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Risk of anticholinergic burden in adults with intellectual disabilities: a Scottish retrospective cohort study of n = 17 220
L. M. Ward,B. Stanley,N. Greenlaw,S.-A. Cooper,C. Pacitti,A. Henderson,J. Gibson,D. Kinnear,
doi : 10.1111/jir.12861
Volume 65, Issue 9 p. 813-830
Several drugs have anticholinergic side effects that are associated with adverse health outcomes. Anticholinergic burden studies in adults with intellectual disabilities (ID) have focused exclusively on older adults. This study investigates anticholinergic burden and its associations in adults with ID of all ages (17–94 years).
Cognitive assessment using the Rapid Assessment for Developmental Disabilities, Second Edition (RADD-2)
C. L. Hom,D. Walsh,G. Fernandez,A. Tournay,P. Touchette,I. T. Lott,
doi : 10.1111/jir.12863
Volume 65, Issue 9 p. 831-848
Individuals with developmental disabilities (DD) often have severe impairments and maladaptive behaviours that make it difficult to reliably assess their cognitive abilities. Given these challenges, the Rapid Assessment of Developmental Disabilities, Second Edition (RADD-2), was designed to measure general cognitive ability in this population. The purpose of this study is to demonstrate the battery's psychometric properties when used with individuals with DD who have challenging behavioural and psychiatric conditions and for those who have limited verbal skills.
Marrying into it: Siblings-in-law in the social support networks of adults with intellectual and developmental disabilities
J. L. Bumble,K. A. Sanderson,K. E. Zemke,R. M. Hodapp,
doi : 10.1111/jir.12864
Volume 65, Issue 9 p. 849-862
Although attention has been devoted to social supports provided by parents and siblings of adults with intellectual and developmental disabilities (IDD), much less is known about supports provided by the spouses of these siblings—the so-called siblings-in-law. This study examined the role of the sibling-in-law in the social support networks of their brother/sister-in-law with IDD and factors associated with providing greater amounts of tangible, informational and emotional support.
A 343 Italian cohort of patients analysed with array-comparative genomic hybridization: unsolved problems and genetic counselling difficulties
C. Palka Bayard de Volo,M. Alfonsi,E. Morizio,P. Guaciali-Franchi,A. Mohn,F. Chiarelli,
doi : 10.1111/jir.12867
Volume 65, Issue 9 p. 863-869
The recent introduction of microarrays for genetic analyses has allowed higher etiological diagnostic rates in patient with intellectual disability (ID), autism spectrum disorders (ASD), epilepsy and multiple congenital anomalies (MCA), because of its resolution. This approach still results of high complexity and some limitations have been reported. In fact, it discloses several variants of unknown significance (VOUS) or incidental findings. In all cases, a massive amount of data is generated, because of this, the analysis and the interpretation is very difficult and often without a definitive conclusion.
Social involvement, socio-economic status and subjective well-being of parents of offspring with intellectual and developmental disabilities
A. Gur,A. Rimmerman,
doi : 10.1111/jir.12841
Volume 65, Issue 9 p. 870-877
The study explores whether households' socio-economic status and social involvement can moderate the association between stress and subjective well-being among parents of offspring with intellectual and developmental disabilities (IDD).
