Journal of the European Academy of Dermatology and Venereology




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Issue Information

doi : 10.1111/jdv.16658

Volume 35, Issue 10 p. 1909-1914

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Editor’s Picks

doi : 10.1111/jdv.17616

Volume 35, Issue 10 p. 1915-1915

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Dermatology and JEADV on the rise – gaining more scientific awareness

J. Ring

doi : 10.1111/jdv.17605

Volume 35, Issue 10 p. 1916-1916

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Unsatisfactory agreement using current classification of maculopapular cutaneous mastocytosis

K. Brockow

doi : 10.1111/jdv.17563

Volume 35, Issue 10 p. 1917-1918

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An integrated approach is recommended in bullous pemphigoid

F. Poot

doi : 10.1111/jdv.17600

Volume 35, Issue 10 p. 1919-1920

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Clues to crack an uncommon clinical conundrum: distinguishing TEN from EMM

S. Walsh

doi : 10.1111/jdv.17535

Volume 35, Issue 10 p. 1921-1921

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Pioneers in Dermatology and Venereology: an interview with Professor Francisco Miguel Camacho Martinez

F.M. Camacho Martinez

doi : 10.1111/jdv.17602

Volume 35, Issue 10 p. 1922-1925

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European Guidelines (S3) on diagnosis and management of mucous membrane pemphigoid, initiated by the European Academy of Dermatology and Venereology – Part II

E. Schmidt,H. Rashid,A.V. Marzano,A. Lamberts,G. Di Zenzo,G.F.H. Diercks,S. Alberti-Violetti,R.J. Barry,L. Borradori,M. Caproni,B. Carey,M. Carrozzo,G. Cianchini,A. Corrà,F.G. Dikkers,C. Feliciani,G. Geerling,G. Genovese,M. Hertl,P. Joly,J.M. Meijer,V. Mercadante,D.F. Murrell,M. Ormond,H.H. Pas,A. Patsatsi,S. Rauz,B.D. van Rhijn,M. Roth,J. Setterfield,D. Zillikens,C.Prost,G. Zambruno,B. Horváth,F. Caux

doi : 10.1111/jdv.17395

Volume 35, Issue 10 p. 1926-1948

This guideline has been initiated by the task force Autoimmune Blistering Diseases of the European Academy of Dermatology and Venereology, including physicians from all relevant disciplines and patient organizations. It is a S3 consensus-based guideline that systematically reviewed the literature on mucous membrane pemphigoid (MMP) in the MEDLINE and EMBASE databases until June 2019, with no limitations on language. While the first part of this guideline addressed methodology, as well as epidemiology, terminology, aetiology, clinical presentation and outcome measures in MMP, the second part presents the diagnostics and management of MMP. MMP should be suspected in cases with predominant mucosal lesions. Direct immunofluorescence microscopy to detect tissue-bound IgG, IgA and/or complement C3, combined with serological testing for circulating autoantibodies are recommended. In most patients, serum autoantibodies are present only in low levels and in variable proportions, depending on the clinical sites involved. Circulating autoantibodies are determined by indirect IF assays using tissue substrates, or ELISA using different recombinant forms of the target antigens or immunoblotting using different substrates. The major target antigen in MMP is type XVII collagen (BP180), although in 10–25% of patients laminin 332 is recognized. In 25–30% of MMP patients with anti-laminin 332 reactivity, malignancies have been associated. As first-line treatment of mild/moderate MMP, dapsone, methotrexate or tetracyclines and/or topical corticosteroids are recommended. For severe MMP, dapsone and oral or intravenous cyclophosphamide and/or oral corticosteroids are recommended as first-line regimens. Additional recommendations are given, tailored to treatment of single-site MMP such as oral, ocular, laryngeal, oesophageal and genital MMP, as well as the diagnosis of ocular MMP. Treatment recommendations are limited by the complete lack of high-quality randomized controlled trials.

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Position statement on classification of basal cell carcinomas. Part 1: unsupervised clustering of experts as a way to build an operational classification of advanced basal cell carcinoma based on pattern recognition

J.J. Grob,A. Guminski,J. Malvehy,N. Basset-seguin,B. Bertrand,P. Fernandez-Penas,R. Kaufmann,I. Zalaudek,C. Gaudy-Marqueste,M.C. Fargnoli,L. Tagliaferri,B. Fertil,V. Del Marmol,A. Stratigos,C. Garbe,K. Peris

doi : 10.1111/jdv.17466

Volume 35, Issue 10 p. 1949-1956

No simple classification system has emerged for ‘advanced basal cell carcinomas’, and more generally for all difficult-to-treat BCCs (DTT-BCCs), due to the heterogeneity of situations, TNM inappropriateness to BCCs, and different approaches of different specialists.

