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Perspective: Putting the youngest among us into the nutrition “call for action” for food fortification strategies
Stanley Zlotkin, Kathryn G Dewey
doi : 10.1093/ajcn/nqab207
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1257–1260
Adequate iron intake is essential for optimal child development, but iron deficiency and anemia among infants and young children are widespread in low- and middle-income countries. Large-scale food fortification strategies hold great promise for reducing micronutrient deficiencies; however, for children <2 y of age, the impact of such strategies is limited because their intake of staple foods is relatively low and fortification levels are targeted at the adult population. Iron supplementation, iron fortification of foods targeted to infants, and point-of-use fortification with iron-containing products such as multiple micronutrient powders (MNPs) and small-quantity lipid-based nutrient supplements are evidence-based approaches recommended to reduce anemia among infants and young children when used in the right context. Since 2003, the WHO, with support from UNICEF, has recommended the use of MNPs to control iron deficiency. However, the percentage of children with anemia has changed very little over the past 10 y. Five years ago the UN declared a decade of action on nutrition, including World Health Assembly (WHA) targets for maternal, infant, and young child nutrition, yet the WHA set no anemia targets for children. In July 2020 the leaders of 4 UN agencies issued a call for action to protect children's right to nutrition in the face of the COVID-19 pandemic and beyond. Given persistently high rates of anemia among young children, the negative developmental impact, the challenge of meeting iron needs from typical complementary food diets, and the availability of successful evidence-based fortification strategies for this age group, we encourage planners, speakers, and donors at this year's UN Food Systems Summit and the Tokyo Nutrition for Growth Summit to 1) call for the WHA to set anemia targets for infants and young children and 2) promote investment in evidence-based interventions to improve the iron status of young children.
Perspective: When the cure might become the malady: the layering of multiple interventions with mandatory micronutrient fortification of foods in India
Anura V Kurpad, Santu Ghosh, Tinku Thomas, Sulagna Bandyopadhyay, Ravinder Goswami, Arun Gupta, Piyush Gupta, Anjaly T John, Umesh Kapil, Bharati Kulkarni, Rebecca Kuriyan, Jagmeet Madan, Sanchit Makkar, Krishnapillai M Nair, Raghu Pullakhandam, G Bhanuprakash Reddy, Dheeraj Shah, Harshpal S Sachdev
doi : 10.1093/ajcn/nqab245
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1261–1266
When public health programs with single nutrients are perceived to have a poor impact on the target health outcome, the policy response can be to supply more, by layering additional mandatory programs upon the extant programs. However, we argue for extreme caution, because nutrients (like medicines) are beneficial in the right dose, but potentially harmful when ingested in excess. Unnecessary motivations for the reactionary layering of multiple intervention programs emerge from incorrect measurements of the risk of nutrient inadequacy in the population, or incorrect biomarker cutoffs to evaluate the extent of nutrient deficiencies. The financial and social costs of additional layered programs are not trivial when traded off with other vital programs in a resource-poor economy, and when public health ethical dilemmas of autonomy, equity, and stigma are not addressed. An example of this conundrum in India is the perception of stagnancy in the response of the prevalence of anemia to the ongoing pharmacological iron supplementation program. The reaction has been a policy proposal to further increase iron intake through mandatory iron fortification of the rice provided in supplementary feeding programs like the Integrated Child Development Services and the School Mid-Day Meal. This is in addition to the ongoing pharmacological iron supplementation as well as other voluntary iron fortifications, such as those of salt and manufactured food products. However, before supplying more, it is vital to consider why the existing program is apparently not working, along with consideration of the potential for excess intake and related harms. This is relevant globally, particularly for countries contemplating multiple interventions to address micronutrient deficiencies. Supplying more by layering multiple nutrient interventions, instead of doing it right, without thoughtful considerations of social, biological, and ethics frameworks could be counterproductive. The cure, then, might well become the malady.
Call for emergency action to limit global temperature increases, restore biodiversity, and protect health: Wealthy nations must do much more, much faster*
Laurie Laybourn-Langton, Richard Smith
doi : 10.1093/ajcn/nqab281
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1267–1269
Does sleep restriction increase eating in the absence of hunger? Maybe!
