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CLINICAL SIGNIFICANCE OF RETINAL VASCULAR OCCLUSION IN MOYAMOYA DISEASE: Case Series and Systematic Review

Seong, Hyo Jin MD*; Lee, Ji Hwan MD, PhD*; Heo, Ji Hoe MD, PhD†; Kim, Dong Seok MD, PhD‡; Kim, Yong Bae MD, PhD‡; Lee, Christopher Seungkyu MD, PhD*

doi : 10.1097/IAE.0000000000003181

September 2021 - Volume 41 - Issue 9 - p 1791-1798

Although moyamoya disease primarily affects the carotid artery in the ophthalmic artery bifurcation area, retinal vascular abnormalities in moyamoya disease have rarely been reported. The purpose of this report is to describe clinical findings of patients with retinal vascular occlusion in patients with moyamoya disease and present its clinical significance.

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OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY ASSESSMENT OF THE DIABETIC MACULA: A Comparison Study Among Different Algorithms

Borrelli, Enrico MD, FEBO*; Sacconi, Riccardo MD, FEBO*; Parravano, Mariacristina MD†; Costanzo, Eliana MD†; Querques, Lea MD*; Battista, Marco MD*; Grosso, Domenico MD*; Giorno, Paola MD†; Bandello, Francesco MD, FEBO*; Querques, Giuseppe MD, PhD*

doi : 10.1097/IAE.0000000000003145

September 2021 - Volume 41 - Issue 9 - p 1799-1808

To assess the impact of histogram adjustments and binarization thresholding selection on quantitative measurements of diabetic macular ischemia using optical coherence tomography angiography (OCTA).

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QUANTITATIVE ANALYSIS OF CHORIOCAPILLARIS ALTERATIONS IN SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN DIABETIC PATIENTS

Loria, Olivier MD*; Kodjikian, Laurent MD, PhD*,†; Denis, Philippe MD, PhD*; Vartin, Christine MD*; Dimassi, Sarra MD‡; Gervolino, Lucas§; Maignan, Antoine§; Kermarrec, Ronan§; Chambard, Claudine*,§; Pradat, Pierre PhD¶; Mathis, Thibaud MD, PhD*,†

doi : 10.1097/IAE.0000000000003102

September 2021 - Volume 41 - Issue 9 - p 1809-1818

To evaluate quantitative alterations of the choriocapillaris in swept-source optical coherence tomography angiography in diabetic patients.

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CHORIOCAPILLARIS FLOW IMPAIRMENT IN TYPE 3 MACULAR NEOVASCULARIZATION: A Quantitative Analysis Using Swept-Source Optical Coherence Tomography Angiography

Le, Hoang Mai MD, MRes*,†; Souied, Eric H. MD, PhD*,‡; Querques, Giuseppe MD, PhD*,§; Colantuono, Donato MD*; Borrelli, Enrico MD§; Sacconi, Riccardo MD§; Amoroso, Francesca MD*; Capuano, Vittorio MD*; Jung, Camille MD, PhD‡; Miere, Alexandra MD, PhD*,¶

doi : 10.1097/IAE.0000000000003119

September 2021 - Volume 41 - Issue 9 - p 1819-1827

To quantitatively analyze choriocapillaris alterations using swept-source optical coherence tomography angiography in eyes presenting with Type 3 macular neovascularization (MNV) and to compare these alterations with eyes presenting with intermediate AMD (iAMD).

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EXTERNAL DRAINAGE OF SUBRETINAL FLUID DURING RHEGMATOGENOUS RETINAL DETACHMENT REPAIR

Belin, Peter J. MD*; Mundae, Rusdeep MD†; Tzu, Jonathan H. MD‡; Chang, Emmanuel MD, PhD‡; Parke, David W. III MD*

doi : 10.1097/IAE.0000000000003136

September 2021 - Volume 41 - Issue 9 - p 1828-1832

To describe the safety and efficacy of rhegmatogenous retinal detachment (RRD) repair with external drainage of subretinal fluid using a 28-gauge External Drainage and Depression device (Vortex Surgical, Chesterfield, MO).