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Patch test informed consent form: position statement by European Academy of Dermatology and Venereology Task Force on Contact Dermatitis

A. Balato,E. Scala,F. Ayala,A. Bauer,M.-N. Crépy,M. Gonçalo,J. Duus Johansen,S.M. John,T. Rustemeyer,N. Wagner,M. Wilkinson,A. Giménez-Arnau

doi : 10.1111/jdv.17483

Volume 35, Issue 10 p. 1957-1962

To our knowledge, an international consensus is lacking regarding the development of an adequate informed consent form for a patch test (PT) and the information that should be included in such document.

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Adult skin acute stress responses to short-term environmental and internal aggression from exposome factors

T. Passeron,C.C. Zouboulis,J. Tan,M.L. Andersen,R. Katta,X. Lyu,L. Aguilar,D. Kerob,A. Morita,J. Krutmann,E.M.J. Peters

doi : 10.1111/jdv.17432

Volume 35, Issue 10 p. 1963-1975

Exposome factors that lead to stressed skin can be defined as any disturbance to homeostasis from environmental (meteorological factors, solar radiation, pollution or tobacco smoke) and/or internal exposure (unhealthy diet, hormonal variations, lack of sleep, psychosocial stress). The clinical and biological impact of chronic exposome effects on skin functions has been extensively reviewed, whereas there is a paucity of information on the impact of short-term acute exposure. Acute stress, which would typically last minutes to hours (and generally no more than a week), provokes a transient but robust neuroendocrine-immune and tissue remodelling response in the skin and can alter the skin barrier. Firstly, we provide an overview of the biological effects of various acute stressors on six key skin functions, namely the skin physical barrier, pigmentation, defences (antioxidant, immune cell-mediated, microbial and microbiome maintenance), structure (extracellular matrix and appendages), neuroendocrine and thermoregulation functions. Secondly, we describe the biological and clinical effects on adult skin from individual exposome factors that elicit an acute stress response and their consequences in skin health maintenance. Clinical manifestations of acutely stressed skin may include dry skin that might accentuate fine lines, oily skin, sensitive skin, pruritus, erythema, pale skin, sweating, oedema and flares of inflammatory skin conditions such as acne, rosacea, atopic dermatitis, pigmentation disorders and skin superinfection such as viral reactivation. Acute stresses can also induce scalp sensitivity, telogen effluvium and worsen alopecia.

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A Bayesian network meta-analysis of comparison of cancer therapeutic vaccines for melanoma

P. Lau,M. Shen,F. Ma,Y. Chen,J. Zhang,J. Su,X. Chen,H. Liu

doi : 10.1111/jdv.17437

Volume 35, Issue 10 p. 1976-1986

Several approaches to active immunotherapy for melanoma, including peptide-based vaccines (PVs), autologous tumour cell vaccines (TCVs), allogeneic TCVs and autologous dendritic cell vaccines (DCVs), have been investigated in clinical trials. However, comprehensive evidence comparing these interventions remains unavailable. The objective of this study was to expand previous work to compare and rank the immunotherapeutic strategies for melanoma in terms of overall survival and toxic effects with a Bayesian network meta-analysis. Methodologically, we performed a network meta-analysis of head-to-head randomized controlled trials comparing and ranking cancer vaccine approaches for patients with melanoma. PubMed, MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, the WHO International Clinical Trials Registry Platform and ClinicalTrials.gov were searched up to 31 July 2020. We estimated summary hazard ratios for death and risk ratios for toxicity. The effects of the underlying prognostic variable on survival benefits were examined by meta-regression. We performed subgroup analysis for the outcomes based on metastatic categories. Overall, we identified 4776 citations, of which 15 head-to-head randomized controlled trials (3162 participants) were included in the analysis. In terms of efficacy, allogeneic tumour cell vaccines plus immunotherapy adjuvants, peptide-based vaccines plus immunotherapy adjuvants and standard therapy were more effective than peptide vaccines. The proportion of women was inversely associated with mortality risk. For safety, all treatments were inferior to allogeneic tumour cell vaccines except for allogeneic tumour cell vaccines plus chemotherapy. Peptide vaccines plus immunotherapy adjuvants led to an increased risk of adverse events compared to allogeneic tumour cell vaccines plus immunotherapy adjuvants. These results suggest that allogeneic TCV and autologous DCV are better than standard therapy. PV plus immune modulators are the most effective strategy among all comparable strategies but is associated with increased toxicity. Any combination regimens for cancer therapeutic vaccines need to be balanced between risk and benefit profiles.