Jean-Philippe Chaput
doi : 10.1093/ajcn/nqab214
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1270–1271
Strengthening research investigating maternal nutrition and children's neurodevelopment: How can we do it better? Where do we go from here?
Gillian England-Mason, Deborah Dewey
doi : 10.1093/ajcn/nqab256
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1272–1274
Increases in adiposity among children and adolescents over time: Moving beyond BMI
Amanda E Staiano, Peter T Katzmarzyk
doi : 10.1093/ajcn/nqab265
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1275–1276
The conundrum of delivering nutrition benefits, mitigating risks, and avoiding inertia
Lynnette M Neufeld, Mduduzi N N Mbuya
doi : 10.1093/ajcn/nqab272
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1277–1279
A guide for authors and readers of the American Society for Nutrition Journals on the proper use of P values and strategies that promote transparency and improve research reproducibility
John D Sorkin, Mark Manary, Paul A M Smeets, Amanda J MacFarlane, Arne Astrup, Ronald L Prigeon, Beth B Hogans, Jack Odle, Teresa A Davis, Katherine L Tucker, Christopher P Duggan, Deirdre K Tobias
doi : 10.1093/ajcn/nqab223
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1280–1285
Two questions regarding the scientific literature have become grist for public discussion: 1) what place should P values have in reporting the results of studies? 2) How should the perceived difficulty in replicating the results reported in published studies be addressed? We consider these questions to be 2 sides of the same coin; failing to address them can lead to an incomplete or incorrect message being sent to the reader. If P values (which are derived from the estimate of the effect size and a measure of the precision of the estimate of the effect) are used improperly, for example reporting only significant findings, or reporting P values without account for multiple comparisons, or failing to indicate the number of tests performed, the scientific record can be biased. Moreover, if there is a lack of transparency in the conduct of a study and reporting of study results, it will not be possible to repeat a study in a manner that allows inferences from the original study to be reproduced or to design and conduct a different experiment whose aim is to confirm the original study's findings. The goal of this article is to discuss how P values can be used in a manner that is consistent with the scientific method, and to increase transparency and reproducibility in the conduct and analysis of nutrition research.
Associations of atrophic gastritis and proton-pump inhibitor drug use with vitamin B-12 status, and the impact of fortified foods, in older adults
Kirsty M Porter, Leane Hoey, Catherine F Hughes, Mary Ward, Michelle Clements, Jj Strain, Conal Cunningham, Miriam C Casey, Fergal Tracey, Maurice O'Kane, Kristina Pentieva, Liadhan McAnena, Kevin McCarroll, Eamon Laird, Anne M Molloy, Helene McNulty
doi : 10.1093/ajcn/nqab193
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1286–1294
Atrophic gastritis (AG) and use of proton pump inhibitors (PPIs) result in gastric acid suppression that can impair the absorption of vitamin B-12 from foods. The crystalline vitamin B-12 form, found in fortified foods, does not require gastric acid for its absorption and could thus be beneficial for older adults with hypochlorhydria, but evidence is lacking.
Effect of 2-year caloric restriction on organ and tissue size in nonobese 21- to 50-year-old adults in a randomized clinical trial: the CALERIE study
Wei Shen, Jun Chen, Jane Zhou, Corby K Martin, Eric Ravussin, Leanne M Redman
doi : 10.1093/ajcn/nqab205
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1295–1303
Sustained calorie restriction (CR) promises to extend the lifespan. The effect of CR on changes in body mass across tissues and organs is unclear.
An emerging role of Prevotella histicola on estrogen deficiency–induced bone loss through the gut microbiota–bone axis in postmenopausal women and in ovariectomized mice
Zhongxiang Wang, Kai Chen, Congcong Wu, Junhao Chen, Hao Pan, Yangbo Liu, Peng Wu, Jiandong Yuan, Furong Huang, Junzhe Lang, Juanjuan Du, Jiake Xu, Keke Jin, Lei Chen
doi : 10.1093/ajcn/nqab194
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1304–1313
The gut microbiota (GM)–bone axis has emerged as a crucial mediator of bone homeostasis. Estrogen deficiency–induced bone loss is closely associated with an altered GM. However, the underlying mechanisms remain unclear.
