One-year access to more than 500 world journals available in the system
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Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury
Susan E. Rowell, MD, MBA; Eric N. Meier, MS; Barbara McKnight, PhD; et al.
doi : 10.1001/jama.2020.8958
JAMA. 2020;324(10):961-974.
This randomized clinical trial compares the effects of an out-of-hospital tranexamic acid bolus vs placebo within 2 hours of traumatic brain injury (TBI) on 6-month functional neurologic outcome (Glasgow Coma Scale-Extended score >4) in patients with moderate or severe TBI.
Association Between Patient Social Risk and Physician Performance Scores in the First Year of the Merit-based Incentive Payment System
Dhruv Khullar, MD, MPP; William L. Schpero, PhD; Amelia M. Bond, PhD; et al.
doi : 10.1001/jama.2020.13129
JAMA. 2020;324(10):975-983.
This study uses data from the Medicare Physician Compare database to assess associations between patient social risk, defined as dual eligibility for Medicare and Medicaid, and physicians’ Merit-based Incentive Payment System (MIPS) data scores, a proxy for patient outcomes and care value.
Association of Clinician Health System Affiliation With Outpatient Performance Ratings in the Medicare Merit-based Incentive Payment System
Kenton J. Johnston, PhD; Timothy L. Wiemken, PhD; Jason M. Hockenberry, PhD; et al.
doi : 10.1001/jama.2020.13136
JAMA. 2020;324(10):984-992.
This study uses data from the Medicare Physician Compare database to assess associations between clinician affiliation with health systems and performance scores and value-based reimbursement under the 2019 Merit-based Incentive Payment System (MIPS).
Effect of an Inactivated Vaccine Against SARS-CoV-2 on Safety and Immunogenicity OutcomesInterim Analysis of 2 Randomized Clinical Trials
Shengli Xia, BS; Kai Duan, PhD; Yuntao Zhang, PhD; et al.
doi : 10.1001/jama.2020.15543
JAMA. 2020;324(10):951-960.
This interim analysis of 2 randomized trials compares adverse reactions and neutralizing antibody responses to inactivated coronavirus disease 2019 (COVID-19) vs adjuvant-only control vaccination, and compares the outcomes at varying vaccine doses among healthy adults in China.
Characteristics and Outcomes of COVID-19 Patients During Initial Peak and Resurgence in the Houston Metropolitan Area
Farhaan S. Vahidy, PhD, MBBS, MPH; Ashley L. Drews, MD; Faisal N. Masud, MD; et al.
doi : 10.1001/jama.2020.15301
JAMA. 2020;324(10):998-1000.
This study examined the sociodemographic and clinical characteristics of patients, as well as their clinical outcomes, during a surge in COVID-19 disease in Houston, Texas.
Allocation of COVID-19 Relief Funding to Disproportionately Black Counties
Pragya Kakani, AB; Amitabh Chandra, PhD; Sendhil Mullainathan, PhD; et al.
doi : 10.1001/jama.2020.14978
JAMA. 2020;324(10):1000-1003.
This study describes correlations between the dollar amount of relief funding authorized by the US Congress to fund prevention, diagnosis, and treatment of coronavirus disease 2019 (COVID-19) and to reimburse health care entities for lost revenues, and county-level Black population fraction accounting for county COVID-19 burden, comorbidity, and hospital financial health.
Hepatitis C–Related Hepatocellular Carcinoma Incidence in the Veterans Health Administration After Introduction of Direct-Acting Antivirals
Lauren A. Beste, MD, MSc; Pamela Green, PhD; Kristin Berry, PhD; et al.
doi : 10.1001/jama.2020.10121
JAMA. 2020;324(10):1003-1005
This study describes trends in the incidence of hepatocellular carcinoma within the Veterans Health Administration from 2002 to 2018 before and after widespread direct-acting anti–hepatitis C virus (HCV) treatment.
Unwavering Regulatory Safeguards for COVID-19 Vaccines
Anand Shah, MD; Peter W. Marks, MD, PhD; Stephen M. Hahn, MD
doi : 10.1001/jama.2020.15725
JAMA. 2020;324(10):931-932.