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Measurement properties of patient-reported outcome measures for eczema control: a systematic review

B.L. Stuart,L. Howells,R.L. Pattinson,J.R. Chalmers,D. Grindlay,N.K. Rogers,E. Grinich,T. Pawlitschek,E.L. Simpson,K.S. Thomas

doi : 10.1111/jdv.17335

Volume 35, Issue 10 p. 1987-1993

Atopic eczema (herein referred to as ‘eczema’) is a skin disease characterized by remitting and relapsing symptoms. The Harmonising Outcome Measures for Eczema (HOME) initiative was developed to establish a core outcome set (COS) for eczema to be measured for all future eczema trials. The core outcome set for atopic eczema clinical trials includes the domain for patient-reported eczema control, but a review of the validation of available eczema control instruments was lacking. We aimed to review the literature and systematically assess the measurement properties of validated patient-reported outcome instruments that capture eczema control. PubMed and Ovid EMBASE were searched up to 24 January 2020 for any study that reported on PROM instrument development or validation. The COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) criteria were used to assess the quality of eligible studies. We screened 12 036 titles and abstracts and 58 full texts. A total of 12 papers were included, reporting on seven PROMS. These were assessed with respect to development, reliability, construct validity and responsiveness. Two instruments, Recap of Atopic Eczema (RECAP) and the Atopic Dermatitis Control Tool (ADCT), have been developed and validated to a sufficient standard to support their recommendation as patient-reported outcome instruments for measuring control of atopic eczema as part of the HOME Core Outcome Set.

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Skin adverse events related to personal protective equipment: a systematic review and meta-analysis

T. Montero-Vilchez,C. Cuenca-Barrales,A. Martinez-Lopez,A. Molina-Leyva,S. Arias-Santiago

doi : 10.1111/jdv.17436

Volume 35, Issue 10 p. 1994-2006

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global pandemic that has spread all over the word. To avoid the virus transmission, healthcare workers must wear adequate personal protective equipment (PPE). PPE is associated with several side events, including skin reactions. The objective of this study was to summarize the prevalence, type and risk factors for cutaneous adverse events related to PPE and prevention measures to avoid them. A systematic review and meta-analysis was conducted using MEDLINE, Scopus and EMBASE databases from conception to 21 January 2021. All types of epidemiological studies regarding skin adverse events related to PPE were included. The literature search identified 1007 references, 35 of them met the eligible criteria and were included for analysis, representing 31 453 participants. The media of skin side events related to PPE was 75.13%. The rate of cutaneous adverse events related to mask was 57.71%, and those associated with gloves and hand hygiene products was 49.16%. Most common skin adverse events were contact dermatitis, acne and itching. The most damaged anatomical regions were the nasal bridge, the cheeks and the hands. The duration of PPE wearing was the most common risk factor. Frequent handwashing, gloves and masks were the agents most frequently related to skin reactions. N95 respirators were the most harmful mask type for the skin. Hydrocolloid use prevented from developing skin adverse events related to masks. In conclusion, the rate of cutaneous adverse events related to PPE use is high. A longer duration of PPE wearing was the most common risk factor. Using hydrocolloid could prevent from skin injuries related to mask use.

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Trichomonas vaginalis and growing concern over drug resistance: a systematic review