A prospective study of dietary flavonoid intake and risk of glioma in US men and women
Alaina M Bever, Aedin Cassidy, Eric B Rimm, Meir J Stampfer, David J Cote
doi : 10.1093/ajcn/nqab178
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1314–1327
Flavonoids are a diverse group of plant constituents with demonstrated neuroprotective and anti-tumor effects. Flavonoid intake may decrease the risk of glioma, but the possibility of an association has not yet been investigated in humans.
Wheat bran with reduced particle size increases serum SCFAs in obese subjects without improving health parameters compared with a maltodextrin placebo
Lise Deroover, Jorge F Vázquez-Castellanos, Greet Vandermeulen, Anja Luypaerts, Jeroen Raes, Christophe M Courtin, Kristin Verbeke
doi : 10.1093/ajcn/nqab196
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1328–1341
Wheat bran (WB) has been associated with improved gastrointestinal health and a reduced risk of metabolic disorders. Reducing the particle size of WB might increase its fermentability and facilitate cross-feeding between the gut bacteria and in this way produce health effects.
Plasma TMAO increase after healthy diets: results from 2 randomized controlled trials with dietary fish, polyphenols, and whole-grain cereals
Giuseppina Costabile, Claudia Vetrani, Lutgarda Bozzetto, Rosalba Giacco, Letizia Bresciani, Daniele Del Rio, Marilena Vitale, Giuseppe Della Pepa, Furio Brighenti, Gabriele Riccardi, Angela A Rivellese, Giovanni Annuzzi
doi : 10.1093/ajcn/nqab188
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1342–1350
Plasma trimethylamine N-oxide (TMAO) has drawn much attention as a marker of several chronic diseases. Data on the relation between diet and TMAO are discordant and few human intervention studies have assessed causality for this association.
Plasma choline and betaine and risks of cardiovascular events and recurrent stroke after ischemic stroke
Chongke Zhong, Mengyuan Miao, Bizhong Che, Jigang Du, Aili Wang, Hao Peng, Xiaoqing Bu, Jintao Zhang, Zhong Ju, Tan Xu, Jiang He, Yonghong Zhang
doi : 10.1093/ajcn/nqab199
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1351–1359
Choline and betaine have been suggested to play a pivotal role in neurotransmitter synthesis, cell membrane integrity, and methyl-group metabolism, exerting neuroprotective effects in patients with various neurological disorders. However, population-based evidence on choline and betaine with subsequent cardiovascular events after stroke is rare.
Association between plasma S-adenosylmethionine and risk of mortality in patients with coronary artery disease: A cohort study
Si Liu, Ruyi Liao, Xin Dai, Honghui Guo, Dongliang Wang, Min Xia, Wenhua Ling, Yunjun Xiao
doi : 10.1093/ajcn/nqab210
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1360–1370
S-adenosylmethionine (SAM) as methyl donors participates in methylation and is converted into S-adenosylhomocysteine (SAH), which is a precursor of homocysteine. Increased plasma SAH and homocysteine are associated with increased risk of cardiovascular disease. However, the relation of plasma SAM with cardiovascular risk is still unclear.
Effects of exercise and/or ?-hydroxy-?-methylbutyrate supplementation on muscle mass, muscle strength, and physical performance in older women with low muscle mass: a randomized, double-blind, placebo-controlled trial
Yosuke Osuka, Narumi Kojima, Hiroyuki Sasai, Kyohsuke Wakaba, Daiji Miyauchi, Kiyoji Tanaka, Hunkyung Kim
doi : 10.1093/ajcn/nqab176
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1371–1385
The interaction between exercise and nutritional supplementation is unclear among older adults at risk of sarcopenia.
Are metabolic adaptations to weight changes an artefact?