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LATE PRESENTATION OF RETINAL DETACHMENT: CLINICAL FEATURES AND SURGICAL OUTCOMES

Anguita, Rodrigo MD; Roth, Janice MD; Makuloluwa, Achini MD; Shahid, Syed MD; Katta, Mohamed MD; Khalid, Hagar MD; Charteris, David G. FRCOphth

doi : 10.1097/IAE.0000000000003131

September 2021 - Volume 41 - Issue 9 - p 1833-1838

To describe and evaluate demographic, clinical features, prognostic factors, and rate of success of surgery and visual outcomes in patients with late presentation of retinal detachment.

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TEMPORAL CHANGES OF PARAFOVEAL MICROVASCULATURE AFTER EPIRETINAL MEMBRANE SURGERY: An Optical Coherence Tomography Angiography Study

Kim, Jongshin MD, PhD*,†; Park, Kyu Hyung MD, PhD*,†

doi : 10.1097/IAE.0000000000003132

September 2021 - Volume 41 - Issue 9 - p 1839-1850

To investigate whether the parafoveal capillary architecture predicts clinical course and visual outcomes after epiretinal membrane (ERM) surgery.

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COMPARISON OF SPECTRALIS AND CIRRUS OPTICAL COHERENCE TOMOGRAPHY FOR THE DETECTION OF INCOMPLETE AND COMPLETE RETINAL PIGMENT EPITHELIUM AND OUTER RETINAL ATROPHY

Corvi, Federico MD*,†,‡; Corradetti, Giulia MD*,†; Nittala, Muneeswar Gupta MPhil*; Velaga, Swetha Bindu BsOpt*; Haines, Jonathan L. PhD§; Pericak-Vance, Margaret Ann PhD¶; Stambolian, Dwight MD, PhD**; Sadda, SriniVas R. MD*,†

doi : 10.1097/IAE.0000000000003158

September 2021 - Volume 41 - Issue 9 - p 1851-1857

To evaluate and compare the detection of incomplete and complete retinal pigment epithelial and outer retinal atrophy (iRORA and cRORA) using Spectralis and Cirrus optical coherence tomography (OCT) devices.

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CHANGES IN THE CHOROIDAL THICKNESS AFTER MACULAR BUCKLING IN HIGHLY MYOPIC EYES

Tang, Ningning MD*,†; Zhao, Xiujuan MD, PhD*; Chen, Jing MD*; Liu, Bingqian MD, PhD*; Lu, Lin MD, PhD*

doi : 10.1097/IAE.0000000000003125

September 2021 - Volume 41 - Issue 9 - p 1858-1866

To assess changes in the choroidal thickness (CT) after macular buckling in eyes with high myopia.

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CORRELATION BETWEEN ATROPHY-TRACTION-NEOVASCULARIZATION GRADE FOR MYOPIC MACULOPATHY AND CLINICAL SEVERITY

Ruiz-Medrano, Jorge MD, PhD*; Flores-Moreno, Ignacio MD, PhD*; Ohno-Matsui, Kyoko MD, PhD†; Cheung, Chui Ming Gemmy MD, PhD‡; Silva, Rufino MD, PhD§,¶,**,††; Ruiz-Moreno, José M. MD, PhD*,‡‡,§§,¶¶

doi : 10.1097/IAE.0000000000003129

September 2021 - Volume 41 - Issue 9 - p 1867-1873

To assess the reliability of the atrophy-traction-neovascularization (ATN) classification in patients with pathologic myopia (PM) and its correlation with best-corrected visual acuity (BCVA).

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EVALUATION OF THE EFFICACY OF POSTERIOR SCLERAL CONTRACTION IN THE TREATMENT OF MACULAR HOLE WITH RETINAL DETACHMENT IN HIGH MYOPIA

Ye, Jie PhD; Wu, Yue MD; Zhu, Shuangqian MD; Dong, Liang MD; Qu, Jia MD; Lu, Fan OD; Xue, Anquan MD

doi : 10.1097/IAE.0000000000003126

September 2021 - Volume 41 - Issue 9 - p 1874-1882

To evaluate efficacy of posterior scleral contraction for macular hole with retinal detachment in high myopia.

