI 0.07–0.29; n = 8) and sun-safe hat use, SMD 0.08 (95% CI, 0.00–0.16; n = 6). A promising approach in the future may be to consider targeting children in secondary education with a digitally delivered interactive intervention. Current evidence, however, is insufficient to assess the effects of potential moderators and change in sun protection outcomes is likely not one-size-fits-all. Further research is warranted to direct intervention design and public policy.

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Mapping risk factors for cumulative life course impairment in patients with chronic skin diseases – a systematic review

C.C. von Stülpnagel,M. Augustin,L. Düpmann,N. da Silva,R. Sommer

doi : 10.1111/jdv.17348

Volume 35, Issue 11 p. 2166-2184

Patients with chronic skin diseases suffer from physical and psychosocial impairments which can lead to a cumulative life-long burden. Therefore, the concept of cumulative life course impairment (CLCI) was introduced, referring to the non-reversible damage due to the persistent life-long burden. This systematic review (PROSPERO registry number: CRD42020179141) aimed at mapping the risk factors and the associated burden over time in patients with psoriasis, atopic dermatitis (AD) and hidradenitis suppurativa (HS). Three electronic databases were searched (date of the last search: December 2019). Studies with a longitudinal study design that assessed the association between a risk factor and the associated burden over time in patients with psoriasis, AD and HS were included. Quality assessment of the included studies was done using Critical Appraisal Skills Programme (CASP) checklists. In total, 40 publications reflecting 25 different studies were included: nine studies addressed patients with psoriasis, 13 patients with AD, two studies included patients with HS and one study enrolled patients with psoriasis and AD, respectively. Twenty-two potential risk factors with underlying evidence were found in this review. These risk factors include mainly sociodemographic (such as age or gender) and clinical (such as disease severity or comorbidities) variables. Disease severity and comorbidities were the most often studied risk factors, while only a few studies evaluated psychosocial risk factors over time. Patients with chronic skin diseases are at high risk to develop a life-long negative impact from the disease. However, there is a lack of data that evaluates the psychosocial burden and its influence on the patients’ life course over time. The risk factors found in this review help to identify patients at risk, to treat them adequately and, ultimately, to prevent CLCI. These results can be the basis to develop a highly needed tool to assess the risk for CLCI in the future.

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Systematic review of single and combined treatments for different types of striae: a comparison of striae treatments

F. Seirafianpour,S. Sodagar,S. Mozafarpoor,H.R. Baradaran,P. Panahi,B. Hassanlouei,A. Goodarzi

doi : 10.1111/jdv.17374

Volume 35, Issue 11 p. 2185-2198

Striae distensae (SD) or stretch marks are among the most common forms of atrophic scarring and cosmetic problems, especially in women, that negatively affect quality of life. The main causes of SD vary widely, but the most significant ones include obesity, pregnancy, high corticosteroid levels, weight changes, endocrine disorders and genetic predispositions. Various modalities are available for the treatment of SD; however, there is still no gold standard therapy for this condition. Given the many questions concerning the preferred therapeutic modalities for SD or their overall cost-effectiveness, this comprehensive systematic review discusses the most prevalent, recent and promising therapies for SD in three main categories, including single therapy, therapeutic comparisons and combination therapy. A systematic search was carried out in Medline, Scopus, Web of Science and Google Scholar for original articles published on the treatment of SD by 20 May 2019. One hundred articles were reviewed and divided into three categories. In the single therapy category, we found that laser and other light-based devices and topical treatments are the most commonly applied interventions. In the therapeutic comparison category, we found that most of the common therapeutic modalities are equally effective and there is no significant difference between them in side-effects and treatment duration. In the combination therapy category, we found that the combination of two or more modalities is usually better than using each one alone.

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Tinea capitis asymptomatic carriers: what is the evidence behind treatment?