Manfred J Müller, Steven B Heymsfield, Anja Bosy-Westphal
doi : 10.1093/ajcn/nqab184
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1386–1395
Adaptive thermogenesis (AT) is currently defined as the fat-free mass (FFM)–independent change in resting energy expenditure (REE) in response to caloric restriction (CR) or overfeeding (OF). So far, the impact of changes in the anatomical and molecular composition of FFM on AT has not been addressed.
Reduced adaptive thermogenesis during acute protein-imbalanced overfeeding is a metabolic hallmark of the human thrifty phenotype
Tim Hollstein, Alessio Basolo, Takafumi Ando, Jonathan Krakoff, Paolo Piaggi
doi : 10.1093/ajcn/nqab209
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1396–1407
The human thrifty phenotype is characterized by a greater decrease in 24-h energy expenditure (24EE) during fasting due to relatively higher eucaloric 24EE in sedentary conditions, both of which are indicative of greater propensity to weight gain. Thriftiness is also associated with a smaller increase in 24EE (i.e., reduced adaptive thermogenesis) during overfeeding.
Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies
Sachelly Julián-Serrano, Fangcheng Yuan, William Wheeler, Beben Benyamin, Mitchell J Machiela, Alan A Arslan, Laura E Beane-Freeman, Paige M Bracci, Eric J Duell, Mengmeng Du, Steven Gallinger, Graham G Giles, Phyllis J Goodman, Charles Kooperberg, Loic Le Marchand, Rachel E Neale, Xiao-Ou Shu, Stephen K Van Den Eeden, Kala Visvanathan, Wei Zheng, Demetrius Albanes, Gabriella Andreotti, Eva Ardanaz, Ana Babic, Sonja I Berndt, Lauren K Brais, Paul Brennan, Bas Bueno-de-Mesquita, Julie E Buring, Stephen J Chanock, Erica J Childs, Charles C Chung, Eleonora Fabiánová, Lenka Foretová, Charles S Fuchs, J Michael Gaziano, Manuel Gentiluomo, Edward L Giovannucci, Michael G Goggins, Thilo Hackert, Patricia Hartge, Manal M Hassan, Ivana Holcátová, Elizabeth A Holly, Rayjean I Hung, Vladimir Janout, Robert C Kurtz, I-Min Lee, Núria Malats, David McKean, Roger L Milne, Christina C Newton, Ann L Oberg, Sandra Perdomo, Ulrike Peters, Miquel Porta, Nathaniel Rothman, Matthias B Schulze, Howard D Sesso, Debra T Silverman, Ian M Thompson, Jean Wactawski-Wende, Elisabete Weiderpass, Nicolas Wenstzensen, Emily White, Lynne R Wilkens, Herbert Yu, Anne Zeleniuch-Jacquotte, Jun Zhong, Peter Kraft, Dounghui Li, Peter T Campbell, Gloria M Petersen, Brian M Wolpin, Harvey A Risch, Laufey T Amundadottir, Alison P Klein, Kai Yu, Rachael Z Stolzenberg-Solomon
doi : 10.1093/ajcn/nqab217
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1408–1417
Epidemiological studies have suggested positive associations for iron and red meat intake with risk of pancreatic ductal adenocarcinoma (PDAC). Inherited pathogenic variants in genes involved in the hepcidin-regulating iron metabolism pathway are known to cause iron overload and hemochromatosis.
Maternal pregnancy diet, postnatal home environment and executive function and behavior in 3- to 4-y-olds
Neda Mortaji, John E Krzeczkowski, Khrista Boylan, Linda Booij, Maude Perreault, Ryan J Van Lieshout
doi : 10.1093/ajcn/nqab202
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1418–1427
Optimal maternal nutrition during pregnancy has been linked to better cognitive and behavioral development in children. However, its influence on the effects of suboptimal postnatal exposures like reduced stimulation and support in the home is not known.
Eating in the absence of hunger in children with mild sleep loss: a randomized crossover trial with learning effects
Silke Morrison, Barbara C Galland, Jillian J Haszard, Rosie Jackson, Deborah R McIntosh, Dean W Beebe, Dawn E Elder, Aimee L Ward, Kim Meredith-Jones, Rachael W Taylor
doi : 10.1093/ajcn/nqab203
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1428–1437
While insufficient sleep duration has emerged as a strong, independent risk factor for obesity, the mechanisms remain unclear. One possibility is greater “eating in the absence of hunger” (EAH) or energy intake beyond the point of satiety, when tired.