M. Marques-Silva,C. Lisboa,N. Gomes,A.G. Rodrigues

doi : 10.1111/jdv.17461

Volume 35, Issue 10 p. 2007-2021

In the late 90s, a sharp increase of treatment failures of Trichomonas vaginalis (TV) infections with metronidazole (MTZ) was reported, representing a problem due to limited treatment options. We proposed to review the available evidence on the frequency of MTZ resistance by TV isolates and the relationship between treatment failure and in vitro resistance to MTZ. A systematic review based on the PRISMA guidelines was conducted by searching published studies in three different databases (PubMed, Scopus and Web of Science) up to December 2020. The extracted studies were uploaded to Covidence software; screening was guided based on inclusion and exclusion criteria. Additionally, different articles were included through other sources. For each article, study design, objectives, study population and key outcomes were summarized. We found 403 references from the databases and four extra studies. After duplicate removal and screening of title, abstract and full text, 27 studies were included. The selected studies were published between 1983 and 2019; all except one addressed only vaginal TV infection. We identified four major populations in vitro MTZ resistance: two studies evaluated female adolescents; other two assessed HIV-positive women. Fifteen studies considered MTZ resistance in newly diagnosed vaginal TV infection. Finally, eight articles studied in vitro susceptibility of isolates from women with clinical resistant trichomoniasis. High level of in vitro MTZ resistance was rare; low-moderate level was described in most of the cases. Although clinical resistance to MTZ of trichomoniasis was widely reported, there was a paucity of prospective controlled studies. Our review unveiled the need to standardize susceptibility testing, to define breakpoints for detection of MTZ-resistant isolates and to correlate with clinical outcome. It is important to establish criteria to define clinical resistance to MTZ. Such a consensus would foster the development of surveillance studies about clinical and microbiological response to MTZ treatment.

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Perilesional sun damage as a diagnostic clue for pigmented actinic keratosis and Bowen’s disease

P. Weber,C. Sinz,C. Rinner,H. Kittler,P. Tschandl

doi : 10.1111/jdv.17464

Volume 35, Issue 10 p. 2022-2026

Chronic sun damage in the background is common in pigmented actinic keratoses and Bowen’s disease (pAK/BD). While explainable artificial intelligence (AI) demonstrated increased background attention for pAK/BD, humans frequently miss this clue in dermatoscopic images because they tend to focus on the lesion.

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ActiPso: definition of activity types for psoriatic disease: A novel marker for an advanced disease classification

U. Mrowietz,T. Dieckmann,S. Gerdes,S. Szymczak,R. von Spreckelsen,A. Körber

doi : 10.1111/jdv.17434

Volume 35, Issue 10 p. 2027-2033

Assessment of psoriasis is exclusively done measuring severity using somatic scores such as the psoriasis area and severity index or patient-reported outcomes such as the dermatology life quality index. There is no established tool to measure a patient's individual psoriasis activity over time.

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Complete clearance and Psoriasis Area and Severity Index response for brodalumab and ustekinumab by previous treatment history in AMAGINE-2 and AMAGINE-3

K. Reich,J.B. Hansen,L. Puig,M.P. Konstantinou,R.B. Warren

doi : 10.1111/jdv.17433

Volume 35, Issue 10 p. 2034-2044

The pathway for treatment of psoriasis is partly dependent upon disease severity, and patients may experience inadequate response at any point along the treatment pathway. Patients who repeatedly fail therapy represent a population in whom effective and well-tolerated treatment options are limited.

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A multicentre open-label study of apremilast in palmoplantar pustulosis (APLANTUS)

D. Wilsmann-Theis,C. Kromer,S. Gerdes,C. Linker,N. Magnolo,R. Sabat,K. Reich,R. Mössner

doi : 10.1111/jdv.17441

Volume 35, Issue 10 p. 2045-2050

Palmoplantar pustulosis (PPP) is a chronic skin disease with painful erythematous scaly or crusty lesions and pustules on the palms and soles. Apremilast is a phosphodiesterase 4 inhibitor that has proven effective in the therapy of psoriasis, psoriatic arthritis and in oral ulcers associated with Behcet’s disease.

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Childhood epidermal necrolysis and erythema multiforme major: a multicentre French cohort study of 62 patients

L. Giraud-Kerleroux,N. Bellon,A. Welfringer-Morin,S. Leclerc-Mercier,I. Costedoat,J. Coquin,A. Brun,A.-M. Roguedas-Contios,C. Bernier,B. Milpied,F. Tétart,A. Du Thanh,N. Cordel,B. Bensaid,C. Fargeas,M. Tauber,S. Renolleau,F. Boralevi,S. Ingen-Housz-Oro,C. Bodemer

doi : 10.1111/jdv.17469

Volume 35, Issue 10 p. 2051-2058

The distinction between epidermal necrolysis [EN; including Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and overlap syndrome] and erythema multiforme major (EMM) in children is confusing. We aimed to better describe and compare these entities.