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EIGHTEEN-MONTH RESULTS OF INTRAVITREAL ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR ON VISION AND MICROCIRCULATION IN RADIATION MACULOPATHY

Eandi, Chiara M. MD, PhD*,†; Polito, Maria S. MD*; Schalenbourg, Ann MD*; Zografos, Leonidas MD*

doi : 10.1097/IAE.0000000000003105

September 2021 - Volume 41 - Issue 9 - p 1883-1891

To evaluate 18 months' results of a strict anti–vascular endothelial growth factor protocol for radiation maculopathy following proton therapy in choroidal melanoma.

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ASSOCIATIONS WITH RECURRENCE OF MACULAR EDEMA IN BRANCH RETINAL VEIN OCCLUSION AFTER THE DISCONTINUATION OF ANTI VASCULAR ENDOTHELIAL GROWTH FACTOR

Lee, Geun Woo MD*,†; Kang, Se Woong MD, PhD†; Kang, Min Chae MD†; Kim, Sang Jin MD, PhD†; Kim, Yoon Young MD, PhD*

doi : 10.1097/IAE.0000000000003118

September 2021 - Volume 41 - Issue 9 - p 1892-1900

To identify factors predicting the recurrence of macular edema after the discontinuation of intravitreal antivascular endothelial growth factor injection in patients with branch retinal vein occlusion.

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SINGLE INJECTION RESPONSE TO ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS IN PATIENTS WITH WET AGE-RELATED MACULAR DEGENERATION: Incidence and Characteristics

Bilgic, Alper MD*; Kodjikian, Laurent MD†,‡; Mathis, Thibaud MD†,‡; Sudhalkar, Aditya A. MD*,§,¶; Vasavada, Shail A. DNB¶; Bhojwani, Deepak M. MS¶

doi : 10.1097/IAE.0000000000003106

September 2021 - Volume 41 - Issue 9 - p 1901-1910

To determine the incidence of complete resolution of choroidal neovascular membrane-associated exudation with a single antivascular endothelial growth factor injection in treatment-naive wet age-related macular degeneration patients and its associated characteristics.

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EFFICACY AND SAFETY OF INTRAVITREAL AFLIBERCEPT USING A TREAT-AND-EXTEND REGIMEN FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: The ARIES Study: A Randomized Clinical Trial

Mitchell, Paul MD, PhD*; Holz, Frank G. FEBO, FARVO†; Hykin, Philip FRCS, FRCOphth‡; Midena, Edoardo MD, PhD§; Souied, Eric MD, PhD¶; Allmeier, Helmut PhD**; Lambrou, George MD, PhD**; Schmelter, Thomas PhD††; Wolf, Sebastian MD, PhD‡‡; on behalf of the ARIES study investigators

doi : 10.1097/IAE.0000000000003128

September 2021 - Volume 41 - Issue 9 - p 1911-1920

Treating neovascular age-related macular degeneration with intravitreal aflibercept treat-and-extend (T&E) can reduce treatment burden. ARIES assessed whether intravitreal aflibercept early-start T&E was noninferior to late-start T&E.

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SENSITIVITY AND SPECIFICITY OF MULTISPECTRAL IMAGING FOR POLYPOIDAL CHOROIDAL VASCULOPATHY

Ma, Feiyan MD*; Yuan, Mingzhen MD†,‡; Kozak, Igor MD§; Zhang, Qing MD†,‡; Chen, Youxin MD†,‡

doi : 10.1097/IAE.0000000000003130

September 2021 - Volume 41 - Issue 9 - p 1921-1929

To evaluate the sensitivity and specificity of multispectral imaging (MSI), a noninvasive imaging technique composed of a series of monochromatic scanning light, for polypoidal choroidal vasculopathy (PCV).

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OUTER RETINAL TUBULATION MAY RESULT FROM FIBROSED TYPE 2 NEOVASCULARIZATION: Clinical Observations and Model of Pathogenesis

Janse van Rensburg, Ernst MD*; Ryu, Christina L. MD*,†,‡; Rampakakis, Emmanouil PhD§; Vila, Natalia MD, PhD*,¶; Chan, Errol W. MD*,**; Chen, John C. MD*

doi : 10.1097/IAE.0000000000003127

September 2021 - Volume 41 - Issue 9 - p 1930-1939

To investigate the role of Type 2 macular neovascularization with subsequent subretinal fibrosis in the pathogenesis of outer retinal tubulation (ORT).