This Viewpoint from the FDA reviews the minimum safety and efficacy standards COVID-19 vaccine candidates would need to meet to be considered for approval, and affirms its commitments to evaluating both in diverse populations and to postmarketing surveillance as means to ensure that approval will meet the highest safety and regulatory standards based on science and evidence, not politics.
Precision Public Health as a Key Tool in the COVID-19 Response
Sonja A. Rasmussen, MD, MS; Muin J. Khoury, MD, PhD; Carlos del Rio, MD
doi : 10.1001/jama.2020.14992
JAMA. 2020;324(10):933-934.
This Viewpoint provides examples of how applying precision public health operations can help curb the COVID-19 pandemic.
Cascading Risks of COVID-19 Resurgence During an Active 2020 Atlantic Hurricane Season
James M. Shultz, MS, PhD; Craig Fugate; Sandro Galea, MD, DrPH
doi : 10.1001/jama.2020.15398
JAMA. 2020;324(10):935-936.
This Viewpoint discusses the prospects for exacerbation of the coronavirus disease 2019 (COVID-19) pandemic during hurricane season in the US, and proposes reinforcement of public health measures, clear communication, and learning from each experience to reduce the risks of hurricane-related harms and increases in COVID-19 cases.
Improving Physician Communication About Treatment DecisionsReconsideration of “Risks vs Benefits”
Daniel J. Morgan, MD; Laura D. Scherer, PhD; Deborah Korenstein, MD
doi : 10.1001/jama.2020.0354
JAMA. 2020;324(10):937-938.
This Viewpoint emphasizes the importance of precise language to help patients make evidence-informed decisions in shared decision-making, and argues that references to “chances of harms and benefits” will be more understandable to patients than discussions of “probabilities of risks and benefits.”
Over-the-Counter Oral Contraceptives to Reduce Unintended Pregnancies
Kunal K. Sindhu, MD; Eli Y. Adashi, MD, MS
doi : 10.1001/jama.2019.21862
JAMA. 2020;324(10):939-940.
This Viewpoint reviews progress and challenges to date in federal and state efforts to transition combination oral contraceptives (COCs) from being prescription only to over-the-counter status in the US.
The Silence and Sorrow of Miscarriage
Altaf Saadi, MD, MSc
doi : 10.1001/jama.2020.15959
JAMA. 2020;324(10):941-942.
In this narrative medicine essay, a neurologist relates the story of her miscarriage while touring immigration detention centers in Texas documenting medical care and human rights violations and shares her deep sorrow for the women who lost children either by force or miscarriages while incarcerated.
An Inactivated Virus Candidate Vaccine to Prevent COVID-19
Mark J. Mulligan, MD
doi : 10.1001/jama.2020.15539
JAMA. 2020;324(10):943-945.
Out-of-Hospital Tranexamic Acid for Traumatic Brain Injury
David C. Cone, MD; Daniel W. Spaite, MD; Timothy J. Coats, MBBS
doi : 10.1001/jama.2020.9244
JAMA. 2020;324(10):946-947.
Potential Adverse Financial Implications of the Merit-based Incentive Payment System for Independent and Safety Net Practices
Carrie H. Colla, PhD; Toyin Ajayi, MD, MPhil; Asaf Bitton, MD, MPH
doi : 10.1001/jama.2020.13093
JAMA. 2020;324(10):948-950.
Polymyalgia Rheumatica and Giant Cell Arteritis
Frank Buttgereit, MD; Eric L. Matteson, MD, MPH; Christian Dejaco, MD, PhD
doi : 10.1001/jama.2020.10155
JAMA. 2020;324(10):993-994.
This JAMA Insights Clinical Update reviews the diagnosis and management of polymyalgia rheumatica and giant cell arteritis and provides a suggested treatment algorithm for giant cell arteritis.
Decreased Exercise Tolerance in a Young Woman
Nicholas A. Oh, MD; John E. Mayer Jr, MD
doi : 10.1001/jama.2020.8415
JAMA. 2020;324(10):995-996.
A 31-year-old woman with a history of childhood heart murmur has exercise intolerance due to dyspnea, no chest pain, a fixed split S2 and a 2/6 systolic murmur at the left upper sternal border, and incomplete right bundle-branch block on ECG. Chest imaging shows increased vascularity, cardiomegaly, and an enlarged right atrium and right ventricle. What is the diagnosis and what would you do next?
