European Heart Journal




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The ESC Guidelines on cardiovascular prevention and a focus on old and new risk factors 

Filippo Crea

doi : 10.1093/eurheartj/ehab577

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3209–3213

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Impact Factor of the European Heart Journal: update, interpretation, and perspectives 

Filippo Crea

doi : 10.1093/eurheartj/ehab492

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3214–3215

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The role of sex and gender differences in precision medicine: the work of the Women’s Brain Project 

Annemarie Schumacher Dimech, Maria Teresa Ferretti, Else C Sandset, Antonella Santuccione Chadha

doi : 10.1093/eurheartj/ehab297

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3215–3217

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Cardio Ultraefficient nanoParticles for Inhalation of Drug prOducts: when CUPIDO hits the nano-revolution in cardiology 

Daniele Catalucci

doi : 10.1093/eurheartj/ehab266

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3217–3220

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Interventional cardiology’s cross-departmental effort with production of reusable personal protective equipment during the early phase of COVID-19 pandemic 

Sehrish Memon, Evan Friend, Jon C George, Sanjog Kalra

doi : 10.1093/eurheartj/ehab289

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3220–3223

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Occluding to prevent occlusion 

Giovanna Liuzzo, Carlo Patrono

doi : 10.1093/eurheartj/ehab464

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3224–3225

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2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC) 

Frank L J Visseren, François Mach, Yvo M Smulders, David Carballo, Konstantinos C Koskinas, Maria B?ck, Athanase Benetos, Alessandro Biffi, José-Manuel Boavida, Davide Capodanno, Bernard Cosyns, Carolyn Crawford, Constantinos H Davos, Ileana Desormais, Emanuele Di Angelantonio, Oscar H Franco, Sigrun Halvorsen, F D Richard Hobbs, Monika Hollander, Ewa A Jankowska, Matthias Michal, Simona Sacco, Naveed Sattar, Lale Tokgozoglu, Serena Tonstad, Konstantinos P Tsioufis, Ineke van Dis, Isabelle C van Gelder, Christoph Wanner, Bryan Williams, ESC Scientific Document Group

doi : 10.1093/eurheartj/ehab484

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3227–3337

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Persisting burden and challenges of rheumatic heart disease 

Eloi Marijon, Ana Mocumbi, Kumar Narayanan, Xavier Jouven, David S Celermajer

doi : 10.1093/eurheartj/ehab407

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3338–3348

Rheumatic heart disease (RHD) is the result of episodes of acute rheumatic fever with valvular (and other cardiac) damage caused by an abnormal immune response to group A streptococcal infections, usually during childhood and adolescence. As a result of improved living conditions and the introduction of penicillin, RHD was almost eradicated in the developed world by the 1980s. However, being a disease of poverty, its burden remains disproportionately high in the developing world, despite being a fundamentally preventable disease. Rheumatic heart disease generates relatively little attention from the medical and science communities, in contrast to other common infectious problems (such as malaria, HIV, tuberculosis), despite the major cardiovascular morbidity/mortality burden imposed by RHD. This relative neglect and paucity of funding have probably contributed to limited fundamental medical advances in this field for over 50?years. Given the importance of prevention before the onset of major valvular damage, the main challenges for RHD prevention are improving social circumstances, early diagnosis, and effective delivery of antibiotic prophylaxis. Early identification through ultrasound of silent, subclinical rheumatic valve lesions could provide an opportunity for early intervention. Simple echocardiographic diagnostic criteria and appropriately trained personnel can be valuable aids in large-scale public health efforts. In addition, a better understanding of the immunogenic determinants of the disease may provide potential routes to vaccine development and other novel therapies.

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Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank

Sizhi Ai, Jihui Zhang, Guoan Zhao, Ningjian Wang, Guohua Li, Hon-Cheong So, Yaping Liu, Steven Wai-Ho Chau, Jie Chen, Xiao Tan, Fujun Jia, Xiangdong Tang, Jie Shi, Lin Lu, Yun-Kwok Wing

doi : 10.1093/eurheartj/ehab170

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3349–3357

Observational studies have suggested strong associations between sleep duration and many cardiovascular diseases (CVDs), but causal inferences have not been confirmed. We aimed to determine the causal associations between genetically predicted sleep duration and 12 CVDs using both linear and nonlinear Mendelian randomization (MR) designs.

