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Application of an evidence-based, out-patient treatment strategy for COVID-19: Multidisciplinary medical practice principles to prevent severe disease
Elliot M. Frohman,Nicole R. Villemarette-Pittman,Adriana Rodriguez,Matthew S. Parsons,Emily Heckmann Konkle,Teresa C. Frohman
doi : 10.1016/j.jns.2021.117463
VOLUME 426, 117463, JULY 15, 2021
The COVID-19 pandemic has devastated individuals, families, and institutions throughout the world. Despite the breakneck speed of vaccine development, the human population remains at risk of further devastation. The decision to not become vaccinated, the protracted rollout of available vaccine, vaccine failure, mutational forms of the SARS virus, which may exhibit mounting resistance to our molecular strike at only one form of the viral family, and the rapid ability of the virus(es) to hitch a ride on our global transportation systems, means that we are will likely continue to confront an invisible, yet devastating foe. The enemy targets one of our human physiology’s most important and vulnerable life-preserving body tissues, our broncho-alveolar gas exchange apparatus.
White matter hyperintensities in patients with Parkinson's disease: A systematic review and meta-analysis
Asif Butt,Joseph Kamtchum-Tatuene,Khurshid Khan,Janis M. Miyasaki,Eric E. Smith,Richard Camicioli
doi : 10.1016/j.jns.2021.117481
VOLUME 426, 117481, JULY 15, 2021
Mechanisms driving neurodegeneration in Parkinson's disease (PD) are unclear and neurovascular dysfunction may be a contributing factor. White matter hyperintensities (WMH) are commonly found on brain MRI in patients with PD. It is controversial if they are more prevalent or more severe in PD compared with controls. This systematic review aims to answer this question.
Wernicke-Korsakoff syndrome despite no alcohol abuse: A summary of systematic reports
Erik Oudman,Jan W. Wijnia,Misha J. Oey,Mirjam van Dam,Albert Postma
doi : 10.1016/j.jns.2021.117482
VOLUME 426, 117482, JULY 15, 2021
Wernicke-Korsakoff syndrome (WKS) is a neurological disorder typically found in alcohol use disorder. The fact that it also occurs in nonalcoholic patients is less well known and often ignored. For the first time, this review offers a systematic investigation of the frequency and associated features of nonalcoholic WKS in the published literature.
Asymptomatic acute ischemic lesions in intracerebral hemorrhage: Its frequency, MRI features, and risk factors
Eiji Kitamura,Takahiro Iizuka,Noritaka Mamorita,Tsugio Akutsu,Naomi Kanazawa,Kazutoshi Nishiyama
doi : 10.1016/j.jns.2021.117472
VOLUME 426, 117472, JULY 15, 2021
Asymptomatic acute ischemic lesions (AIL) may be coincidentally found on brain magnetic resonance imaging (MRI) obtained during the acute phase of intracerebral hemorrhage, but its clinical significance has yet to be determined. The objective of this study is to determine the frequency of asymptomatic AIL, its characteristic features of brain MRI and risk factors in patients with acute intracerebral hemorrhage.
Quality of life in multiple sclerosis is dominated by fatigue, disability and self-efficacy
Carolyn A. Young,Roger Mills,David Rog,Helen L. Ford,John Woolmore,Alan Tennant
doi : 10.1016/j.jns.2021.117437
VOLUME 426, 117437, JULY 15, 2021
Quality of life in multiple sclerosis (MS) reflects complex relationships between symptoms (fatigue, spasticity pain, and bladder or vision dysfunction), disability, health perceptions, and self-efficacy.
Relationship between 123I-FP-CIT-SPECT and motor severity in drug-naive patients with Parkinson's disease
Hiroo Terashi,Takeshi Taguchi,Yuki Ueta,Hiroshi Mitoma,Hitoshi Aizawa
doi : 10.1016/j.jns.2021.117476
VOLUME 426, 117476, JULY 15, 2021
Although functional imaging is useful for the diagnosis and pathophysiological evaluation of Parkinson's disease (PD), little is known about the relationship between functional imaging findings and PD clinical features. The objective of this study was to determine the relationship between 123I-FP-CIT-SPECT findings and motor symptoms, in particular gait disturbance.
Blood pressure control measured as “time in range” during initial 24 h for inpatients with spontaneous nontraumatic intracerebral haemorrhage
Arshee Khan,Niaz Shaikh,Yasir Alvi,Priyank Gupta,Rommana Mehdi,Aisha Siddiqui
doi : 10.1016/j.jns.2021.117480
VOLUME 426, 117480, JULY 15, 2021
Blood pressure (BP) control is an integral part in the management of spontaneous nontraumatic intracerebral haemorrhage. The aim of this study is to propose a novel concept of blood pressure control measured as ‘Time in Range’(TiR) and assess its relationship to neurological deterioration.
Comparison of baroreflex sensitivity indices with standard tests of autonomic nervous system function
Ivan Moštak,Nika Višnji?,Anamari Junakovi?,Magdalena Krbot Skori?,Mario Habek
doi : 10.1016/j.jns.2021.117473
VOLUME 426, 117473, JULY 15, 2021
In order to further evaluate clinical usefulness of ?- and ?-adrenergic components of the baroreflex sensitivity (BRS) index, the aim of this study was to compare them to standardized measures of the autonomic dysfunction.