What Happens When COVID-19 Collides With Flu Season?
doi : 10.1001/jama.2020.15260
JAMA. 2020;324(10):923-925.
This Medical News feature examines what might happen when COVID-19 meets seasonal influenza this fall.
Flu Vaccination Urged During COVID-19 Pandemic
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2020.15444
JAMA. 2020;324(10):926-927.
This Medical News article reports on efforts to increase flu vaccinations during the COVID-19 pandemic.
COVID-19 Precautions Helped Limit Cases Linked to Milwaukee Primary
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2020.16103
JAMA. 2020;324(10):929.
TB Control Suffers During Pandemic
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2020.15886
JAMA. 2020;324(10):929.
Antibiotic-Sparing Gonorrhea Diagnostic Wins Federal Funding
Jennifer Abbasi
doi : 10.1001/jama.2020.16465
JAMA. 2020;324(10):928.
Drug Repurposing Study Pinpoints Potential COVID-19 Antivirals
Jennifer Abbasi
doi : 10.1001/jama.2020.15948
JAMA. 2020;324(10):928.
New T-Cell Therapy Tested for Multiple Myeloma
Jennifer Abbasi
doi : 10.1001/jama.2020.16467
JAMA. 2020;324(10):928.
Dance for Respiratory Patients in Low-Resource Settings
Keir E. J. Philip, MRCP; Winceslaus Katagira, MD; Rupert Jones, MD
doi : 10.1001/jama.2020.15426
JAMA. 2020;324(10):921-922.
This Arts and Medicine feature describes the integration of local dance traditions into pulmonary rehabilitation programs for COPD and tuberculosis patients in low- and middle-income countries.
Moving Back to the Marriage Bed
Deborah Scaperoth, PhD
doi : 10.1001/jama.2020.7447
JAMA. 2020;324(10):1010.
Heart Failure
Jayson R. Baman, MD; Faraz S. Ahmad, MD, MS
doi : 10.1001/jama.2020.13310
JAMA. 2020;324(10):1015.
This JAMA Patient Page describes heart failure and its diagnosis, treatment options, and prevention measures.
Caring for Someone With COVID-19
Lindsey Y. Mortenson, MD; Preeti N. Malani, MD, MSJ; Robert D. Ernst, MD
doi : 10.1001/jama.2020.15061
JAMA. 2020;324(10):1016.
This JAMA Patient Page reviews the symptoms and signs of COVID-19, at-home management of the infection, and precautions to take while caring for someone with it.
Reconfiguring Medical Education
Hugh A. Stoddard, MEd, PhD
doi : 10.1001/jama.2020.10899
JAMA. 2020;324(10):1005-1006.
Reconfiguring Medical Education
Jennifer M. Connell, BS; Jan A. Niec, BS; Kayvon F. Sharif, BA
doi : 10.1001/jama.2020.10902
JAMA. 2020;324(10):1006.
Reconfiguring Medical Education
Daniel Yim
doi : 10.1001/jama.2020.10896
JAMA. 2020;324(10):1006-1007.
Reconfiguring Medical Education
George D. Everett, MD; Michael Muszynski, MD
doi : 10.1001/jama.2020.10905
JAMA. 2020;324(10):1007.
Reconfiguring Medical Education—Reply
Ezekiel J. Emanuel, MD, PhD
doi : 10.1001/jama.2020.10908
JAMA. 2020;324(10):1007-1008.
Chikungunya Virus–Like Particle Vaccine
Nishant Jaiswal, MBBS, PhD; Shreya Singh, MD; Meenu Singh, MD
doi : 10.1001/jama.2020.11845
JAMA. 2020;324(10):1008.
Chikungunya Virus–Like Particle Vaccine—Reply
Grace L. Chen, MD, MPH
doi : 10.1001/jama.2020.11859
JAMA. 2020;324(10):1008-1009.
Correction to Affiliations in Arts and Medicine Feature
doi : 10.1001/jama.2020.15817
JAMA. 2020;324(10):1009.
