JAMA - Journal of the American Medical Association




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Effect of Thrombectomy With Combined Contact Aspiration and Stent Retriever vs Stent Retriever Alone on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel OcclusionThe ASTER2 Randomized Clinical Trial

Bertrand Lapergue, MD, PhD1; Raphaël Blanc, MD2; Vincent Costalat, MD, PhD3; Hubert Desal, MD, PhD4; Susanna Saleme, MD5; Laurent Spelle, MD, PhD6; Gaultier Marnat, MD7; Eimad Shotar, MD8; Francois Eugene, MD9; Mikael Mazighi, MD, PhD2; Emmanuel Houdart, MD, PhD10; Arturo Consoli, MD1,11; Georges Rodesch, MD, PhD2,11; Romain Bourcier, MD, PhD4; Serge Bracard, MD, PhD12; Alain Duhamel, PhD13; Maalek Ben Maacha, RN2; Delphine Lopez, RN1; Nicholas Renaud, RN1; Julien Labreuche, MSc13; Benjamin Gory, MD, PhD12; Michel Piotin, MD, PhD2; for the ASTER2 Trial Investigators

doi : 10.1001/jama.2021.13827

JAMA. 2021;326(12):1158-1169

Mechanical thrombectomy using a stent retriever or contact aspiration is widely used for treatment of patients with acute ischemic stroke due to anterior circulation large vessel occlusion, but the additional benefit of combining contact aspiration with stent retriever is uncertain.

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Association of Labor Epidural Analgesia With Autism Spectrum Disorder in Children

Anders Pretzmann Mikkelsen, MD1,2; Iben Katinka Greiber, MD1,2; Nikolai Madrid Scheller, MD1,3; Øjvind Lidegaard, MD, DMSc1,2

doi : 10.1001/jama.2021.12655

JAMA. 2021;326(12):1170-1177

A recent cohort study found that epidural analgesia during labor was associated with an increased risk of autism in offspring.

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Association of Epidural Analgesia During Labor and Delivery With Autism Spectrum Disorder in Offspring

Gillian E. Hanley, PhD1,2; Celeste Bickford, BSc4; Angie Ip, MD2,3; Nancy Lanphear, MD2,3; Bruce Lanphear, MD, MPH2,5; Whitney Weikum, PhD2,3; Lonnie Zwaigenbaum, MD, MSc6; Tim F. Oberlander, MD2,3,4

doi : 10.1001/jama.2021.14986

JAMA. 2021;326(12):1178-1185

Evidence from studies investigating the association of epidural analgesia use during labor and delivery with risk of autism spectrum disorder (ASD) in offspring is conflicting.

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Myocarditis and Pericarditis After Vaccination for COVID-19

George A. Diaz, MD1; Guilford T. Parsons, MD, MS2; Sara K. Gering, BS, BSN3; Audrey R. Meier, MPH4; Ian V. Hutchinson, PhD, DSc5; Ari Robicsek, MD2

doi : 10.1001/jama.2021.13443

JAMA. 2021;326(12):1210-1212

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Aspirin Use to Prevent Preeclampsia and Related Morbidity and MortalityUS Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force

doi : 10.1001/jama.2021.14781

JAMA. 2021;326(12):1186-1191

Preeclampsia is one of the most serious health problems that affect pregnant persons. It is a complication in approximately 4% of pregnancies in the US and contributes to both maternal and infant morbidity and mortality. Preeclampsia also accounts for 6% of preterm births and 19% of medically indicated preterm births in the US. There are racial and ethnic disparities in the prevalence of and mortality from preeclampsia. Non-Hispanic Black women are at greater risk for developing preeclampsia than other women and experience higher rates of maternal and infant morbidity and perinatal mortality.

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Aspirin Use to Prevent Preeclampsia and Related Morbidity and MortalityUpdated Evidence Report and Systematic Review for the US Preventive Services Task Force

Jillian T. Henderson, PhD, MPH1; Kimberly K. Vesco, MD, MPH1; Caitlyn A. Senger, MPH1; Rachel G. Thomas, MPH1; Nadia Redmond, MSPH1

doi : 10.1001/jama.2021.8551

JAMA. 2021;326(12):1192-1206

Preeclampsia is a hypertensive disorder of pregnancy that poses serious maternal and infant health risks. Previous systematic reviews have established benefits of low-dose aspirin taken during pregnancy to prevent preeclampsia and its sequelae.