Maternal plasma choline and betaine in late pregnancy and child growth up to age 8 years in the KOALA Birth Cohort Study
Carolina Moltó-Puigmartí, Rima Obeid, Monique Mommers, Simone Jpm Eussen, Carel Thijs
doi : 10.1093/ajcn/nqab177
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1438–1446
Sufficient choline and betaine during pregnancy are needed for fetal growth and development.
Using an erythrocyte fatty acid fingerprint to predict risk of all-cause mortality: the Framingham Offspring Cohort
Michael I McBurney, Nathan L Tintle, Ramachandran S Vasan, Aleix Sala-Vila, William S Harris
doi : 10.1093/ajcn/nqab195
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1447–1454
RBC long-chain omega-3 (n–3) fatty acid (FA) percentages (of total fatty acids) are associated with lower risk for total mortality, but it is unknown if a suite of FAs could improve risk prediction.
Effect of carbohydrate-restricted dietary interventions on LDL particle size and number in adults in the context of weight loss or weight maintenance: a systematic review and meta-analysis
Kaja Falkenhain, Lauren A Roach, Sara McCreary, Eric McArthur, Ethan J Weiss, Monique E Francois, Jonathan P Little
doi : 10.1093/ajcn/nqab212
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1455–1466
LDL particle size and number (LDL-P) are emerging lipid risk factors. Nonsystematic reviews have suggested that diets lower in carbohydrates and higher in fats may result in increased LDL particle size when compared with higher-carbohydrate diets.
Abdominal and gluteofemoral fat depots show opposing associations with postprandial lipemia
Malene R Christiansen, Mario G Ureña, Dmitrii Borisevich, Niels Grarup, J Alfredo Martínez, Jean-Michel Oppert, Thorkild Ia Sørensen, Torben Hansen, Ellen E Blaak, Tuomas O Kilpeläinen
doi : 10.1093/ajcn/nqab219
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1467–1475
High postprandial lipemia is associated with increased risk of cardiovascular disease, independently of fasting lipid concentrations. Abdominal and gluteofemoral fat depots handle lipoproteins differently, which could affect postprandial lipemia and contribute to the relation between abdominal fat distribution and cardiovascular disease risk.
Time trends in consumption of sugar-sweetened beverages and related socioeconomic differences among adolescents in Eastern Europe: signs of a nutrition transition?
Angeline Chatelan, Manon Rouche, Anna Dzielska, Thérésa Lebacq, Anne-Siri Fismen, Colette Kelly, Apolinaras Zaborskis, Jaroslava Kopcakova, Anna Tsareva, Michal Kalman, Katia Castetbon
doi : 10.1093/ajcn/nqab175
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1476–1485
High intake of sugar-sweetened beverages (SSBs) contributes to detrimental cardio-metabolic indicators in youth. Monitoring of SSB consumption is lacking in Eastern Europe.
Association of macronutrients and dietary patterns with risk of systemic lupus erythematosus in the Black Women's Health Study
Nelsy Castro-Webb, Yvette C Cozier, Medha Barbhaiya, Edward A Ruiz-Narváez, Shanshan Li, Karen H Costenbader, Lynn Rosenberg
doi : 10.1093/ajcn/nqab224
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1486–1494
Systemic lupus erythematosus (SLE) affects African-American (AA) women disproportionately. The few prospective studies assessing dietary intake in relation to risk of SLE have been conducted in predominantly white populations and have been null.
Changes in adiposity among children and adolescents in the United States, 1999–2006 to 2011–2018
Bryan Stierman, Cynthia L Ogden, Jack A Yanovski, Crescent B Martin, Neda Sarafrazi, Craig M Hales
doi : 10.1093/ajcn/nqab237
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1495–1504
Data from the NHANES indicate that BMI has increased in some subgroups of children and adolescents in the United States over the past 20 y; however, BMI is an indirect measure of body fatness.