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Longitudinal association between polypharmacy and development of pruritus: a Nationwide Cohort Study in a Japanese Population

T. Kogame,T. Kamitani,H. Yamazaki,Y. Ogawa,S. Fukuhara,K. Kabashima,Y. Yamamoto

doi : 10.1111/jdv.17443

Volume 35, Issue 10 p. 2059-2066

Although polypharmacy is known to cause side-effects due to drug–drug interactions, dermatological symptoms triggered by polypharmacy are not fully addressed.

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Coexistence of bullous pemphigoid with neuropsychiatric comorbidities is associated with anti-BP230 seropositivity

S. Ständer,C.M. Hammers,A. Vorobyev,E. Schmidt,J.E. Hundt,C.D. Sadik,T. Lange,D. Zillikens,R.J. Ludwig,K. Kridin

doi : 10.1111/jdv.17304

Volume 35, Issue 10 p. 2067-2073

While clustering of bullous pemphigoid (BP) with neuropsychiatric diseases is well-established, the clinical and immunological profile of BP patients with this comorbidity remains to be decisively determined.

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The burden of neurological comorbidities in six autoimmune bullous diseases: a population-based study

K. Kridin,F. Hübner,A. Recke,R. Linder,E. Schmidt

doi : 10.1111/jdv.17465

Volume 35, Issue 10 p. 2074-2078

Apart from bullous pemphigoid (BP), the association of other autoimmune bullous diseases (AIBDs) with neurological conditions is poorly understood.

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Interobserver variability in the classification of childhood maculopapular cutaneous mastocytosis

A. Torrelo,L. Vergara-de-la-Campa,J.M. Azaña,S. Greenberger,J.M. Lam,L.P. Lawley,M.-A. Morren,J.V. Schaffer,I. García-Doval,A. Matito,I. Alvarez-Twose

doi : 10.1111/jdv.17345

Volume 35, Issue 10 p. 2079-2084

Maculopapular cutaneous mastocytosis (MPCM) in children is classified in two variants: (i) monomorphic variant, presenting with the small macules or papules typically seen in adult patients; and (ii) polymorphic variant with larger lesions of variable size and shape, typically seen in children. The definition of polymorphic and monomorphic variants is mostly intuitive, and a validation of this classification has not been done.

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Cerebriform sebaceous nevus: a subtype of organoid nevus due to specific postzygotic FGFR2 mutations

M. Theiler,L. Weibel,S. Christen-Zaech,V. Carmignac,A. Sorlin,K. Neuhaus,M. Chevarin,C. Thauvin-Robinet,C. Philippe,L. Faivre,P. Vabres,P. Kuentz

doi : 10.1111/jdv.17319

Volume 35, Issue 10 p. 2085-2090

Postzygotic mutations in FGFR2 have been identified in mosaic forms of acne, keratinocytic epidermal nevi, nevoid acanthosis nigricans / rounded and velvety epidermal nevus and in two fetuses with papillomatous pedunculated sebaceous nevus (PPSN).

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Dermoscopy of porokeratosis: results from a multicentre study of the International Dermoscopy Society

O. Zaar,S. Polesie,C. Navarrete-Dechent,E. Errichetti,B.N. Akay,J. Jaimes,H. Cabo,E. Cohen Sabban,J. Paoli

doi : 10.1111/jdv.17439

Volume 35, Issue 10 p. 2091-2096

The diagnosis of porokeratosis can be challenging, and knowledge about its dermoscopic features is limited.

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Plantar involvement correlates with obesity, pain and impaired mobility in epidermolysis bullosa simplex: a retrospective cohort study

A. Reimer-Taschenbrecker,M. Hess,A. Hotz,J. Fischer,L. Bruckner-Tuderman,C. Has

doi : 10.1111/jdv.17336

Volume 35, Issue 10 p. 2097-2104

Epidermolysis bullosa simplex (EBS) is the most common type of EB, a group of rare genodermatoses. Affected individuals suffer from skin blistering and report a high disease burden. In some EBS subtypes, plantar keratoderma (PK) has been described.