A. Aharaz,G.B.E. Jemec,R.J. Hay,D.M.L. Saunte

doi : 10.1111/jdv.17462

Volume 35, Issue 11 p. 2199-2207

Tinea capitis is a fungal infection mostly affecting children. Epidemiology is changing over time due to migration, and it has been estimated that up to 40% of children from certain developing countries are affected. The mechanism of transmission is still unclear although asymptomatic carriage seems to have an influence in establishing persistent reservoirs that can cause or fuel epidemics. Screening and prophylactic treatment of close contacts of tinea capitis patients are therefore recommended by several international guidelines, but vaguely and not consistent. The treatments involved can be expensive, hard to integrate in everyday life, have well-known side effects and some are not approved for the treatment of children. The aim of this review was to clarify the evidence behind treatment of human asymptomatic carriers of tinea capitis. Databases were searched for the ‘tinea capitis’, ‘carriers’ and ‘treatment’. Inclusion criteria were clinical trials, observational and interventional studies including case series (10+ cases) and case reports in English, Danish, Swedish, Norwegian and French. Reviews, guidelines, unclear reports and in vitro trials were excluded. A systematic review identified 10 studies with low to moderate evidence levels. The topical treatments ketoconazole, povidone-iodine, miconazole and the systemic antifungals terbinafine and itraconazole have all shown significant effects in the mycological eradication of fungal conidia. General prophylactic hygienic measures may have a benefit. The scientific evidence behind the treatment of asymptomatic carriage of scalp dermatophytes is sparse and not of high quality. Yet, both topical and systemic antifungal agents show treatment efficacy. Considering the possible adverse effects, topical agents are preferable, but with necessary attention to the compliance of asymptomatic contacts with treatment.

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Electrochemotherapy with bleomycin for basal cell carcinomas: a systematic review

K. Hendel,G. B. E. Jemec,M. Haedersdal,S. R. Wiegell

doi : 10.1111/jdv.17492

Volume 35, Issue 11 p. 2208-2215

Basal cell carcinoma (BCC) is the most common type of cancer and an increasing incidence stimulates the interest in new treatments such as electrochemotherapy (ECT) with bleomycin. This systematic review focuses on literature from the MEDLINE, Embase, Web of Science, and Cochrane databases. Bleomycin-ECT studies (n = 32) were sorted by the level of evidence adjusted for their BCC data only. The studies included a single randomised controlled trial (RCT), 15 uncontrolled clinical trials, three registry studies, six prospective case series and seven retrospective case series. A Cochrane risk-of-bias assessment of the RCT identified some minor concerns but no predicted risk of bias. The studies were also grouped by bleomycin administration routes: intravenous (n = 14), intralesional (n = 9) and mixed reporting/usage (n = 9). A meta-analysis was not conducted due to the lack of RCTs and the heterogeneity of the included studies. The results of the RCT generally reflected the findings of the other included studies and showed a 92% complete response in 65 bleomycin-ECT–treated BCCs after 2 months, improving to 100% after re-treatment, with a low risk of recurrence. Based on the RCT results and overall data, future studies on BCC treatment with bleomycin-ECT should include large RCTs that compare bleomycin-ECT with standard of care, cost analyses, and clinical feasibility.

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Ageing research: rethinking primary prevention of skin cancer

C. Posch

doi : 10.1111/jdv.17660

Volume 35, Issue 11 p. 2216-2218

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Concordance between a Mohs surgeon and a dermatopathologist in evaluating Mohs cryosections

S. Atilla,Ö. Gököz,S. Özer,G. Elçin

doi : 10.1111/jdv.17574

Volume 35, Issue 11 p. 2219-2224

Mohs micrographic surgery is the gold standard treatment for high-risk non-melanoma skin cancers. The success of Mohs relies on accurate histopathologic evaluation. Due to law restrictions in some European countries, Mohs surgeons are not permitted to report on histopathology; therefore, a pathologist evaluates the frozen sections.

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Efficacy and safety of mogamulizumab by patient baseline blood tumour burden: a post hoc analysis of the MAVORIC trial

R.A. Cowan,J.J. Scarisbrick,P.L. Zinzani,J.P. Nicolay,L. Sokol,L. Pinter-Brown,P. Quaglino,L. Iversen,R. Dummer,A. Musiek,F. Foss,T. Ito,J-P. Rosen,M.C. Medley

doi : 10.1111/jdv.17523

Volume 35, Issue 11 p. 2225-2238

Mogamulizumab was compared with vorinostat in the phase 3 MAVORIC trial (NCT01728805) in 372 patients with relapsed/refractory mycosis fungoides (MF) or Sézary syndrome (SS) who had failed ?1 prior systemic therapy. Mogamulizumab significantly prolonged progression-free survival (PFS), with a superior objective response rate (ORR) vs. vorinostat.