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Longer sleep improves cardiovascular outcomes: time to make sleep a priority 

Tamar Sofer, Matthew O Goodman, Suzanne M Bertisch, Susan Redline

doi : 10.1093/eurheartj/ehab248

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3358–3360

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Mammographic features are associated with cardiometabolic disease risk and mortality 

Felix Grassmann, Haomin Yang, Mikael Eriksson, Shadi Azam, Per Hall, Kamila Czene

doi : 10.1093/eurheartj/ehab502

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3361–3370

In recent years, microcalcifications identified in routine mammograms were found to be associated with cardiometabolic disease in women. Here, we aimed to systematically evaluate the association of microcalcifications and other mammographic features with cardiometabolic disease risk and mortality in a large screening cohort and to understand a potential genetic contribution.

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Mammograms to catch many birds with one stone 

Angela H E M Maas, Pim A de Jong

doi : 10.1093/eurheartj/ehab522

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3371–3373

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Lifestyle, cardiometabolic disease, and multimorbidity in a prospective Chinese study 

Yuting Han, Yizhen Hu, Canqing Yu, Yu Guo, Pei Pei, Ling Yang, Yiping Chen, Huaidong Du, Dianjianyi Sun, Yuanjie Pang, Ningyu Chen, Robert Clarke, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, on behalf of the China Kadoorie Biobank Collaborative Group

doi : 10.1093/eurheartj/ehab413

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3374–3384

The potential difference in the impacts of lifestyle factors (LFs) on progression from healthy to first cardiometabolic disease (FCMD), subsequently to cardiometabolic multimorbidity (CMM), and further to death is unclear.

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Key roles of five lifestyle risk factors in the harmful transition from a healthy condition to multimorbidity in the Chinese population 

Dong Zhao

doi : 10.1093/eurheartj/ehab516

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3385–3387

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Association between adiposity and cardiovascular outcomes: an umbrella review and meta-analysis of observational and Mendelian randomization studies 

Min Seo Kim, Won Jun Kim, Amit V Khera, Jong Yeob Kim, Dong Keon Yon, Seung Won Lee, Jae Il Shin, Hong-Hee Won

doi : 10.1093/eurheartj/ehab454

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3388–3403

The aim of this study was to investigate the causal relationship and evidence of an association between increased adiposity and the risk of incident cardiovascular disease (CVD) events or mortality.

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Obesity and cardiovascular health: the size of the problem 

Annika Rosengren

doi : 10.1093/eurheartj/ehab518

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3404–3406

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Clinical and methodological considerations when interpreting meta-analyses of beta-blocker use in patients with chronic obstructive pulmonary disease 

Claudia Gulea, Jennifer K. Quint, Rosita Zakeri

doi : 10.1093/eurheartj/ehab217

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Pages 3407–3408

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Increasing the prescription rate of ?-blockers is beneficial for patients with chronic obstructive pulmonary and cardiovascular disease 

Yan-Li Yang, Zi-Jian Xiang, Ruo-Lan Xiang

doi : 10.1093/eurheartj/ehab239

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Page 3409

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Bridging inflammation

Nicola Gaibazzi, Domenico Tuttolomondo, Damini Dey, Giampaolo Niccoli

doi : 10.1093/eurheartj/ehaa901

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Page 3384

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Balloon pulmonary angioplasty with distal embolic protection device for chronic thromboembolic pulmonary hypertension

Ting-Ting Guo, Jiang-Shan Tan, Yan Wu, Xin Gao, Chao-Wu Yan, Shi-Guo Li, Lu Hua

doi : 10.1093/eurheartj/ehaa932

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Page 3408

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Aortic intimo-intimal intussusception in Stanford type A acute aortic dissection

Aleksander Dokollari, Matteo Cameli, Louie Wang, Gianluigi Bisleri

doi : 10.1093/eurheartj/ehaa886

European Heart Journal, Volume 42, Issue 34, 7 September 2021, Page 3410

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