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COVID-19 in CanadaExperience and Response to Waves 2 and 3

Allan S. Detsky, MD, PhD1,2; Isaac I. Bogoch, MD, MS3,4

doi : 10.1001/jama.2021.14797

JAMA. 2021;326(12):1145-1146

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World Trade Center Health Program, 2012-2020Implications for Clinicians and Health Care Systems

Alejandro Azofeifa, DDS, MSc, MPH1; Gayatri R. Martin, MD, MPH1; John Howard, MD, JD1

doi : 10.1001/jama.2021.15739

JAMA. 2021;326(12):1147-1148

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Governing Human Germline Editing Through Patent Law

Jacob S. Sherkow, JD, MA1,2; Eli Y. Adashi, MD, MS3; I. Glenn Cohen, JD4

doi : 10.1001/jama.2021.13824

JAMA. 2021;326(12):1149-1150

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Shots in Arms

Shara L. Kronmal, MD, PhD1

doi : 10.1001/jama.2021.15671

JAMA. 2021;326(12):1151-1152

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Low-Dose Aspirin for the Prevention of Preeclampsia

Jimmy Espinoza, MD, MSc1

doi : 10.1001/jama.2021.14646

JAMA. 2021;326(12):1153-1155

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Labor Epidural Analgesia and Autism Spectrum DisorderIs There an Association?

Cynthia A. Wong, MD1; Hanna Stevens, MD, PhD2

doi : 10.1001/jama.2021.15369

JAMA. 2021;326(12):1155-1157

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Safety Culture as a Patient Safety Practice for Alarm Fatigue

Bradford D. Winters, MD, PhD1; Jennifer M. Slota, BA2; Karl Y. Bilimoria, MD, MS2

doi : 10.1001/jama.2021.8316

JAMA. 2021;326(12):1207-1208

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Why Farmworkers Need More Than New Laws for Protection From Heat-Related Illness

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.15454

JAMA. 2021;326(12):1135-1137

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Shifting Trends in West Nile and Other Arboviral Diseases

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.15826

JAMA. 2021;326(12):1140

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Salmonella Outbreak Is Linked to Restaurant Rather Than Food

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.15219

JAMA. 2021;326(12):1140

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Early Rehabilitation Leads to Better Function in Heart Failure

Anita Slomski

doi : 10.1001/jama.2021.15004

JAMA. 2021;326(12):1139

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Pain Management Video Reduces Opioid Use After Cesarean Delivery

Anita Slomski

doi : 10.1001/jama.2021.15934

JAMA. 2021;326(12):1139

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Remote Monitoring Reduced Symptoms Among Patients With Cancer

Anita Slomski

doi : 10.1001/jama.2021.15935

JAMA. 2021;326(12):1139

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Closed-Loop Insulin Delivery for Outpatients With Type 2 Diabetes

Anita Slomski

doi : 10.1001/jama.2021.15936

JAMA. 2021;326(12):1139

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COVID-19 Vaccine Nasal Spray

Rita Rubin, MA

doi : 10.1001/jama.2021.14996

JAMA. 2021;326(12):1138

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New Grants for Suicide Prevention

Rita Rubin, MA

doi : 10.1001/jama.2021.15923

JAMA. 2021;326(12):1138

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Tracking COVID-19 Supply Shortages

Rita Rubin, MA

doi : 10.1001/jama.2021.15924

JAMA. 2021;326(12):1138

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Time of Death

Jamie C. Riches, DO1

doi : 10.1001/jama.2021.11525

JAMA. 2021;326(12):1217

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A Comparison of Greek and Modern Scientific Methods

doi : 10.1001/jama.2020.18146

JAMA. 2021;326(12):1218

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Use of Aspirin During Pregnancy to Prevent Preeclampsia

Jill Jin, MD, MPH1

doi : 10.1001/jama.2021.15900

JAMA. 2021;326(12):1222

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Association of Coronary Artery Bypass Grafting vs Percutaneous Coronary Intervention With Memory Decline in Older Adults

Marco Zuin, MD1; Gianluca Rigatelli, MD, PhD2; Giovanni Zuliani, MD, PhD1

doi : 10.1001/jama.2021.11976

JAMA. 2021;326(12):1212-1213

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Association of Coronary Artery Bypass Grafting vs Percutaneous Coronary Intervention With Memory Decline in Older Adults—Reply

Elizabeth L. Whitlock, MD, MSc1; M. Maria Glymour, ScD, MS2

doi : 10.1001/jama.2021.11978

JAMA. 2021;326(12):1213

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Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy and Body Weight in Adults With Overweight or Obesity

Christopher K. Rayner, MBBS, PhD1; Karen L. Jones, DipAppSc, PhD1; Michael Horowitz, MBBS, PhD1

doi : 10.1001/jama.2021.13021

JAMA. 2021;326(12):1213-1214

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Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy and Body Weight in Adults With Overweight or Obesity—Reply

Ildiko Lingvay, MD, MPH, MSCS1; W. Timothy Garvey, MD2; Thomas A. Wadden, PhD3

doi : 10.1001/jama.2021.13024

JAMA. 2021;326(12):1214-1215

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