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The golden ages of inflammatory skin diseases: skyrocketing developments in the therapy of psoriasis and atopic dermatitis

L. Kemény

doi : 10.1111/jdv.17655

Volume 35, Issue 11 p. 2239-2240

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Secukinumab effects on disease burden, patient needs and benefits, and treatment satisfaction in patients with plaque psoriasis across European regions: patient perspective data from the PROSE study

N. da Silva,R. Sommer,C.-E. Ortmann,P. Jagiello,T. Bachhuber,M. Augustin

doi : 10.1111/jdv.17525

Volume 35, Issue 11 p. 2241-2249

Cross-cultural differences in healthcare policies and patient–physician communication may influence the quality of care and patients' perceived benefits and satisfaction with psoriasis treatment.

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The use of psoriasis biomarkers, including trajectory of clinical response, to predict clearance and remission duration to UVB phototherapy

N. Watson,N. Wilson,F. Shmarov,P. Zuliani,N.J. Reynolds,S.C. Weatherhead

doi : 10.1111/jdv.17519

Volume 35, Issue 11 p. 2250-2258

Remission duration and treatment response following phototherapy for psoriasis are highly variable and factors influencing these are poorly understood.

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Chronic urticaria – From ‘Cinderella’ to a ‘Rock star’ in 30 years

M. Gonçalo

doi : 10.1111/jdv.17659

Volume 35, Issue 11 p. 2259-2260

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Pruritus and prurigo: a significant advancement on diagnosis, classification, pathogenesis and treatment

A. Reich

doi : 10.1111/jdv.17664

Volume 35, Issue 11 p. 2261-2262

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Characteristics of children and adolescents with atopic dermatitis who attended therapeutic patient education

S. Barbarot,F. Boralevi,J. Shourick,F. Sampogna,E. Mahé,S. Merhand,A.-C. Bursztejn,S. Mallet,K. Ezzedine,C. Abasq,C. Taïeb,A. Lasek,C. Bodemer

doi : 10.1111/jdv.17526

Volume 35, Issue 11 p. 2263-2269

Atopic dermatitis (AD) is a chronic, relapsing, inflammatory skin disease. Therapeutic patient education (TPE) has been demonstrated to be effective in AD in reducing disease severity and improving coping and quality of life.

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Prevalence, incidence and presence of comorbidities in patients with prurigo and pruritus in Germany: A population-based claims data analysis

M. Augustin,C. Garbe,K. Hagenström,J. Petersen,M.P. Pereira,S. Ständer

doi : 10.1111/jdv.17485

Volume 35, Issue 11 p. 2270-2276

There are currently no published population-based data on prurigo and pruritus epidemiology in Germany.

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Improvement in Hidradenitis Suppurativa and quality of life in patients treated with adalimumab: Real-world results from the HARMONY Study

A. Hafner,P.D. Ghislain,R. Kovács,R. Batchelor,A.C. Katoulis,B. Kirby,H. Banayan,M. Schonbrun

doi : 10.1111/jdv.17551

Volume 35, Issue 11 p. 2277-2284

Hidradenitis suppurativa (HS), a chronic, recurrent, debilitating skin disease, is characterized by painful, inflammatory, subcutaneous lesions of the axilla, inguinal and anogenital regions. Overall prevalence of HS is ˜1%, and the impact of disease on patient quality of life (QoL) and healthcare resource utilization (HRU) is high.

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Sexually transmitted infections – 30 years later

G.-S. Tiplica

doi : 10.1111/jdv.17667

Volume 35, Issue 11 p. 2285-2286

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High prevalence of syphilis in women, minors and precarious patients: a cross-sectional study in a Reunion Island sexually transmitted infection clinic, 2017–2020

A. Delfosse,N. Bouscaren,N. Dupin,J. Jaubert,P.L. Tran,C. Saint Pastou,R. Manaquin,P. Poubeau,P. Gerardin,A. Bertolotti

doi : 10.1111/jdv.17572

Volume 35, Issue 11 p. 2287-2292

Syphilis is a sexually transmitted infection (STI) with a global prevalence estimated at 0.5% in 2012. Syphilis has been on the rise among men who have sex with men (MSM) in high-income countries and remains at endemic levels in low- and middle-income countries. This trend, however, has not been observed in Reunion Island.

