JAMA - Journal of the American Medical Association




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Effect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal SymptomsA Randomized Clinical Trial

Fiona G. Li, MD1; Sarah Maheux-Lacroix, PhD1; Rebecca Deans, PhD1; Erin Nesbitt-Hawes, PhD1; Aaron Budden, BMed1; Kimberly Nguyen, MD1; Claire Y. Lim1; Sophia Song, MD1; Lalla McCormack, MBChB1; Stephen D. Lyons, PhD1; Eva Segelov, PhD2; Jason A. Abbott, PhD1

doi : 10.1001/jama.2021.14892

JAMA. 2021;326(14):1381-1389

Postmenopausal vaginal symptoms are common and frequently detrimental to a woman’s quality of life. Fractional carbon dioxide vaginal laser is increasingly offered as a treatment, but the efficacy remains unproven.

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Surveillance for Adverse Events After COVID-19 mRNA Vaccination

Nicola P. Klein, MD, PhD1; Ned Lewis, MPH1; Kristin Goddard, MPH1; Bruce Fireman, MA1; Ousseny Zerbo, PhD1; Kayla E. Hanson, MPH2; James G. Donahue, DVM, PhD2; Elyse O. Kharbanda, MD, MPH3; Allison Naleway, PhD4; Jennifer Clark Nelson, PhD5; Stan Xu, PhD6; W. Katherine Yih, PhD, MPH7; Jason M. Glanz, PhD8,9; Joshua T. B. Williams, MD10,11; Simon J. Hambidge, MD, PhD10,11; Bruno J. Lewin, MD6; Tom T. Shimabukuro, MD, MPH, MBA12; Frank DeStefano, MD, MPH12; Eric S. Weintraub, MPH12

doi : 10.1001/jama.2021.15072

JAMA. 2021;326(14):1390-1399

Safety surveillance of vaccines against COVID-19 is critical to ensure safety, maintain trust, and inform policy.

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Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021

Jefferson M. Jones, MD, MPH1; Mars Stone, PhD2; Hasan Sulaeman, MS2; Rebecca V. Fink, MPH3; Honey Dave, MS2; Matthew E. Levy, PhD3; Clara Di Germanio, PhD2; Valerie Green, MS4; Edward Notari, MPH5; Paula Saa, PhD6; Brad J. Biggerstaff, PhD1; Donna Strauss, MS7; Debra Kessler, MS7; Ralph Vassallo, MD2; Rita Reik, MS8; Susan Rossmann, MD, PhD9; Mark Destree, MBA, MS10; Kim-Anh Nguyen, MD, PhD11; Merlyn Sayers, MBBCh, PhD12; Chris Lough, MD13; Daniel W. Bougie, PhD14; Megan Ritter, MD15; Gerardo Latoni, MD16; Billy Weales17; Stacy Sime, MS18; Jed Gorlin, MD, MBA19; Nicole E. Brown, PhD1; Carolyn V. Gould, MD, MSCR1; Kevin Berney, BA1; Tina J. Benoit, MPH1; Maureen J. Miller, MD, MPH1; Dane Freeman, PhD20; Deeksha Kartik20; Alicia M. Fry, MD, MPH1; Eduardo Azziz-Baumgartner, MD1; Aron J. Hall, DVM, MSPH1; Adam MacNeil, PhD1; Adi V. Gundlapalli, MD, PhD1; Sridhar V. Basavaraju, MD1; Susan I. Gerber, MD1; Monica E. Patton, MD1; Brian Custer, PhD, MPH2; Phillip Williamson, PhD4; Graham Simmons, PhD2; Natalie J. Thornburg, PhD1; Steven Kleinman, MD21; Susan L. Stramer, PhD, MS6; Jean Opsomer, PhD, MBA3; Michael P. Busch, MD, PhD2

doi : 10.1001/jama.2021.15161

JAMA. 2021;326(14):1400-1409

People who have been infected with or vaccinated against SARS-CoV-2 have reduced risk of subsequent infection, but the proportion of people in the US with SARS-CoV-2 antibodies from infection or vaccination is uncertain.

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Changes in Body Mass Index Among Children and Adolescents During the COVID-19 Pandemic

Susan J. Woolford, MD, MPH1; Margo Sidell, ScD2; Xia Li, MSc2; Veronica Else, RN, MSN3; Deborah R. Young, PhD2; Ken Resnicow, PhD4; Corinna Koebnick, PhD2

doi : 10.1001/jama.2021.15036

JAMA. 2021;326(14):1434-1436

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Prevalence of SARS-CoV-2 Antibodies From a National Serosurveillance of Kenyan Blood Donors, January-March 2021

Sophie Uyoga, PhD1; Ifedayo M. O. Adetifa, MD, PhD1; Mark Otiende, MSc1; Christine Yegon, BSc2; Ambrose Agweyu, MD, PhD1; George M. Warimwe, MRCVS, PhD1; J. Anthony G. Scott, MD1

doi : 10.1001/jama.2021.15265

JAMA. 2021;326(14):1436-1438

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Incorporation of Social Risk in US Preventive Services Task Force Recommendations and Identification of Key Challenges for Primary Care

Karina W. Davidson, PhD, MASc1; Alex H. Krist, MD, MPH2,3; Chien-Wen Tseng, MD, MPH, MSEE4,5; Melissa Simon, MD, MPH6; Chyke A. Doubeni, MD, MPH7; Alex R. Kemper, MD, MPH, MS8; Martha Kubik, PhD, RN9; Quyen Ngo-Metzger, MD, MPH10; Justin Mills, MD, MPH11; Amanda Borsky, DrPH, MPP11

doi : 10.1001/jama.2021.12833

JAMA. 2021;326(14):1410-1415

In its mission to improve health, the US Preventive Services Task Force (USPSTF) recognizes the strong relationship between a person’s health and social and economic circumstances as well as persistent inequities in health care delivery.