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CORRELATION OF OUTER RETINAL TUBULATIONS AND CHORIOCAPILLARIS FLOW SIGNAL DEFICITS SURROUNDING GEOGRAPHIC ATROPHY

Haensli, Christof MD*,†; Sugiura, Yoshimi MD‡,§; Freund, K Bailey MD‡,¶,**; Zweifel, Sandrine A. MD*,†

doi : 10.1097/IAE.0000000000003135

September 2021 - Volume 41 - Issue 9 - p 1940-1947

To evaluate and compare paralesional and perilesional choriocapillaris vascular impairment in eyes with geographic atrophy with and without outer retinal tubulations (ORT).

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NEGATIVE VESSEL REMODELING IN STARGARDT DISEASE QUANTIFIED WITH VOLUME-RENDERED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

Reich, Michael MD*; Dreesbach, Michelle MD*; Boehringer, Daniel MD*; Schottenhamml, Julia MA†; Gehring, Esteban MSc‡; Scholl, Hendrik P. N. MD‡,§; Inglin, Nadja EFZ‡; Agostini, Hansjuergen MD*; Reinhard, Thomas MD*; Lagrèze, Wolf A. MD*; Spaide, Richard F. MD¶; Lange, Clemens MD, PhD, FEBO*; Maloca, Peter M. MD‡,§,**

doi : 10.1097/IAE.0000000000003110

September 2021 - Volume 41 - Issue 9 - p 1948-1957

To quantify retinal vasculature changes in Stargardt disease1 (STGD1) with volume-rendered optical coherence tomography angiography.

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STRUCTURAL PATHOLOGY AFTER RETINAL DETACHMENT: Multicolor Confocal Scanning Laser Ophthalmoscopy Versus Color Fundus Photography

Thomseth, Vilde M. MD*,†; Ushakova, Anastasia PhD‡; Krohn, Jørgen MD, PhD§,¶; Utheim, Tor P. MD, PhD*,†,§; Austeng, Dordi MD, PhD**,††; Fossen, Kristian MD‡‡; Varhaug, Pål MD¶; Malmin, Agni MD*; Skeiseid, Liliane MD*; Tharaldsen, Ane MD*; Lindtjørn, Birger MD*; Johannesen, Henrik MD*; Juul, Jens MD*; Forsaa, Vegard A. MD, PhD*,†

doi : 10.1097/IAE.0000000000003113

September 2021 - Volume 41 - Issue 9 - p 1958-1965

To compare pathology detection using multicolor confocal scanning laser ophthalmoscopy with color fundus photography following macula-off rhegmatogenous retinal detachment.

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CONCOMITANT MUTATIONS IN INHERITED RETINAL DYSTROPHIES: Why the Reproductive and Therapeutic Counseling Should Be Addressed Cautiously

Rodríguez-Muñoz, Ana PharmD, PhD*,†,‡; García-Bohórquez, Belén MSc*,†; Udaondo, Patricia MD, PhD§; Hervás-Ontiveros, Ana MD§; Salom, David MD, PhD*,‡,¶; Aller, Elena PhD*,†,‡,**; Jaijo, Teresa PhD*,†,‡,**; García-García, Gema PhD*,†,‡; Millán, José PhD*,†,‡

doi : 10.1097/IAE.0000000000003103

September 2021 - Volume 41 - Issue 9 - p 1966-1975

To highlight the challenge of correct reproductive and therapeutic counseling in complex pedigrees with different inherited retinal dystrophies (IRD).

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INTRAVITREAL RANIBIZUMAB TREATMENT FOR ADVANCED FAMILIAL EXUDATIVE VITREORETINOPATHY WITH HIGH VASCULAR ACTIVITY

Lyu, Jiao MD, PhD; Zhang, Qi MD; Xu, Yu MD, PhD; Zhang, Xiang MD; Fei, Ping MD, PhD; Zhao, Peiquan MD, PhD

doi : 10.1097/IAE.0000000000003122

September 2021 - Volume 41 - Issue 9 - p 1976-1985

To determine the efficacy of intravitreal ranibizumab (IVR) treatment for advanced familial exudative vitreoretinopathy with high vascular activity.