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High rate of self-improving phenotypes in children with non-syndromic congenital ichthyosis: case series from south-western Germany

L. Frommherz,A. Krause,J. Kopp,A. Hotz,S. Hübner,A. Reimer-Taschenbrecker,F. Casetti,B. Zirn,J. Fischer,C. Has

doi : 10.1111/jdv.17524

Volume 35, Issue 11 p. 2293-2299

Non-syndromic congenital ichthyosis describes a heterogeneous group of hereditary skin disorders associated with erythroderma and scaling at birth. Although both severe and mild courses are known, the prediction of the natural history in clinical practice may be challenging.

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An innovative application of follicular unit extraction technique in the treatment of bromhidrosis

H. Li,X. Zhang,W. Wei,L. Zhang,Z. Chen,M. Cao,J. Cheng,L. Du,J. Zhao,Z. Fang,X. Li,P. Chen

doi : 10.1111/jdv.17571

Volume 35, Issue 11 p. 2300-2304

Surgery is the most effective way to treat bromhidrosis, but postoperative complications are still the biggest obstacles for patients to choose surgical treatment.

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Vitiligo: 30 years to put together the puzzle pieces and to give rise to a new era of therapeutic options

T. Passeron

doi : 10.1111/jdv.17652

Volume 35, Issue 11 p. 2305-2307

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Raman spectroscopy reveals collagen and phospholipids as major components of hyalinosis in the arteriolosclerotic ulcer of Martorell

J. Deinsberger,M. Felhofer,J.P. Kläger,P. Petzelbauer,N. Gierlinger,B. Weber

doi : 10.1111/jdv.17573

Volume 35, Issue 11 p. 2308-2316

Arteriolosclerotic ulcers of Martorell are histologically characterized by hyaline arteriolosclerosis resulting in concentric occlusion of the arteriolar lumina. Although several authors have previously reported on hyaline changes in hypertensive arteriolopathies, so far, little information is available on the molecular composition of hyaline wall depositions.

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Fluorescence advanced videodermoscopy: a new method of hairs and scalp evaluation. Comparison with trichoscopy.

A. Rossi,F. Magri,G. Caro,S. Michelini,M. Di Fraia,M.C. Fortuna,G. Pellacani,M. Carlesimo

doi : 10.1111/jdv.17558

Volume 35, Issue 11 p. 2317-2323

Non-invasive diagnostic methods in clinical dermatology are widely used to reduce the need for invasive techniques, with great advantages in terms of cost and time. Dermoscopy is the reference test for the in vivo diagnosis of cutaneous lesions, and when it is performed on the scalp region it is named trichoscopy. Fluorescence advanced videodermoscopy (FAV) has been lately proposed as a new non-invasive method for the in vivo skin examination at high magnification, with cell-level resolution. So far, it has shown promising results for the assessment of melanocytic and vascular lesions and for the in vivo diagnosis of parasitosis.

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Development and validation of the Physician's Global Assessment of Fingernail Psoriasis

S. Hudgens,P. Rich,Z. Geng,D. Williams,A. Fleischer,A. Ganguli

doi : 10.1111/jdv.17387

Volume 35, Issue 11 p. 2324-2330

Several clinician-rated scoring systems are available to assess nail psoriasis severity, but only one has been partially validated.

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Announcement

doi : 10.1111/jdv.17715

Volume 35, Issue 11 p. 2331-2331

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Announcement

doi : 10.1111/jdv.17716

Volume 35, Issue 11 p. 2332-2332

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A review of nail findings associated with COVID-19 infection

E. Hadeler,B.W. Morrison,A. Tosti

doi : 10.1111/jdv.17448

Volume 35, Issue 11 p. e699-e709

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Low incidence rate of respiratory and viral infections over 5 years of treatment with tildrakizumab in patients with moderate-to-severe psoriasis: pooled analysis from reSURFACE 1 and reSURFACE 2 phase 3 trials

D. Thaçi,D. Jullien,A. Egeberg,J.M. Carrascosa,J.J. Wu,I. Pau-Charles,P. Gisondi

doi : 10.1111/jdv.17427

Volume 35, Issue 11 p. e709-e711

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Delayed cutaneous reaction to ChAdOx1 nCoV-19 vaccine: Is it an ‘AstraZeneca arm’?