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Announcement

doi : 10.1111/jdv.17625

Volume 35, Issue 10 p. 2105-2105

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Announcement

doi : 10.1111/jdv.17626

Volume 35, Issue 10 p. 2106-2106

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Announcement

doi : 10.1111/jdv.17627

Volume 35, Issue 10 p. 2107-2107

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Announcement

doi : 10.1111/jdv.17628

Volume 35, Issue 10 p. 2108-2108

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Contemporary occurrence of Chilblain-like lesions and Pityriasis rosea during the COVID-19 pandemic

V. Piccolo,A. Bassi,G. Argenziano,C. Mazzatenta,M. Cutrone,I. Neri,R. Grimalt,T. Russo

doi : 10.1111/jdv.17409

Volume 35, Issue 10 p. e619-e620

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Ipsilateral herpes zoster after the first dose of BNT162b2 mRNA COVID-19 vaccine

I. Tessas,N. Kluger

doi : 10.1111/jdv.17422

Volume 35, Issue 10 p. e620-e622

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Acute postinfectious pityriasis rubra pilaris as a cutaneous manifestation in COVID-19: a case report and its dermoscopic features

D. Kadylak,W. Bara?ska-Rybak

doi : 10.1111/jdv.17424

Volume 35, Issue 10 p. e622-e624

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Patients with primary cutaneous lymphoma are at risk for severe COVID-19. Data from the Spanish Primary Cutaneous Lymphoma Registry

A. Sánchez-Velázquez,A. Bauer-Alonso,T. Estrach,D. Vega-Díez,P. Garcia-Muret,L. Haya,Y. Peñate,E. Acebo,R. Fernández de Misa,M. Blanes,H.J. Suh-Oh,R. Izu,E. Silva-Díaz,J. Sarriugarte,C. Román-Curto,R. Botella-Estrada,A. Mateu-Puchades,L. Prieto-Torres,V. Morillas,M. Morillo,P. Sánchez-Caminero,L. Calzado,A. Pérez-Ferriols,A. Pérez,J.D. Domínguez,M. Navedo,C. Muniesa,A. Combalia,J. Arroyo-Andrés,M.A. Descalzo,I. García-Doval,P.L. Ortiz-Romero

doi : 10.1111/jdv.17430

Volume 35, Issue 10 p. e624-e626

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Immune thrombocytopenic purpura associated with COVID-19 Pfizer-BioNTech BNT16B2b2 mRNA vaccine

P. K. Krajewski,J. C. Szepietowski

doi : 10.1111/jdv.17444

Volume 35, Issue 10 p. e626-e627

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Adverse skin reactions due to use of face masks: a prospective survey during the COVID-19 pandemic in Korea

S.J. Park,H.S. Han,S.H. Shin,K.H. Yoo,K. Li,B.J. Kim,S.J. Seo,K.Y. Park

doi : 10.1111/jdv.17447

Volume 35, Issue 10 p. e628-e630

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Chilblain-like lesions after BNT162b2 mRNA COVID-19 vaccine: a case report suggesting that ‘COVID toes’ are due to the immune reaction to SARS-CoV-2

C. Lesort,J Kanitakis,L. Donzier,D. Jullien

doi : 10.1111/jdv.17451

Volume 35, Issue 10 p. e630-e632

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Psoriasis flare-up associated with second dose of Pfizer-BioNTech BNT16B2b2 COVID-19 mRNA vaccine

P.K. Krajewski,?. Matusiak,J.C. Szepietowski

doi : 10.1111/jdv.17449

Volume 35, Issue 10 p. e632-e634

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Systemic drug-related intertriginous and flexural exanthema like eruption after CoronaVac vaccine

O.M. Orenay,I. Balta,D. Yigit,M. Eksioglu

doi : 10.1111/jdv.17454

Volume 35, Issue 10 p. e634-e635

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Describing the burden of the COVID-19 pandemic in people with psoriasis: findings from a global cross-sectional study

S.K. Mahil,M. Yates,Z.Z.N. Yiu,S.M. Langan,T. Tsakok,N. Dand,K.J. Mason,H. McAteer,F. Meynell,B. Coker,A. Vincent,D. Urmston,A. Vesty,J. Kelly,C. Lancelot,L. Moorhead,H. Bachelez,F. Capon,C.R. Contreras,C. De La Cruz,P. Di Meglio,P. Gisondi,D. Jullien,J. Lambert,L. Naldi,S. Norton,L. Puig,P. Spuls,T. Torres,R.B. Warren,H. Waweru,J. Weinman,M.A. Brown,J.B. Galloway,C.M. Griffiths,J.N. Barker,C.H. Smith,the PsoProtect study group

doi : 10.1111/jdv.17450

Volume 35, Issue 10 p. e636-e640

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The significance of exanthems in COVID-19 patients hospitalized at a tertiary care centre