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SURGICAL RETINAL EXPLANTS AS A SOURCE OF RETINAL PROGENITOR CELLS

Too, Lay Khoon PhD*; Shen, Weiyong MD, PhD*; Mammo, Zaid MD, FRCSC†; Osaadon, Perach MD†; Gillies, Mark C. MB BS, PhD, FRANZCO*,†; Simunovic, Matthew P. MB BChir PhD FRANZCO*,†

doi : 10.1097/IAE.0000000000003137

September 2021 - Volume 41 - Issue 9 - p 1986-1993

To describe the novel observation of spontaneously migrating retinal cells from living donor surgical retinal explants that express progenitor cell markers in the absence of exogenous growth factors.

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Diagnostic and Therapeutic Challenges

Nagaradh, Krishna Drs.; Gokarn, Prarthana; Mruthyunjaya, Prithvi

doi : 10.1097/IAE.0000000000003041

September 2021 - Volume 41 - Issue 9 - p 1994-1998

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Diagnostic and Therapeutic Challenges

Scoles, Drew Drs.; Bracha, Peter; S. Aleman, Tomas; Bhatt, Nirali; Cunningham, Emmett T.

doi : 10.1097/IAE.0000000000003042

September 2021 - Volume 41 - Issue 9 - p 1999-2003

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A NOVEL DO-IT-YOURSELF ANTIFOGGING DEVICE FOR VITREORETINAL SURGERIES

Baskaran, Prabu MS, DNB*; Rajendran, Anand DNB*; Sindal, Manavi MS†; Lobo, Simmone MS*; Jain, Bhavik DNB*

doi : 10.1097/IAE.0000000000003219

September 2021 - Volume 41 - Issue 9 - p 2004-2006

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Multimodal Imaging of a Thrombosed Optic Disk Macroaneurysm

Bastons-Compta, Clara MD; Lorenzo, Daniel PhD; Caminal, José M. PhD

doi : 10.1097/IAE.0000000000003248

September 2021 - Volume 41 - Issue 9 - p e49-e50

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Coffee Bean–Like Hemorrhages in Tuberculosis Associated Multifocal Choroiditis

Patel, Anamika MD; Pathengay, Avinash FRCS; Panchal, Bhavik DNB

doi : 10.1097/IAE.0000000000003268

September 2021 - Volume 41 - Issue 9 - p e51-e52

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Correspondence

Fang, Xiang MD, PhD*; Cui, Tao MD, PhD†,‡; Qiu, Jianqing MD§; Zhang, Wenli MD, PhD*; Duan, Hong MD, PhD*

doi : 10.1097/IAE.0000000000003172

September 2021 - Volume 41 - Issue 9 - p e53

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Reply

Fujita, Ai MD; Kataoka, Keiko MD, PhD; Takeuchi, Jun MD; Nakano, Yuyako MD; Horiguchi, Etsuyo MD; Kaneko, Hiroki MD, PhD; Ito, Yasuki MD, PhD; Terasaki, Hiroko MD, PhD

doi : 10.1097/IAE.0000000000003173

September 2021 - Volume 41 - Issue 9 - p e54

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Correspondence

Achiron, Romi Noy MD*; Achiron, Asaf MD*,†; Tuuminen, Raimo MD, PhD‡,§

doi : 10.1097/IAE.0000000000003184

September 2021 - Volume 41 - Issue 9 - p e55-e56

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Heier, Jeffrey S. MD*; Singh, Rishi P. MD†; Wykoff, Charles C. MD, PHD‡; Csaky, Karl G. MD, PHD§; Lai, Timothy Y. Y. MD, FRCS, FRCOPHTH¶; Loewenstein, Anat MD*,*; Schlottmann, Patricio G. MD††; Paris, Liliana P. MD, PHD‡‡; Westenskow, Peter D. PHD‡‡; Quezada-Ruiz, Carlos MD§§,¶¶

doi : 10.1097/IAE.0000000000003183

September 2021 - Volume 41 - Issue 9 - p e56-e58

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Correspondence

ÇALI?KAN, Sinan MD, FEBO; Y?ld?z, Zuhal MD

doi : 10.1097/IAE.0000000000003186

September 2021 - Volume 41 - Issue 9 - p e58

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Nowroozzadeh, M. Hossein MD*; Eslami, Jamshid PhD†; Kalashipour, Farid MSc‡; Jamali, Hossein MD*