J.E. Kim,H. Lee,S.S. Paik,J.-Y. Moon,H.J. Yoon,S.-H. Kim

doi : 10.1111/jdv.17476

Volume 35, Issue 11 p. e711-e714

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Impact of the COVID-19 pandemic on melanoma diagnosis

P. Gisondi,S. Cazzaniga,S. Di Leo,S. Piaserico,F. Bellinato,M. Pizzolato,A. Gatti,A. Eccher,M. Brunelli,D. Saraggi,G. Girolomoni,L. Naldi

doi : 10.1111/jdv.17493

Volume 35, Issue 11 p. e714-e715

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Generalized eczematous reactions to the Pfizer-BioNTech COVID-19 vaccine

A.C. Leasure,S.E. Cowper,J. McNiff,J.M. Cohen

doi : 10.1111/jdv.17494

Volume 35, Issue 11 p. e716-e717

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Erythema multiforme after CoronaVac vaccination

N.T. Lopes,C.E.O. Pinilla,A.C. Gerbase

doi : 10.1111/jdv.17495

Volume 35, Issue 11 p. e717-e719

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Widespread purpura annularis telangiectodes following mRNA SARS-CoV-2 vaccine

D. Falkenhain-López,C. Gutiérrez-Collar,J. Arroyo-Andrés,I. Gallego-Gutiérrez,J.L. Rodríguez-Peralto,A. Sánchez-Velázquez

doi : 10.1111/jdv.17497

Volume 35, Issue 11 p. e719-e721

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Pityriasis rosea developing after COVID-19 vaccination

O.Y. Marcantonio-Santa Cruz,A. Vidal-Navarro,D. Pesqué,A.M. Giménez-Arnau,R.M. Pujol,G. Martin-Ezquerra

doi : 10.1111/jdv.17498

Volume 35, Issue 11 p. e721-e722

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Development of eruptive pseudoangiomatosis following COVID-19 immunization – Apropos of 5 cases

A. Mohta,S. K. Jain,R. D. Mehta,A. Arora

doi : 10.1111/jdv.17499

Volume 35, Issue 11 p. e722-e725

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Pernio-like skin lesions after the second dose of Pfizer-BioNTech COVID-19 vaccine

N. Cameli,M. Silvestri,M. Mariano,S.P. Nisticò,A. Cristaudo

doi : 10.1111/jdv.17500

Volume 35, Issue 11 p. e725-e727

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New onset of remitting seronegative symmetrical synovitis with pitting oedema and palmoplantar psoriasis flare-up after Sars-Cov-2 vaccination

L. Quattrini,L. Verardi,G. Caldarola,G. Peluso,C. De Simone,M. D’Agostino

doi : 10.1111/jdv.17502

Volume 35, Issue 11 p. e727-e729

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New-onset cutaneous lichen planus triggered by COVID-19 vaccination

R. Merhy,A.-S. Sarkis,J. Kaikati,L. El Khoury,S. Ghosn,F. Stephan

doi : 10.1111/jdv.17504

Volume 35, Issue 11 p. e729-e730

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‘COVID arm’ – histological features of a delayed-type hypersensitivity reaction to Moderna mRNA-1273 SARS-CoV2 vaccine

W. Kempf,N. Kettelhack,F. Kind,S. Courvoisier,J. Galambos,K. Pfaltz

doi : 10.1111/jdv.17506

Volume 35, Issue 11 p. e730-e732

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Transition of cutaneous into systemic lupus erythematosus following adenoviral vector-based SARS-CoV-2 vaccination

A. Kreuter,S.-N. Burmann,B. Burkert,F. Oellig,A.-L. Michalowitz

doi : 10.1111/jdv.17514

Volume 35, Issue 11 p. e733-e735

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Reduction in the number of early melanomas diagnosed during the COVID-19 pandemic: a single-centre cohort study

E. Koch,F. Villanueva,M.A. Marchetti,Á. Abarzúa-Araya,C. Cárdenas,J.C. Castro,F. Dominguez,K. Droppelmann,N. Droppelmann,H. Galindo,A. León,J. Madrid,M. Molgó,S. Mondaca,P.H. Montero,P. Uribe,M.A. Villaseca,E. Vinés,C. Navarrete-Dechent

doi : 10.1111/jdv.17522

Volume 35, Issue 11 p. e735-e737

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A skin reaction with rust-like discolouration to mRNA COVID-19 vaccine

R. Pasternack,S. Pohjavaara

doi : 10.1111/jdv.17543

Volume 35, Issue 11 p. e737-e738

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Dermatoses caused by face mask wearing during the COVID-19 pandemic

