JACC: Clinical Electrophysiology




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Cardiac Resynchronization and Circulating Markers of Sarcoplasmic Reticulum Calcium Handling and Sudden Death Risk

NingJiangMDaAnyuZhouMD, PhDbHafizImranMDbGuangbinShiMD, MSbBahaaKaseerMDbVincentSiuMD, MScAntony F.ChuMDbDavid M.DonaldsonMDdMalcolm M.KirkMDbBinu B.PhilipsMDeSamuel C.DudleyJr.MD, PhDf

doi : 10.1016/j.jacep.2021.07.003

Volume 7, Issue 9, September 2021, Pages 1079-1083

Cardiac resynchronization therapy (CRT) can improve heart function and decrease arrhythmic events. We tested whether CRT altered circulating markers of calcium handling and sudden death risk. Circulating cardiac sodium channel messenger RNA (mRNA) splicing variants indicate arrhythmic risk, and a reduction in sarco/endoplasmic reticulum calcium adenosine triphosphatase 2a (SERCA2a) is thought to diminish contractility in heart failure. CRT was associated with a decreased proportion of circulating, nonfunctional sodium channels and improved SERCA2a mRNA expression. Patients without CRT did not have improvement in the biomarkers. These changes might explain the lower arrhythmic risk and improved contractility associated with CRT.

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Any Way You Splice It, We Need Better Risk Prediction Tools for Sudden Cardiac Death?

David S.ParkMD, PhD

doi : 10.1016/j.jacep.2021.08.001

Volume 7, Issue 9, September 2021, Pages 1084-1086

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Incidence and Predictors of Sudden Cardiac Arrest in Sarcoidosis: A Nationwide Analysis

BharatNarasimhanMDaNeelPatelMDbKamHoMDaBirendraAmgaiMDbDavid R.OkadaMDcDhrubajyotiBandyopadhyayMDdChayakritKrittanawongMDeLinglingWuMDaKirtipalBhatiaMDaRushilShahMDcAshishCorreaMDaDavendraMehtaMDa

doi : 10.1016/j.jacep.2021.01.022

Volume 7, Issue 9, September 2021, Pages 1087-1095

This study sought to identify electrocardiographic (ECG) and clinical predictors of sudden cardiac arrest (SCA) in sarcoidosis.

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Masquerading Clinical Features Associated With Sudden Cardiac Arrest in Sarcoidosis?

JonathanChrispinMD

doi : 10.1016/j.jacep.2021.02.012

Volume 7, Issue 9, September 2021, Pages 1096-1098

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Hospitalization for Heart Failure and Subsequent Ventricular Tachyarrhythmias in Patients With Left Ventricular Dysfunction

ArwaYounisMDMehmet K.AktasMDDanielLeeWojciechZarebaMD, PhDScottMcNittMSBronislavaPolonskyMSValentinaKutyifaMD, PhDSpencerRoseroMDDavidHuangMDHimabinduVidulaMDIlanGoldenbergMD

doi : 10.1016/j.jacep.2021.01.021

Volume 7, Issue 9, September 2021, Pages 1099-1107

This study aimed to evaluate the risk of sustained life-threatening ventricular tachyarrhythmias (VTAs) after hospitalization for heart failure (HHF).

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Long-Term Outcomes of Near-Zero Radiation Ablation of Paroxysmal Supraventricular Tachycardia: A Comparison With Fluoroscopy-Guided Approach

MarcoBergontiMDa?AntonioDello RussoMD, PhDbc?RitaSicusoMDdValentinaRibattiMD, PhDdPaoloCompagnucciMDbcValentinaCattoPhDdAlessioGasperettiMDcMartinaZucchettiMDdSeleneCellucciBScdGiuliaVettorMD, PhDdMaria AntoniettaDessanaiMDdBenedettaMajocchiMDdMassimoMoltrasioMDdEleonoraRussoMDeGiuliaStronatiMDbcFedericoGuerraMDbcLuigiDi BiaseMD, PhDfAndreaNataleMDgClaudioTondoMD, PhDadMichelaCasellaMD, PhDbh

doi : 10.1016/j.jacep.2021.02.017

Volume 7, Issue 9, September 2021, Pages 1108-1117

This study aimed to assess the long-term outcomes of minimally fluoroscopic approach (MFA) compared with conventional fluoroscopic ablation (ConvA) in terms of recurrences of arrhythmia and long-term complications.

