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A 21-Year-Old Woman With Joint Pain and Skin Ulceration
Sarah French,Ursula E. Lang,Mary Margaretten
doi : 10.1002/acr.24141
Volume 73, Issue 11 p. 1553-1560
Access and Cost-Related Nonadherence to Prescription Medications Among Lupus Patients and Controls: The Michigan Lupus Epidemiology and Surveillance Program
Deeba Minhas,Wendy Marder,Sioban Harlow,Afton L. Hassett,Suzanna M. Zick,Caroline Gordon,Kamil E. Barbour,Charles G. Helmick,Lu Wang,Jiha Lee,Amrita Padda,W. Joseph McCune,Emily C. Somers
doi : 10.1002/acr.24397
Volume 73, Issue 11 p. 1561-1567
Medication access and adherence are important determinants of health outcomes. We investigated factors associated with access and cost-related nonadherence to prescriptions in a population-based cohort of systemic lupus erythematosus (SLE) patients and controls.
Patient Perspective on Using Digital Resources to Address Unmet Needs in Systemic Lupus Erythematosus
Jennifer H. Ra,Jerik Leung,Elizabeth A. Baker,Alfred H. J. Kim
doi : 10.1002/acr.24399
Volume 73, Issue 11 p. 1568-1576
The clinical variability of systemic lupus erythematosus (SLE) caused by the unpredictability of flares contributes to patients experiencing a diminished sense of social support. Digital health interventions (DHIs) have the potential to improve patients’ social support but have yet to be studied extensively in SLE. Our objective was to assess general and SLE-specific internet usage as well as specific suggestions for SLE-related digital resources and tools among patients with SLE at the Washington University Lupus Clinic.
Cachexia in Systemic Lupus Erythematosus: Risk Factors and Relation to Disease Activity and Damage
George Stojan,Jessica Li,Amaya Wittmaack,Michelle Petri
doi : 10.1002/acr.24395
Volume 73, Issue 11 p. 1577-1582
Cachexia is a disorder characterized by involuntary weight loss in addition to loss of homeostatic control of both energy and protein balance. Despite an abundance of data from other inflammatory diseases, cachexia in systemic lupus erythematosus (SLE) remains a largely undescribed syndrome. The present study was undertaken to define the prevalence of cachexia in SLE and to identify the main factors that place patients at risk of developing cachexia.
Associations Between Smoking and Systemic Lupus Erythematosus–Related Cytokines and Chemokines Among US Female Nurses
Jill Hahn,Cianna Leatherwood,Susan Malspeis,Xinyi Liu,Bing Lu,Andrea L. Roberts,Jeffrey A. Sparks,Elizabeth W. Karlson,Candace H. Feldman,Melissa E. Munroe,Judith A. James,Laura D. Kubzansky,Karen H. Costenbader
doi : 10.1002/acr.24370
Volume 73, Issue 11 p. 1583-1589
Smoking has been associated with increased systemic lupus erythematosus (SLE) risk, but the biologic basis for this association is unknown. Our objective was to investigate whether women’s smoking was positively associated with SLE-associated proinflammatory chemokines/cytokines (stem cell factor [SCF], B lymphocyte stimulator [BLyS], interferon-?–inducible 10-kd protein [IP-10], and interferon-?); or negatively associated with antiinflammatory cytokine interleukin-10 (IL-10); and whether associations were modified by SLE-related autoantibody status.
Differences in Capacity of High-Density Lipoprotein Cholesterol Efflux Between Patients With Systemic Lupus Erythematosus and Rheumatoid Arthritis
Juan C. Quevedo-Abeledo,Hiurma Sánchez-Pérez,Beatriz Tejera-Segura,Laura de Armas-Rillo,Estefanía Armas-González,José David Machado,Miguel A. González-Gay,Federico Díaz-González,Iván Ferraz-Amaro
doi : 10.1002/acr.24407
Volume 73, Issue 11 p. 1590-1596
Cholesterol efflux capacity (CEC) is the ability of high-density lipoprotein (HDL) cholesterol to accept cholesterol from macrophages. Lipid profiles and CEC appear to be altered in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) due to disease activity and inflammation. CEC has been linked to cardiovascular events in the general population and to subclinical atherosclerosis in SLE and RA patients. The aim of this study was to establish whether CEC varies between patients with SLE and those with RA.