O.Yu. Olisova,N.P. Teplyuk,E.V. Grekova,A.A. Lepekhova

doi : 10.1111/jdv.17546

Volume 35, Issue 11 p. e738-e741

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Small-vessel vasculitis following Oxford-AstraZeneca vaccination against SARS-CoV-2

L. Guzmán-Pérez,M. Puerta-Peña,D. Falkenhain-López,J. Montero-Menárguez,C. Gutiérrez-Collar,J.L. Rodríguez-Peralto,J. Sanz-Bueno

doi : 10.1111/jdv.17547

Volume 35, Issue 11 p. e741-e743

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Omalizumab prevents anaphylactoid reactions to mRNA COVID-19 vaccine

A. Smola,S. Samadzadeh,L. Müller,O. Adams,B. Homey,P. Albrecht,S. Meller

doi : 10.1111/jdv.17549

Volume 35, Issue 11 p. e743-e745

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Small vessel vasculitis related to varicella-zoster virus after Pfizer-BioNTech COVID-19 vaccine

F. Nastro,G. Fabbrocini,F. di Vico,C. Marasca

doi : 10.1111/jdv.17550

Volume 35, Issue 11 p. e745-e747

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New-onset acral lesions on hands after administration of mRNA-1273 vaccine against SARS-CoV-2: clinical images and histopathological study of three cases

D. Revilla-Nebreda,M. Roncero-Riesco,Á. Santos-Briz,M. Medina-Migueláñez,N. Segurado-Tostón,C. Román-Curto

doi : 10.1111/jdv.17553

Volume 35, Issue 11 p. e747-e749

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Herpes Zoster following SARS-CoV-2 vaccination – a series of four cases

M. Alpalhão,P. Filipe

doi : 10.1111/jdv.17555

Volume 35, Issue 11 p. e750-e752

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New onset of mainly guttate psoriasis after COVID-19 vaccination: a case report

M. Lehmann,P. Schorno,R.E. Hunger,K. Heidemeyer,L. Feldmeyer,N. Yawalkar

doi : 10.1111/jdv.17561

Volume 35, Issue 11 p. e752-e755

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Health-related quality of life in paediatric patients with vitiligo: a systematic review and meta-analysis

J. Nathalie,J. Chang,K. Ezzedine,M. Rodrigues

doi : 10.1111/jdv.17382

Volume 35, Issue 11 p. e755-e756

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Mucocutaneous leishmaniasis complicating systemic lupus erythematosus and responding to high dose amphotericin B

A.L. Matos,C. Figueiredo,F. Alves,N. Pereira,M. Gonçalo

doi : 10.1111/jdv.17423

Volume 35, Issue 11 p. e756-e758

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Lupus erythematosus tumidus in a patient with mycosis fungoides stage IB after complete response to PUVA

P.A. Vieyra-Garcia,L. Cerroni,R.A. Clark,P. Wolf

doi : 10.1111/jdv.17425

Volume 35, Issue 11 p. e758-e760

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A blinking knee: Quincke’s sign as a reaction to insect bite in a chronic lymphocytic leukaemia patient

E. Robustelli Test,E. Moggio,P. Sena,D.M. Gambini

doi : 10.1111/jdv.17426

Volume 35, Issue 11 p. e761-e762

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The spectrum of morphologic patterns of nodular melanoma: a study of the International Dermoscopy Society

A. Niforou,D. Sgouros,A. Lallas,A. Zaras,A. Scope,H. Tsao,G. Argenziano,C. Longo,H. Kittler,A. Stratigos,IDS Thin NM Project Investigators

doi : 10.1111/jdv.17428

Volume 35, Issue 11 p. e762-e765

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Use of self-applied sculptured gel nails may increase the risk of allergy to (meth)acrylates in children and adolescents

M. Tramontana,K. Hansel,L. Bianchi,R. Marietti,L. Stingeni

doi : 10.1111/jdv.17429

Volume 35, Issue 11 p. e765-e767

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HAc40 is a novel microbiome modulator, effective on atopic dermatitis in children: data from two pilot vehicle-controlled trials

R. Sacchetti,G. Gregori,E. Moggio,L. Gobbo,L. Bonzano,G. Pellacani

doi : 10.1111/jdv.17431

Volume 35, Issue 11 p. e767-e768

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A study of corticophobia in adult psoriasis patients: a French cross-sectional observational study