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Screening and Interventions for Social Risk FactorsTechnical Brief to Support the US Preventive Services Task Force

Michelle Eder, PhD1; Michelle Henninger, PhD1; Shauna Durbin, MPH2; Megan O. Iacocca, MS1; Allea Martin, MPH1; Laura M. Gottlieb, MD, MPH3; Jennifer S. Lin, MD, MCR1

doi : 10.1001/jama.2021.12825

JAMA. 2021;326(14):1416-1428

Evidence-based guidance is limited on how clinicians should screen for social risk factors and which interventions related to these risk factors improve health outcomes.

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A Middle Ground for Accelerated Drug Approval—Lessons From Aducanumab

Ezekiel J. Emanuel, MD, PhD1

doi : 10.1001/jama.2021.14861

JAMA. 2021;326(14):1367-1368

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Breakthrough Discovery in Protein Structure Prediction and the Promise of New Treatments

Anthony L. Komaroff, MD1

doi : 10.1001/jama.2021.15728

JAMA. 2021;326(14):1369-1370

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A Court Decision on “Skinny Labeling”Another Challenge for Less Expensive Drugs

Bryan S. Walsh, JD1,2; Doni Bloomfield, JD1,2; Aaron S. Kesselheim, MD, JD, MPH1,2

doi : 10.1001/jama.2021.0006

JAMA. 2021;326(14):1371-1372

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Our Best Judgment

Steven Radwany, MD1

doi : 10.1001/jama.2021.16348

JAMA. 2021;326(14):1373-1374

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Safety Surveillance of COVID-19 mRNA Vaccines Through the Vaccine Safety Datalink

Kimberly G. Blumenthal, MD, MSc1,2,3; Neelam A. Phadke, MD, MPH1,2; David W. Bates, MD, MSc2,4,5

doi : 10.1001/jama.2021.14808

JAMA. 2021;326(14):1375-1377

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Time for a “Pause” on the Use of Vaginal Laser

Marisa Adelman, MD1; Ingrid E. Nygaard, MD, MS1

doi : 10.1001/jama.2021.14809

JAMA. 2021;326(14):1378-1380

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Treatment of Women After Bilateral Salpingo-oophorectomy Performed Prior to Natural Menopause

Andrew M. Kaunitz, MD, NCMP1; Ekta Kapoor, MBBS, NCMP2; Stephanie Faubion, MD, MBA, NCMP3

doi : 10.1001/jama.2021.3305

JAMA. 2021;326(14):1429-1430

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Sodium Sulfate–Based Tablets (Sutab) for Colonoscopy Preparation

doi : 10.1001/jama.2021.3606

JAMA. 2021;326(14):1431-1432

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COVID-19 Testing Moves Out of the Clinic and Into the Home

Rita Rubin, MA

doi : 10.1001/jama.2021.15679

JAMA. 2021;326(14):1362-1364

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Delta Variant Linked With Spike in Youth Hospitalizations

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.16667

JAMA. 2021;326(14):1366

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HPV Vaccination Coverage Has Increased Among Adolescents

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.16574

JAMA. 2021;326(14):1366

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Moderna’s mRNA Vaccine for Seasonal Flu Enters Clinical Trials

Jennifer Abbasi

doi : 10.1001/jama.2021.17499

JAMA. 2021;326(14):1365

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India’s New COVID-19 DNA Vaccine for Adolescents and Adults Is a First

Jennifer Abbasi

doi : 10.1001/jama.2021.16625

JAMA. 2021;326(14):1365

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Vaccine-Induced SARS-CoV-2 Antibodies in Inflammatory Diseases

Jennifer Abbasi

doi : 10.1001/jama.2021.17500

JAMA. 2021;326(14):1365

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Your Ghost

Ellen Zhang, BA1

doi : 10.1001/jama.2021.11653

JAMA. 2021;326(14):1447

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The Spirit of Revolt

doi : 10.1001/jama.2020.18170

JAMA. 2021;326(14):1448

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Mechanical Ventilation

Kristin Walter, MD, MS1

doi : 10.1001/jama.2021.13084

JAMA. 2021;326(14):1452

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Continuous Glucose Monitoring Use and Access Disparities

Po-Jui Chu, MD1

doi : 10.1001/jama.2021.13481

JAMA. 2021;326(14):1438

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Continuous Glucose Monitoring Use and Access Disparities—Reply

Andrew J. Karter, PhD1; Lisa K. Gilliam, MD, PhD2; Richard Dlott, MD3

doi : 10.1001/jama.2021.13484

JAMA. 2021;326(14):1438

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Implantable vs Prolonged External Electrocardiographic Monitoring for Atrial Fibrillation Detection in Patients With Ischemic Stroke

Hiroshi Ito, MD1

doi : 10.1001/jama.2021.13487

JAMA. 2021;326(14):1439

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Implantable vs Prolonged External Electrocardiographic Monitoring for Atrial Fibrillation Detection in Patients With Ischemic Stroke—Reply

Brian H. Buck, MD, MSc1; Michael D. Hill, MD2; Derek V. Exner, MD, MPH3

doi : 10.1001/jama.2021.13490

JAMA. 2021;326(14):1439-1440

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Error in Results

doi : 10.1001/jama.2021.16131

JAMA. 2021;326(14):1440

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Editorial on Screening for Chlamydia and Gonorrhea Corrected

doi : 10.1001/jama.2021.16630

JAMA. 2021;326(14):1440

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