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The Evolution of a Gold Standard in Cardiac Electrophysiology?

John K.TriedmanMD

doi : 10.1016/j.jacep.2021.02.010

Volume 7, Issue 9, September 2021, Pages 1118-1119

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Atrial Fibrillation in Patients Hospitalized With COVID-19: Incidence, Predictors, Outcomes, and Comparison to Influenza

Daniel R.MusikantowMDa?Mohit K.TuragamMDa?SamanthaSartoriPhDaEdwardChuMDaIwanariKawamuraMDaPoojitaShivamurthyMDaMahmoudBokhariMDaConnorOatesMDaChiZhangMDaChristopherPumillMDaWaqasMalickMDaHelenHashemiMDaTaniaRuiz-MayaMDaMichael B.HadleyMDaJonathanGandhiMDaDylanSperlingMDaWilliamWhangMDbJacob S.KoruthMDb…Vivek Y.ReddyMDad

doi : 10.1016/j.jacep.2021.02.009

Volume 7, Issue 9, September 2021, Pages 1120-1130

The goal of this study is to determine the incidence, predictors, and outcomes of atrial fibrillation (AF) or atrial flutter (AFL) in patients hospitalized with coronavirus disease-2019 (COVID-19).

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Atrial Arrhythmias and the Pandemic?

Larry A.ChinitzMD

doi : 10.1016/j.jacep.2021.03.011

Volume 7, Issue 9, September 2021, Pages 1131-1133

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The Incidence and Natural Progression of New-Onset Postoperative Atrial Fibrillation

Sahar S.AbdelmoneimMD, MSEmelieRosenbergMDMarcellaMeyklerBABimalPatelMDBharathReddyMDJeanHoBAIgorKlemMDJaspalSinghBABerhaneWorkuMDRobert F.TranbaughMDTerrence J.SacchiMDJohn F.HeitnerMD

doi : 10.1016/j.jacep.2021.02.005

Volume 7, Issue 9, September 2021, Pages 1134-1144

This study aimed to characterize the natural progression and recurrence of new-onset postoperative atrial fibrillation (POAF) during an intermediate-term follow-up post cardiac surgery by using continuous event monitoring.

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Defibrillation Safety Margin Testing in Patients With Congenital Heart Disease: Results From the NCDR

Jordan M.PrutkinMD, MHSaYongfeiWangMSbcCarolina A.EscuderoMDdElizabeth A.StephensonMDeKarl E.MingesPhD, MPHcJeptha P.CurtisMDbcJonathan C.HsuMD, MASf

doi : 10.1016/j.jacep.2021.02.019

Volume 7, Issue 9, September 2021, Pages 1145-1154

This study analyzed the predictors of defibrillation safety margin (DSM) testing at the time of implantable cardioverter-defibrillator (ICD) insertion and factors associated with inadequate DSM in patients with congenital heart disease (CHD).

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Left Bundle Branch Block–Induced Cardiomyopathy: Insights From Left Bundle Branch Pacing

Shunmuga SundaramPonnusamyMDaPugazhendhiVijayaramanMDb

doi : 10.1016/j.jacep.2021.02.004

Volume 7, Issue 9, September 2021, Pages 1155-1165

The aim of the study was to report the efficacy of left bundle branch pacing (LBBP) in the management of left bundle branch block (LBBB)-induced cardiomyopathy (LIC).