R. Rrapi,S. Chand,J.A. Lo,C.K. Gabel,S. Song,Z. Holcomb,C. Iriarte,K. Moore,C.R. Shi,H. Song,F.D. Xia,D. Yanes,R. Gandhi,V.A. Triant,D. Kroshinsky

doi : 10.1111/jdv.17459

Volume 35, Issue 10 p. e640-e642

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Evolution of notified sexually transmitted infections in Barcelona during the first wave of the COVID-19 pandemic

G. Martin-Ezquerra,P. Monreal,L. Mercuriali,E. Cañas-Ruano,R.M. Pujol,X. Duran,M. Masferrer Niubò,P. Domingo,J. Villar-Garcia,J. Lopez-Contreras,A. Gonzalez-Cordón,P. Garcia-Olalla,M.-J. Barberá,STI-HIV group of Barcelona

doi : 10.1111/jdv.17460

Volume 35, Issue 10 p. e642-e645

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The first dose of COVID-19 vaccine may trigger pemphigus and bullous pemphigoid flares: is the second dose therefore contraindicated?

G. Damiani,A. Pacifico,F. Pelloni,M. Iorizzo

doi : 10.1111/jdv.17472

Volume 35, Issue 10 p. e645-e647

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Ulcus vulvae acutum and SARS-CoV-2: an aetiological role?

M.C. Alberelli,A. Panariello,M. Olivi,A. Borghi,P. Zedde,M. Corazza

doi : 10.1111/jdv.17463

Volume 35, Issue 10 p. e647-e649

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Development of severe pemphigus vulgaris following SARS-CoV-2 vaccination with BNT162b2

F. Solimani,Y. Mansour,D. Didona,A. Dilling,K. Ghoreschi,K. Meier

doi : 10.1111/jdv.17480

Volume 35, Issue 10 p. e649-e651

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Atopic dermatitis, dupilumab and cancers: a case series

N. Siliquini,M.T. Giura,R. Viola,S. Ribero,M. Panzone,P. Dapavo,M.T. Fierro,M. Ortoncelli,P. Quaglino

doi : 10.1111/jdv.17264

Volume 35, Issue 10 p. e651-e652

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Assessment of urticaria using a self-reported diagnosis tool (SRUD): a multicentre validation study

S. Tawil,C. Irani,R. Kfoury,S. Abramian,P. Salameh,K. Weller,M. Maurer,K. Ezzedine

doi : 10.1111/jdv.17277

Volume 35, Issue 10 p. e652-e654

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Evaluating the contributions of dermatologists in the management of systemic sclerosis: a retrospective analysis

L.K. Rangel,P. Adotama,P. Shah,K. Lo Sicco,A.N. Femia

doi : 10.1111/jdv.17288

Volume 35, Issue 10 p. e654-e656

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Impact of an e-learning programme on pharmacists’ management of atopic dermatitis

A.-C. Garreau,J.-F. Stalder,S. Méry,P. Bunouf,C. Jean-Decoster,A. Nosbaum, on behalf of the Eczema Foundation, the French Group on Therapeutic Education in Dermatology (GET)

doi : 10.1111/jdv.17326

Volume 35, Issue 10 p. e656-e659

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Anaphylaxis to vaccination and polyethylene glycol: a perspective from the European Anaphylaxis Registry

M. Kraft,J.M. Renaudin,L.F. Ensina,A. Kleinheinz,M.B. Bilò,K. Scherer Hofmeier,S. Dölle-Bierke,M. Worm

doi : 10.1111/jdv.17327

Volume 35, Issue 10 p. e659-e662

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Stevens–Johnson syndrome induced by tonic water

S. Wada,T. Namiki,S. Tokoro,K. Miura,H. Yokozeki

doi : 10.1111/jdv.17368

Volume 35, Issue 10 p. e662-e663

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Toxic epidermal necrolysis-like graft vs host disease following orthotopic liver transplantation: a case with skin chimerism

A. López-Valle,A. García-Reyne,C. Loinaz-Segurola,J. Sanchez-Pina,J.L. Rodríguez-Peralto,C. Zarco-Olivo

doi : 10.1111/jdv.17371

Volume 35, Issue 10 p. e663-e665

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Subungual squamous cell carcinoma in a BAP1 germline pathogenic variant carrier

S. Idoudi,B. Bressac- de Paillerets,B. Balme,M.-N. Bonnet-Dupeyron,L. Golmard,L. Thomas

doi : 10.1111/jdv.17372

Volume 35, Issue 10 p. e665-e667

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Certain public-reported immune-mediated adverse events for PD-1 inhibitors in melanoma occur at higher rates than in clinical trials