Variability in Glucocorticoid Prescribing for Rheumatoid Arthritis and the Influence of Provider Preference on Long-Term Use of Glucocorticoids
Michael D. George,Joshua F. Baker,Beth Wallace,Lang Chen,Qufei Wu,Fenglong Xie,Huifeng Yun,Jeffrey R. Curtis
doi : 10.1002/acr.24382
Volume 73, Issue 11 p. 1597-1605
Glucocorticoids are recommended for short-term use in rheumatoid arthritis (RA), but many patients continue receiving long-term therapy. We evaluated the variability in glucocorticoid prescribing across rheumatologists to inform interventions to limit long-term glucocorticoid use to the lowest dose necessary.
Systematic Literature Review of Residual Symptoms and an Unmet Need in Patients With Rheumatoid Arthritis
Kaleb Michaud,Janet Pope,Mart van de Laar,Jeffrey R. Curtis,Carol Kannowski,Sarah Mitchell,Judith Bell,Jennifer Workman,Jim Paik,Anabela Cardoso,Peter C. Taylor
doi : 10.1002/acr.24369
Volume 73, Issue 11 p. 1606-1616
To evaluate the nature and burden of residual disease in rheumatoid arthritis (RA) in patients who meet treatment targets. Second, for those who did not meet targets, to evaluate how much is due to patient symptoms.
Systematic Review of the Evolution of Health-Economic Evaluation Models of Osteoarthritis
Ting Zhao,Hasnat Ahmad,Barbara de Graaff,Qing Xia,Tania Winzenberg,Dawn Aitken,Andrew J. Palmer
doi : 10.1002/acr.24410
Volume 73, Issue 11 p. 1617-1627
To comprehensively synthesize the evolution of health-economic evaluation models (HEEMs) of all osteoarthritis (OA) interventions, including preventions, core treatments, adjunct nonpharmacologic interventions, pharmacologic interventions, and surgical treatments.
Two-Year Changes in Magnetic Resonance Imaging Features and Pain in Thumb Base Osteoarthritis
Sjoerd van Beest,Herman M. Kroon,Monique Reijnierse,Frits R. Rosendaal,Margreet Kloppenburg,Féline P. B. Kroon
doi : 10.1002/acr.24355
Volume 73, Issue 11 p. 1628-1637
To investigate the two-year course of pain and osteoarthritic features on magnetic resonance imaging (MRI) in the thumb base.
Understanding the Association Between Osteoarthritis and Social Participation: The Canadian Longitudinal Study on Aging
Anthony V. Perruccio,Calvin Yip,J. Denise Power,Mayilee Canizares,Monique A. M. Gignac,Elizabeth M. Badley
doi : 10.1002/acr.24366
Volume 73, Issue 11 p. 1638-1647
The focus on disability in osteoarthritis (OA) has largely been on the ability to perform specific activities, which neglects the greater implications for social participation. We investigated the association between OA and social participation, considering activity limitations and instrumental supports as intervening variables in the association.
Patterns and Correlates of Self-Management Strategies for Osteoarthritis-Related Pain Among Older Non-Hispanic Black and Non-Hispanic White Adults
Alisa J. Johnson,Kimberly T. Sibille,Josue Cardoso,Ellen L. Terry,Keesha L. Powell-Roach,Burel Goodin,Roland Staud,David Redden,Roger B. Fillingim,Staja Q. Booker
doi : 10.1002/acr.24396
Volume 73, Issue 11 p. 1648-1658
Knee osteoarthritis (OA) is a leading source of pain and disability among older adults. Self-management (SM) strategies are recommended to manage OA symptoms. Sociodemographic and clinical characteristics, along with other factors, may influence SM utilization rate. This study sought to examine the prevalence and correlates of SM use for pain among non-Hispanic Black patients (NHB) and non-Hispanic White patients (NHW) older adults with or at risk for knee OA.