E. Moreau,H. Rousseau,A. Marzouki Zerouali,E. Melgar,J. Henry,J.L. Schmutz,G.F. Escobar,A.C. Bursztejn

doi : 10.1111/jdv.17435

Volume 35, Issue 11 p. e768-e770

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Aicardi–Goutières syndrome: a possible explanation of angiokeratoma of Mibelli

E. Cinotti,M. Bertello,C. Habougit,F. Rongioletti,F. Cambazard,J.C. Antoine,L. Tognetti,P. Rubegni,J.L. Perrot

doi : 10.1111/jdv.17440

Volume 35, Issue 11 p. e770-e772

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Mobile health skin cancer risk assessment campaign using artificial intelligence on a population-wide scale: a retrospective cohort analysis

T.E. Sangers,T. Nijsten,M. Wakkee

doi : 10.1111/jdv.17442

Volume 35, Issue 11 p. e772-e774

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Two cases of quinine-induced fixed ‘drug’ eruption induced by long drinks

A.S. Bohne,C. Dietrich,K. Morrison,T. Schwarz,U. Wehkamp,M. Kaeding

doi : 10.1111/jdv.17453

Volume 35, Issue 11 p. e774-e776

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Diagnostic and management challenges of erosive pustular dermatosis of the scalp: a retrospective study in Greek population

S. Siskou,A. Lallas,K. Theodoropoulos,D. Sgouros,M. Trakatelli,A. Patsatsi,A. Trigoni,M. Manoli,C. Papageorgiou,K. Liopyris,A. Katoulis,A. Stratigos,D. Ioannides,E. Lazaridou,Z. Apalla

doi : 10.1111/jdv.17455

Volume 35, Issue 11 p. e776-e779

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Work-related hazards due to oak processionary moths: a pilot survey on medical symptoms

S. Forkel,J. Mörlein,M. Sulk,C. Beutner,W. Rohe,M.P. Schön,J. Geier,T. Buhl

doi : 10.1111/jdv.17456

Volume 35, Issue 11 p. e779-e782

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New compound heterozygous SPINK5 mutations in a Chinese infant with Netherton syndrome

Q. Wang,F. Qiu,H. Wu,Y.-M. Fan

doi : 10.1111/jdv.17457

Volume 35, Issue 11 p. e782-e784

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Facial seborrheic keratosis with unusual dermoscopic patterns can be differentiated from other skin malignancies by in vivo reflectance confocal microscopy

F. Farnetani,G. Pedroni,N. Lippolis,M. Giovani,S. Ciardo,J. Chester,S. Kaleci,C. Pezzini,C. Cantisani,A. Dattola,M. Manfredini,E. Dika,A. Patrizi,G. Pellacani

doi : 10.1111/jdv.17470

Volume 35, Issue 11 p. e784-e787

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Prevalence of adult atopic dermatitis in the general population, with a focus on moderate-to-severe disease: results from the Lifelines Cohort Study

J. Zhang,L. Loman,A.N. Voorberg,M.L.A. Schuttelaar

doi : 10.1111/jdv.17471

Volume 35, Issue 11 p. e787-e790

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Hair flag sign: Macroscopic and trichoscopic feature of hair regrowth in alopecia areata

L.T. Fernández,D.E. Kubelis-López,F.Z. Muñoz-Garza,J. Ocampo-Candiani,E.L. Alba-Rojas

doi : 10.1111/jdv.17473

Volume 35, Issue 11 p. e790-e792

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Erythema punctatum Higuchi: reconsidering its relationship with adrenergic urticaria and eruptive pseudoangiomatosis

A. Mori,Y. Kaku,T. Dainichi

doi : 10.1111/jdv.17474

Volume 35, Issue 11 p. e792-e793

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Psoriasis vs. its mimickers: when the dermatoscope casts light on challenging cases in everyday clinical practice

I. Papadimitriou,K. Bakirtzi,A. Lallas,E. Vakirlis,E. Sotiriou,E. Lazaridou,D. Ioannides

doi : 10.1111/jdv.17475

Volume 35, Issue 11 p. e793-e796

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Successful treatment with narrowband ultraviolet B phototherapy in prurigo pigmentosa