doi : 10.1097/IAE.0000000000003187

September 2021 - Volume 41 - Issue 9 - p e58-e59

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Correspondence

Gioia, Marco MD*; De Bernardo, Maddalena MD, PhD*; Capasso, Luigi MD, PhD†; Rosa, Nicola MD*

doi : 10.1097/IAE.0000000000003188

September 2021 - Volume 41 - Issue 9 - p e59-e60

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Reply

Kim, Jae Hui

doi : 10.1097/IAE.0000000000003189

September 2021 - Volume 41 - Issue 9 - p e60-e61

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Correspondence

Kushwah, Shiva DOMS*; Dave, Prachi A. MS, DNB, FICO, MRCOph†

doi : 10.1097/IAE.0000000000003197

September 2021 - Volume 41 - Issue 9 - p e61

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Liu, Pei-Kang MD*,†,‡,§; Chang, Yo-Chen MD*,†; Chuang, Cheng-Hao MD¶; Tsai, Ming-Ju MD, PhD†,¶,**,††

doi : 10.1097/IAE.0000000000003198

September 2021 - Volume 41 - Issue 9 - p e61-e64

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Correspondence

Muralidhar, Alankrita DNB ophthalmology; Saxena, Rushil Kumar DNB ophthalmology; Agarwal, Manisha DNB ophthalmology

doi : 10.1097/IAE.0000000000003211

September 2021 - Volume 41 - Issue 9 - p e64-e65

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Reply

Ozsaygili, Cemal MD, FEBO; Duru, Necati MD, FEBO

doi : 10.1097/IAE.0000000000003212

September 2021 - Volume 41 - Issue 9 - p e65-e66

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Correspondence

Ogawa, Gregory S. H. MD*; Snyder, Michael E. MD†

doi : 10.1097/IAE.0000000000003245

September 2021 - Volume 41 - Issue 9 - p e66-e67

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Bonnell, Alyssa C. MD*; Mantopoulos, Dimosthenis MD, PhD†; Fine, Howard F. MD, MHSc‡,§; Shah, Sumit P. MD‡,§; Wheatley, H. Matthew MD‡,§; Prenner, Jonathan L. MD‡,§

doi : 10.1097/IAE.0000000000003246

September 2021 - Volume 41 - Issue 9 - p e67-e68

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Correspondence

Shukla, Dhananjay MS, MAMS

doi : 10.1097/IAE.0000000000003251

September 2021 - Volume 41 - Issue 9 - p e68-e69

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Baumann, Carmen MD, FEBO; El-Faouri, Muhannd MD, FICO, FRCS Glasg; Ivanova, Tsveta MD, PhD; Patton, Niall MB, ChB, MD, FRCOphth; Ch'ng, Soon W. FRCOphth; Dhawahir-Scala, Felipe E. FRCSEd, LMS; Jalil, Assad MBBS, FRCOphth

doi : 10.1097/IAE.0000000000003252

September 2021 - Volume 41 - Issue 9 - p e69-e70

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Correspondence

Gioia, Marco MD*; De Bernardo, Maddalena MD, PhD*; Capasso, Luigi MD, PhD†; Rosa, Nicola MD*

doi : 10.1097/IAE.0000000000003257

September 2021 - Volume 41 - Issue 9 - p e70

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Reply

Song, Ji Hun MD, PhD; Moon, Ka Young MD; Choi, Shin Young MD

doi : 10.1097/IAE.0000000000003258

September 2021 - Volume 41 - Issue 9 - p e70-e71

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Correspondence

Soh, Yu Qiang MBBS*; Hoang, Quan V. MD, PhD†,‡,§; Jung, Jesse J. MD¶,**

doi : 10.1097/IAE.0000000000003269

September 2021 - Volume 41 - Issue 9 - p e71-e72

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Reply

Ramtohul, Prithvi MD*; Freund, K. Bailey MD†,‡

doi : 10.1097/IAE.0000000000003270

September 2021 - Volume 41 - Issue 9 - p e72-e74

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