Meat intake and risk of mortality and graft failure in kidney transplant recipients
M Yusof Said, Angelica Rodriguez-Niño, Adrian Post, Joelle C Schutten, Lyanne M Kieneker, Antonio W Gomes-Neto, Marco van Londen, Maryse Cj Osté, Karin J Borgonjen-van den Berg, Ilja M Nolte, Else van den Berg, Pim de Blaauw, Jennifer van der Krogt, M Rebecca Heiner-Fokkema, Gerjan Navis, Benito A Yard, Stephan Jl Bakker
doi : 10.1093/ajcn/nqab185
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1505–1517
It is unknown whether meat intake is beneficial for long-term patient and graft survival in kidney transplant recipients (KTR).
Higher fasting plasma FGF21 concentration is associated with lower ad libitum soda consumption in humans
Alessio Basolo, Tim Hollstein, Mujtaba H Shah, Mary Walter, Jonathan Krakoff, Susanne B Votruba, Paolo Piaggi
doi : 10.1093/ajcn/nqab204
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1518–1522
The hepatokine fibroblast growth factor 21 (FGF21) influences eating behavior and sugar consumption in rodent models. However, whether circulating FGF21 concentration is associated with food and soda intake in humans is still unclear.
Determinants of fatty acid content and composition of human milk fed to infants born weighing <1250 g
Kathryn E Hopperton, Michael A Pitino, Raphaël Chouinard-Watkins, Sara Shama, Natasha Sammut, Nicole Bando, Brock A Williams, Kathryn Walton, Alex Kiss, Sharon L Unger, Richard P Bazinet, Deborah L O'Connor
doi : 10.1093/ajcn/nqab222
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1523–1534
Infants born at very low birth weight (VLBW) are vulnerable to deficits in fatty acids (FAs) but little is known of factors that influence the intakes or composition of their human milk feeds.
Mortality and overall and specific infection complication rates in patients who receive parenteral nutrition: systematic review and meta-analysis with trial sequential analysis
Pedro H Comerlato, Joel Stefani, Luciana V Viana
doi : 10.1093/ajcn/nqab218
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1535–1545
Parenteral nutrition (PN) is an available option for nutritional therapy and is often required in the hospital setting to overcome malnutrition.
Randomized trial of a novel lifestyle intervention compared with the Diabetes Prevention Program for weight loss in adult dependents of military service members
Sai Krupa Das, Asma S Bukhari, Amy G Taetzsch, Amy K Ernst, Gail T Rogers, Cheryl H Gilhooly, Adrienne Hatch-McChesney, Caroline M Blanchard, Kara A Livingston, Rachel E Silver, Edward Martin, Susan M McGraw, Meghan K Chin, Taylor A Vail, Laura J Lutz, Scott J Montain, Anastassios G Pittas, Alice H Lichtenstein, David B Allison, Stephanie Dickinson, Xiwei Chen, Edward Saltzman, Andrew J Young, Susan B Roberts
doi : 10.1093/ajcn/nqab259
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1546–1559
Lifestyle interventions are the first-line treatment for obesity, but participant weight loss is typically low.
Factors associated with longitudinal changes in B-vitamin and choline concentrations of human milk
Mônica A Batalha, Ana L L Ferreira, Nathalia C Freitas-Costa, Amanda C C Figueiredo, Thais R B Carrilho, Setareh Shahab-Ferdows, Daniela Hampel, Lindsay H Allen, Rafael Pérez-Escamilla, Gilberto Kac
doi : 10.1093/ajcn/nqab191
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1560–1573
Little is known regarding the associations between maternal factors and B-vitamin and choline concentrations in early milk and the trajectories of these vitamins during lactation.
Corrigendum for Das et al. Randomized trial of a novel lifestyle intervention compared with the Diabetes Prevention Program for weight loss in adult dependents of military service members. Am J Clin Nutr 2021;114(4):1546–59.
doi : 10.1093/ajcn/nqab301
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Page 1574
Calendar of Events
doi : 10.1093/ajcn/nqab322
The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Page 1575