M.S. Jang,K.S. Suh,D.I. Kwon,J.H. Jung,S.H. Seong,K.H. Lee,J.H. Kang,J.B. Park

doi : 10.1111/jdv.17477

Volume 35, Issue 11 p. e796-e798

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Meek micrografting: a novel surgical technique for the treatment of depigmentation

V.S. Narayan,N.F. Post,P.P.M. Van Zuijlen,M.W. Bekkenk,A. Wolkerstorfer

doi : 10.1111/jdv.17478

Volume 35, Issue 11 p. e798-e801

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Atrichia with papular lesions: a differential diagnosis of alopecia universalis not to be missed

A. Ibrahim,F. Buket Basmanav,G. Bohelay,A. Lévy,R.C. Betz,F. Caux

doi : 10.1111/jdv.17479

Volume 35, Issue 11 p. e801-e803

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Two cases of unique presentation of anaphylaxis to Japanese butterbur scapes and literature review

M. Onaka,H. Mitsui,A. Honobe-Tabuchi,N. Deguchi,Y. Ogawa,S. Shimada,T. Kawamura

doi : 10.1111/jdv.17481

Volume 35, Issue 11 p. e803-e804

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Genetic polymorphisms in immunity related genes and the vitamin D receptor gene and risk of cutaneous T-cell lymphoma in Greek population

A. Velissari,E. Lakiotaki,V. Nikolaou,K.V. Argyropoulos,A. Stratigos,G. Daikos,K. Konstantopoulos,M. Siakantaris

doi : 10.1111/jdv.17482

Volume 35, Issue 11 p. e805-e807

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Human papillomavirus type 67 in cutaneous squamous cell dysplasia and carcinoma

A. Kreuter,S. Silling,A. Potthoff,F. Oellig,A.L. Michalowitz,U. Wieland

doi : 10.1111/jdv.17496

Volume 35, Issue 11 p. e807-e809

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The art of observation: visual literacy for dermatologists

R. Matthews,A. Wray,S. Walsh,C.E.M. Griffiths,H.S. Young

doi : 10.1111/jdv.17501

Volume 35, Issue 11 p. e809-e811

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Temperature-controlled laminar airflow in adult atopic dermatitis patients – an observational study

S. Traidl,L.M. Roesner,P. Kienlin,G. Begemann,A. Schreiber,T. Werfel,A. Heratizadeh

doi : 10.1111/jdv.17507

Volume 35, Issue 11 p. e812-e815

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National trends in psoriasis readmissions: a longitudinal study of the nationwide readmission database from 2010 to 2018

E. Edigin,M.M. Rivera Pavon,P.O. Eseaton,C. Hernandez,A. Manadan

doi : 10.1111/jdv.17508

Volume 35, Issue 11 p. e815-e817

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Lichen sclerosus et atrophicus on dimples: a striking example of immunocompromised cutaneous district

O. Ozbagcivan,D.F. Ayozcan,B. Lebe

doi : 10.1111/jdv.17509

Volume 35, Issue 11 p. e817-e819

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The right default mode network is associated with the severity of chronic itch

H. Mochizuki,C.D. Kursewicz,J.S. Nomi,G. Yosipovitch

doi : 10.1111/jdv.17510

Volume 35, Issue 11 p. e819-e821

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A case of delayed antihistamine cutaneous drug eruption and piperidine derivative cross-reaction

M. Lagassy,M. Aroux-Pavard,P. Joly,F. Tetart,O. Bauvin

doi : 10.1111/jdv.17511

Volume 35, Issue 11 p. e821-e823

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A rare case of neuro- and otosyphilis in secondary syphilis

S. Traidl,Y. Angela,A. Stender,A. Kulberg,M. Tronnier,N.K. Prenzler,M.P. Wattjes,A. Kapp,M. Stangel,V. Schacht,T. Werfel

doi : 10.1111/jdv.17512

Volume 35, Issue 11 p. e823-e826

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Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders

R.R.Z. Conic,J. Maghfour,G. Damiani,W. Bergfeld

doi : 10.1111/jdv.17513

Volume 35, Issue 11 p. e826-e828

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An integrated safety analysis of treatment-emergent fungal infections in patients with psoriasis treated with ixekizumab from 16 clinical studies

A. Blauvelt,M. Ramharter,A.D. Cohen,W. Xu,H. Patel,C. Schuster,E. Riedl,L. Puig

doi : 10.1111/jdv.17554

Volume 35, Issue 11 p. e828-e831

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