American Heart Journal




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Table of Contents

doi : 10.1016/S0002-8703(21)00170-8

Volume 239, September 2021, Pages i-ii

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Editorial Board

doi : 10.1016/S0002-8703(21)00171-X

Volume 239, September 2021, Page iii

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Information for Readers

doi : 10.1016/S0002-8703(21)00172-1

Volume 239, September 2021, Page iv

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Potential impact of the steroid hormone, vitamin D, on the vasculature

YinTintutPhDabcLinda L.DemerMD, PhDabde

doi : 10.1016/j.ahj.2021.05.012

Volume 239, September 2021, Pages 147-153

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A prospective multicenter validation study for a novel angiography-derived physiological assessment software: Rationale and design of the radiographic imaging validation and evaluation for Angio-iFR (ReVEAL iFR) study

MasafumiOnoMDabPatrick W.SerruysMD, PhDbcManesh R.PatelMDdJavierEscanedMD, PhDeTakashiAkasakaMD, PhDfMartijn A. vanLavierenMScagChristianHaasePhDgMichaelGrassPhDgNorihiroKogameMDaHironoriHaraMDabHideyukiKawashimaMDabJoanna J.WykrzykowskaMD, PhDhJan J.PiekMD, PhDaScotGargMD, PhDiNeilO'LearyPhDbBeckyInderbitzenMSEgYoshinobuOnumaMD, PhDb

doi : 10.1016/j.ahj.2021.05.004

Volume 239, September 2021, Pages 19-26

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Rationale and design of the intravenous iron for treatment of anemia before cardiac surgery trial

Paul S.MylesMPH, DScabTobyRichardsBSc, MDbcAndrewKleinMBBS, FRCAbdJulianSmithMBBS, MSefErica M.WoodMBBS, FRACPghStephaneHeritierMMath, PhDhDavidMcGiffinFRACSiSilvaZavarsekPhDjJoelSymonsMBBCh, FANZCAabZoe K.McQuiltenMBBS, FRACPghRobert A.BakerPhD, CCPkKeyvanKarkoutiMSc, MDlSophiaWallaceBSc, MPHabthe ANZCA Clinical Trials Network

doi : 10.1016/j.ahj.2021.05.008

Volume 239, September 2021, Pages 64-72

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Batch enrollment for an artificial intelligence-guided intervention to lower neurologic events in patients with undiagnosed atrial fibrillation: rationale and design of a digital clinical trial

XiaoxiYaoPhD12Zachi I.AttiaMS2Emma M.Behnken3KelliWalvatneMBA1Rachel E.GiblonMS4SijiaLiuPhD4Konstantinos C.SiontisMD2Bernard J.GershMB, ChB, DPhil2JonathanGraff-RadfordMD5Alejandro A.RabinsteinMD5Paul A.FriedmanMD2Peter A.NoseworthyMD2

doi : 10.1016/j.ahj.2021.05.006

Volume 239, September 2021, Pages 73-79

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Study design and rationale of VALOR-HCM: evaluation of mavacamten in adults with symptomatic obstructive hypertrophic cardiomyopathy who are eligible for septal reduction therapy

Milind Y.DesaiMD, MBAabcKathyWolskiMPHbcAnjaliOwensMDdeSrihari S.NaiduMDfJeffrey B.GeskeMDgNicholas G.SmediraMD, MBAadHartzellSchaffMDhKathyLamplMDiEllenMcErleanRNbcChristinaSewellRNbcDavidZhangPhDiJay M.EdelbergMD, PhDiAmy J.SehnertMDiSteven E.NissenMDbc

doi : 10.1016/j.ahj.2021.05.007

Volume 239, September 2021, Pages 80-89

Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder which frequently leads to symptoms such as dyspnea and exercise intolerance, often due to severe dynamic left ventricular outflow tract obstruction (LVOTO). Current guideline-recommended pharmacotherapies have variable therapeutic responses to relieve LVOTO. In recent phases 2 and 3, clinical trials for symptomatic obstructive HCM (oHCM), mavacamten, a small molecule inhibitor of ?-cardiac myosin has been shown to improve symptoms, exercise capacity, health status, reduce LVOTO, along with having a beneficial impact on cardiac structure and function.

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Catheter-based alcohol-mediated renal denervation for the treatment of uncontrolled hypertension: design of two sham-controlled, randomized, blinded trials in the absence (TARGET BP OFF-MED) and presence (TARGET BP I) of antihypertensive medications

FelixMahfoudMD, PhDaMichaelWeberMD, PhDbRoland E.SchmiederMD, PhDcMelvin D.LoboMD, PhDdPeter J.BlankestijnMDeAlexandrePersuMD, PhDfTim A.FischellMDgHelenPariseScDhAtulPathakMD, PhDiDavid E.KandzariMDj

doi : 10.1016/j.ahj.2021.05.015

Volume 239, September 2021, Pages 90-99

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Sacubitril/valsartan versus enalapril on exercise capacity in patients with heart failure with reduced ejection fraction: A randomized, double-blind, active-controlled study

Marcelo Rodriguesdos SantosPhDaMaria-Janieire de Nazaré NunesAlvesMD, PhDaCamila Paix?oJord?oMScaCaio Eduardo NovaesPintoMScaKelly Thayane SouzaCorreaPhDaFrancis Ribeirode SouzaPhDaGuilherme Wesley Peixotoda FonsecaPhDaJoaquimTomaz FilhoBPaMarcelCostaMDaRosa Maria RodriguesPereiraMD, PhDbCarlos EduardoNegr?oPhDacAntônio Carlos PereiraBarrettoMD, PhDa

doi : 10.1016/j.ahj.2021.05.005

Volume 239, September 2021, Pages 1-10

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Advanced heart failure patients supported with ambulatory inotropic therapy: What defines success of therapy?