Relationship Between Magnetic Resonance Imaging Features and Knee Pain Over Six Years in Knees Without Radiographic Osteoarthritis at Baseline
Karin Magnusson,Aleksandra Turkiewicz,Jaanika Kumm,Fan Zhang,Martin Englund
doi : 10.1002/acr.24394
Volume 73, Issue 11 p. 1659-1666
To explore whether magnetic resonance imaging (MRI) features suggestive of knee osteoarthritis (OA) are associated with presence of knee pain in possible early-stage OA development.
Associations Between Cadence and Knee Loading in Patients With Knee Osteoarthritis
Harvi F. Hart,Trevor B. Birmingham,Codie A. Primeau,Ryan Pinto,Kristyn Leitch,J. Robert Giffin
doi : 10.1002/acr.24400
Volume 73, Issue 11 p. 1667-1671
To test the hypothesis that higher walking cadence is associated with lower knee loading, while controlling for walking speed, in patients with medial compartment tibiofemoral osteoarthritis (OA).
Immunomodulatory Medication Use in Newly Diagnosed Youth With Systemic Lupus Erythematosus
Alaina Davis,Joyce Chang,Sarah Shapiro,Marisa Klein-Gitelman,Jennifer Faerber,Hannah Katcoff,Zuleyha Cidav,David S. Mandell,Andrea Knight
doi : 10.1002/acr.24392
Volume 73, Issue 11 p. 1672-1677
To examine glucocorticoid-sparing immunomodulatory medication use in youth with systemic lupus erythematosus (SLE) during their first year of care.
Clinical Scenario and Long-Term Outcome of Childhood Takayasu Arteritis Undergoing 121 Endovascular Interventions: A Large Cohort Over a Fifteen-Year Period
Luyun Fan,Lirui Yang,Dongmei Wei,Wenjun Ma,Ying Lou,Lei Song,Jin Bian,Huimin Zhang,Jun Cai
doi : 10.1002/acr.24387
Volume 73, Issue 11 p. 1678-1688
Evidence-based studies on endovascular approaches for childhood Takayasu arteritis (TAK) are limited. Our objective was to present the largest current real-world scenario for patients with childhood TAK undergoing interventions and their postinterventional outcomes.
Significant Decline in the Incidence of Behçet’s Disease in South Korea: A Nationwide Population-Based Study (2004–2017)
Jae-Bum Jun,Hyun Jung Kim,Sayada Zartasha Kazmi,Taeuk Kang,Kyoung-Beom Kim,Min Ji Kang,Hyeong Sik Ahn
doi : 10.1002/acr.24408
Volume 73, Issue 11 p. 1689-1696
Long-term population-based data on change in the incidence of Behçet’s disease (BD) are scarce, although a possible decline has been reported. The present study was undertaken to investigate the incidence, survival, and mortality of BD patients from 2004 to 2017 in the Republic of Korea.
Defining Symptomatic Radiographic Foot Osteoarthritis: Comment on the Article by Golightly and Gates
Edward Roddy,Martin J. Thomas,Hylton B. Menz,Shannon Munteanu,Michelle Marshall,George Peat
doi : 10.1002/acr.24380
Volume 73, Issue 11 p. 1697-1698
Efficacy and Safety of Pharmacologic Interventions in Patients Experiencing a Gout Flare: A Systematic Review and Network Meta-analysis. Comment on the Article by Zeng et al
Donald R. Miller
doi : 10.1002/acr.24755
Volume 73, Issue 11 p. 1698-1699
Reply
Linan Zeng,Tuhina Neogi,John D. Fitzgerald,Nicola Dalbeth,Ted R. Mikuls,Romina Brignardello-Petersen
doi : 10.1002/acr.24753
Volume 73, Issue 11 p. 1699-1699