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Evaluation of the Criteria to Distinguish Left Bundle Branch Pacing From Left Ventricular Septal Pacing

ShengjieWuMDab?XueyingChenMD, PhDc?SongjieWangMDabLeiXuMDabFangyiXiaoMDabZhouqingHuangMDabRujieZhengMDabLimengJiangMDabPugazhendhiVijayaramanMDdParikshit S.SharmaMDeLanSuMDabWeijianHuangMDab

doi : 10.1016/j.jacep.2021.02.018

Volume 7, Issue 9, September 2021, Pages 1166-1177

This study sought to assess the predictive value of the proposed electrocardiogram and intracardiac electrogram characteristics for confirmation of left bundle branch (LBB) capture.

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The Burden of Proof in Defining Conduction Pacing Criteria: Back to Fundamental Electrophysiology?

RoderickTungMDGaurav A.UpadhyayMD

doi : 10.1016/j.jacep.2021.06.003

Volume 7, Issue 9, September 2021, Pages 1178-1181

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Risk Factors for Repeat Infection and Mortality After Extraction of Infected Cardiovascular Implantable Electronic Devices

RyohsukeNaruiMD, PhDIkutaroNakajimaMD, PhDCalebNortonMDBenjamin B.HolmesMDZachary T.YonedaMDNeilPhillipsMDAndrewSchafferBAAlexTinianowBAAsad A.AboudMDWilliam G.StevensonMDTravis D.RichardsonMDChristopher R.EllisMDGeorge H.CrossleyIIIMDJay A.MontgomeryMD

doi : 10.1016/j.jacep.2021.01.010

Volume 7, Issue 9, September 2021, Pages 1182-1192

This study sought to investigate the factors associated with repeat infection following lead extraction procedures.

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Idiopathic Atypical Atrial Flutter Is Associated With a Distinct Atriopathy

Tharian S.CherianMDGregorySuppleMDJeffreySmietanaMDPasqualeSantangeliMD, PhDSamanNazarianMD, PhDDavidLinMDMatthew C.HymanMD, PhDKatieWalshMDFrancisMarchlinskiMDJeffreyArklesMD

doi : 10.1016/j.jacep.2021.05.004

Volume 7, Issue 9, September 2021, Pages 1193-1195

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Estimating Left Ventricular Electrical Delay From the Right Ventricular Lead Electrogram

Michael R.GoldMD, PhDKris Z.SiejkoMSYinghongYuMSAngeloAuricchioMD, PhD

doi : 10.1016/j.jacep.2021.07.004

Volume 7, Issue 9, September 2021, Pages 1195-1196

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COVID-19 and AF: What About the Long Game?

Maria E.VadakkenEmilie P.Belley-CoteMD, PhDWilliam F.McIntyreMD, PhD

doi : 10.1016/j.jacep.2021.05.018

Volume 7, Issue 9, September 2021, Pages 1196-1197

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Ebstein’s Anomaly: Review of Arrhythmia Types and Morphogenesis of the Anomaly

Beixin JulieHeMD, PhDabAlexander F.MerrimanMScIvanCakulevMDdBruce S.StamblerMDeDeepakSrivastavaMDcfgMelvin M.ScheinmanMDh

doi : 10.1016/j.jacep.2021.05.008

Volume 7, Issue 9, September 2021, Pages 1198-1206

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Pericardiophrenic–Pulmonary Vein Communication: A Rare Connection

MartínQuintas-GuzmánMDIgnacioMosquera-PérezMD, PhDJorgeRodríguez-GarridoMDEnriqueRicoy-MartínezMD, PhDLuisaPérez-ÁlvarezMD, PhD

doi : 10.1016/j.jacep.2021.04.010

Volume 7, Issue 9, September 2021, Pages 1207-1208

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A Heartwarming Story

ChristopherCheungMD, MPHMelvinScheinmanMDHenryHsiaMD

doi : 10.1016/j.jacep.2021.06.007

Volume 7, Issue 9, September 2021, Pages 1209-1210

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