Christopher S.GrubbMDaLauren K.TrubyMDbVeli K.TopkaraMDaMichael S.BohnenMD, PhDaMelanaYuzefpolskayaMDaErsilia M.DeFilippisMDaAudreyKleetNPaShunichiNakagawaMDaJennifer H.HaytheMDaKellyAxsomMDaPaoloColomboMDaKojiTakedaMD, PhDcNirUrielMD, MScaGabrielSayerMDaHasanGaranMDaYoshifumiNakaMD, PhDcMaryjaneFarrMD, MSca

doi : 10.1016/j.ahj.2021.05.001

Volume 239, September 2021, Pages 11-18

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Depressive hypertension: A proposed human endotype of brain/gut microbiome dysbiosis

Bruce R.StevensPhDabc#Carl J.PepineMDd#Elaine M.RichardsPhDa#SeungbumKimPhDa#Mohan K.RaizadaPhDa#

doi : 10.1016/j.ahj.2021.05.002

Volume 239, September 2021, Pages 27-37

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The impact of a population-based prevention program on cardiovascular events: Findings from the heart of new Ulm project

Abbey C.SidebottomMPH, PhDaMichael D.MiedemaMD, MPHbcGretchenBensonBAbMarcVacquierMSaJeffrey J.VanWormerPhDdArthurSillahMPH, PhDeRebeccaLindbergMPHbJackie L.BoucherMSfSteven M.BradleyMD, MPHbc

doi : 10.1016/j.ahj.2021.04.010

Volume 239, September 2021, Pages 38-51

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Sarcopenia in cardiac surgery: Dual X-ray absorptiometry study from the McGill frailty registry

AayushiJoshiMScabRitaManciniMScabStephanProbstMDcGadAbikhzerMDcYvesLangloisMDdJean-FrancoisMorinMDdLawrence GRudskiMDeJonathanAfilaloMD, MSc, FACC, FRCPCabe

doi : 10.1016/j.ahj.2021.04.008

Volume 239, September 2021, Pages 52-58

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Estimating the real-world performance of the PROMISE minimal-risk tool

MGNannaMD, MHSaTYWangMD, MHSaKChiswellPhDaJLSunMSaSVemulapalliMDaUHoffmannMD, MPHbMRPatelMDaJEUdelsonMDcCBFordyceMD, MHS, MScdPSDouglasMDa

doi : 10.1016/j.ahj.2021.05.016

Volume 239, September 2021, Pages 100-109

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Early diuretic strategies and the association with In-hospital and Post-discharge outcomes in acute heart failure

MaratFudimMD, MHSabToiSpatesMDbJie-LenaSunMSaVeraprapasKittipibulMDcJeffrey M.TestaniMDdRandall C.StarlingMDeW.H. WilsonTangMDeAdrian F.HernandezMDabG. MichaelFelkerMD, MHSabChristopher M.O'ConnorMDfRobert J.MentzMDab

doi : 10.1016/j.ahj.2021.05.011

Volume 239, September 2021, Pages 110-119

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Pre-operative atrial fibrillation and early right ventricular failure after left ventricular assist device implantation: a systematic review and meta-analysis

VeraprapasKittipibulMDaVanessaBlumerMDbGabriel A.HernandezMDcMaratFudimMD, MHSbRobertFlowersMDaSandraChaparroMDdRichaAgarwalMDb

doi : 10.1016/j.ahj.2021.05.009

Volume 239, September 2021, Pages 120-128

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Simplifying the ISCHEMIA trial algorithm for clinical practice: Identifying left main coronary artery disease using coronary artery calcium scans

Joel E.MoneyMDabJoseph B.MuhlesteinMDabSteveMasonPA-CaTami L.BairaKirk U.KnowltonMDabBenjamin D.HornePhD, MStat, MPHacJeffrey L.AndersonMDab

doi : 10.1016/j.ahj.2021.05.013

Volume 239, September 2021, Pages 129-134

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The association of healthcare disparities and patient-specific factors on clinical outcomes in peripheral artery disease

Dennis I.NarcisseMD, MSaCassie B.FordPhDbE. HopeWeisslerMDcdSteven J.LippmannPhDbMichelle M.SmerekBSbMelissa A.GreinerMSbN. ChantelleHardyMPHbBenjaminO'BrienBSbR. CaseySullivanMDeAdam J.BrockMDfChandlerLongMDdLesley H.CurtisPhDbcManesh R.PatelMDacW. SchuylerJonesMDac

doi : 10.1016/j.ahj.2021.05.014

Volume 239, September 2021, Pages 135-146

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Effect of once-weekly exenatide on hospitalization for acute coronary syndrome or coronary revascularization in patients with type 2 diabetes mellitus

Carlos E.BarberyMDaAnnaGiczewskaMSbJenniferWhiteMSbYuliyaLokhnyginaPhDbRobert JohnMentzMDabRury R.HolmanMB ChBcNehaPagidipatiMDabAdrian F.HernandezMDabW. SchuylerJonesMDab

doi : 10.1016/j.ahj.2021.03.013

Volume 239, September 2021, Pages 59-63

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