Comparison of automated infarct core volume measures between non-contrast computed tomography and perfusion imaging in acute stroke code patients evaluated for potential endovascular treatment
Olli P. Suomalainen,Ahmed Abou Elseoud,Nicolas Martinez-Majander,Marjaana Tiainen,Nina Forss,Sami Curtze
doi : 10.1016/j.jns.2021.117483
VOLUME 426, 117483, JULY 15, 2021
Patients with small core infarction and salvageable penumbra are likely to benefit from endovascular treatment (EVT). As computed tomography perfusion imaging (CTP) is not always available 24/7 for patient selection, many patients are transferred to stroke centers for CTP. We compared automatically measured infarct core volume (NCCTcore) from the non-contrast computed tomography (NCCT) with ischemic core volume (CTPcore) from CTP and the outcome of EVT to clarify if NCCTcore measurement alone is sufficient to identify patients that benefit from transfer to stroke centers for EVT.
A prospective study of long-term outcomes among hospitalized COVID-19 patients with and without neurological complications
Jennifer A. Frontera,Dixon Yang,Ariane Lewis,Chris Morrison,Shadi Yaghi,Steven Galetta
doi : 10.1016/j.jns.2021.117486
VOLUME 426, 117486, JULY 15, 2021
Little is known regarding long-term outcomes of patients hospitalized with COVID-19.
Objective vowel sound characteristics and their relationship with motor dysfunction in Asian Parkinson's disease patients
Pawichaya Suphinnapong,Onanong Phokaewvarangkul,Nuttakorn Thubthong,Patnarin Mahattanasakul,Preeya Lorwattanapongsa,Roongroj Bhidayasiri
doi : 10.1016/j.jns.2021.117487
VOLUME 426, 117487, JULY 15, 2021
Speech impairments are very common in patients with Parkinson's disease (PD). However, knowledge of their objective characteristics and relationship to other motor symptoms amongst Asian PD patients is limited.
Diversity in neurology leadership: Nuances and nudges
Larry Charleston IV,Bruce Ovbiagele
doi : 10.1016/j.jns.2021.117475
VOLUME 426, 117475, JULY 15, 2021
Underrepresented in medicine (UIM) academic physicians are poorly represented among medical school faculty when compared with their proportion in the US population, receive NIH research awards less frequently, are promoted less often, indicate lower career satisfaction, and report higher social isolation, than faculty who are not under-represented.
Impact of SARS-CoV-2 infection on acute intracerebral haemorrhage in northern Italy
Davide Sangalli,Filippo Martinelli-Boneschi,Maurizio Versino,Antonio Colombo,Andrea Salmaggion behalf of the SNO-COVID-19 group
doi : 10.1016/j.jns.2021.117479
VOLUME 426, 117479, JULY 15, 2021
Growing evidence has been published as to the impact of SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) on cerebrovascular events over the last few months, with considerable attention paid to ischemic strokes. Conversely, little is known about the clinical course of intracerebral haemorrhage (ICH) and simultaneous SARS-CoV-2 infection.
COVID-19 and fatigue: Where do we go from here? Response to Ortelli et al.
Isabella Conti,Benjamin Cross,Alasdair G. Rooney,Timothy R. Nicholson
doi : 10.1016/j.jns.2021.117470
VOLUME 426, 117470, JULY 15, 2021
Potential of videoconferencing to augment clinical teaching of neurology in Ghana
Fred Stephen Sarfo,Bruce Ovbiagele
doi : 10.1016/j.jns.2021.117471
VOLUME 426, 117471, JULY 15, 2021
Micturition induced primary thunderclap headache in an 11-year-old with response to nimodipine
Katherine M. Wojcicki,Rachel L. Evans,Benjamin Zwain,Stephen Deputy
doi : 10.1016/j.jns.2021.117474
VOLUME 426, 117474, JULY 15, 2021
Ischemic stroke associated with aneurysmal lenticulostriate vasculopathy and symmetric reversible basal ganglia lesions in COVID-19
Jamie Strause,Kofi-Buaku Atsina,Darren Bialo,Jonathan Orwitz,Ronald L. Wolf,Brett Cucchiara
doi : 10.1016/j.jns.2021.117484
VOLUME 426, 117484, JULY 15, 2021
The clinical spectrum of multisystem proteinopathy: Data from a neurodegenerative cohort
Veria Vacchiano,Nicola Mometto,Anna Bartoletti-Stella,Piero Parchi,Rocco Liguori,Sabina Capellari
doi : 10.1016/j.jns.2021.117478
VOLUME 426, 117478, JULY 15, 2021
An uncommon disease included commonly in the differential diagnosis of neurological diseases: Neuro-Behçet's syndrome
Ugur Uygunoglu,Aksel Siva
doi : 10.1016/j.jns.2021.117436
VOLUME 426, 117436, JULY 15, 2021
Behçet’s Syndrome (BS) may present with different neurological problems, related either directly (primary) or indirectly (secondary) to BS. Primary neurological involvement is named as neuro-Behcet’s syndrome (NBS), and its two major subtypes that are classified mainly on the clinical and MRI findings are (1) Parenchymal-NBS (p-NBS) and (2) Extra parenchymal neuro-vascular involvement mostly seen as cerebral dural venous sinus thrombosis (CVST). The less commonly seen forms of NBS are cognitive and behavioral syndromes and peripheral nervous system involvement.