N. Gupta,C. Cullison,A. Mally,L. Xiang,S.T. Hill,M.G. Beveridge

doi : 10.1111/jdv.17373

Volume 35, Issue 10 p. e667-e670

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Histopathological features and outcomes of DUSP22 rearrangement in primary cutaneous anaplastic large cell lymphoma: a case report and review of the literature

L.M. Nieto-Benito,V. Parra-Blanco,Y. Gómez-Navarro,J. Menárguez-Palanca,A. Pulido-Pérez

doi : 10.1111/jdv.17375

Volume 35, Issue 10 p. e670-e672

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Atrophic papulosis: the wedge-shaped skin necrosis overlays an active lesion

C.C. Zouboulis,L.S. Shapiro,C.M. Magro

doi : 10.1111/jdv.17377

Volume 35, Issue 10 p. e672-e674

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Folliculitis decalvans and lichen planopilaris phenotypic spectrum: case report of two paediatric cases

P.M. Ramos,D.F. Melo,L.R. Lemes,G. Alcantara,H.A. Miot,M.R. Lyra,T.J. de S. Vargas

doi : 10.1111/jdv.17379

Volume 35, Issue 10 p. e674-e676

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Demographic and clinical characteristics of patients with both psoriasis and vitiligo in a cohort of vitiligo patients: a cross-sectional study

D. Canu,J. Shourick,N. Andreu,A. Gey,F. Ballanger-Désolneux,H. Barailler,K. Boniface,K. Ezzedine,J. Seneschal

doi : 10.1111/jdv.17383

Volume 35, Issue 10 p. e676-e679

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Effectiveness of Omalizumab in Patients with Chronic Inducible Urticaria: real-life experience from two UCARE centres

P. K. Can,A. Salman,S. Ho?gören-Tekin,E. Kocatürk

doi : 10.1111/jdv.17385

Volume 35, Issue 10 p. e679-e682

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Activity of nadifloxacin and three other antimicrobial agents against Cutibacterium acnes isolated from patients with acne vulgaris

P. Nenoff,D. Koch,C. Krüger,C. Neumeister,M.R. Götz,U. Schwantes,R.-H. Bödeker,C. Borelli

doi : 10.1111/jdv.17386

Volume 35, Issue 10 p. e682-e684

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Morphea-like changes in the setting of cancer immunotherapy

C. De Simone,M. Mannino,P. Sollena,F. Deilhes,V. Sibaud,K. Peris

doi : 10.1111/jdv.17388

Volume 35, Issue 10 p. e684-e685

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Real-world experience with risankizumab in patients with plaque psoriasis: a retrospective study

M. Mehta,A. O’Toole,M. Gooderham

doi : 10.1111/jdv.17410

Volume 35, Issue 10 p. e685-e688

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Sutton’s naevi as a pitfall for reflectance confocal microscopy: marked inflamed naevi could not be suitable for teleconfocal examination

A. Brugués,S. Ribero,A. Barreiro,S. Bassoli,A.P. García,C. Longo,S. Segura,L. Alós,J. Malvehy,S. Puig,C. Carrera

doi : 10.1111/jdv.17412

Volume 35, Issue 10 p. e688-e690

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Expanding the clinical spectrum of mosaic BRAF skin phenotypes

A. Sorlin,V. Carmignac,J. Amiel,O. Boccara,S. Fraitag,A. Maruani,M. Theiler,L. Weibel,Y. Duffourd,C. Philippe,C. Thauvin-Robinet,L. Faivre,J.-B. Rivière,P. Vabres,P. Kuentz

doi : 10.1111/jdv.17413

Volume 35, Issue 10 p. e690-e693

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A non-healing ulcer caused by a retained fish spine

J. Young,S. Mizzi,L. Mercieca,M.J. Boffa

doi : 10.1111/jdv.17416

Volume 35, Issue 10 p. e693-e695

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Two examples of Renbök phenomenon in dermatophytosis sparing congenital nevi

R. Happle,U. Wollina,S.B. Verma

doi : 10.1111/jdv.17417

Volume 35, Issue 10 p. e695-e697

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Dermatology textbooks in Scandinavia should prepare medical students for ethnic diversity

A. Elyas,F. Dalgard,Å. Svensson

doi : 10.1111/jdv.17418

Volume 35, Issue 10 p. e697-e698

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