The Lancet




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2025: an annus horribilis for health in the USA

doi : 10.1016/S0140-6736(25)02588-7

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Oral small-molecule GLP-1 receptor agonist for type 2 diabetes and obesity

doi : 10.1016/S0140-6736(25)02381-5

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Neoadjuvant quadruplet chemotherapy PAXG for pancreatic cancer

doi : 10.1016/S0140-6736(25)01864-1

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Methoxyflurane: a promising non-intravenous, non-opioid analgesic

doi : 10.1016/S0140-6736(25)01532-6

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Exploring CAR NK-cell therapy for refractory lupus

doi : 10.1016/S0140-6736(25)01949-X

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US CDC: a public health agency in critical condition

doi : 10.1016/S0140-6736(25)02353-0

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The 2025 Wakley Prize: finding a home in medicine

doi : 10.1016/S0140-6736(25)02553-X

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Grants under threat at the US National Institutes of Health

doi : 10.1016/S0140-6736(25)02590-5

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UN Environmental Assembly passes AMR resolution

doi : 10.1016/S0140-6736(25)02591-7

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Southeast Asia reels after tropical storms

doi : 10.1016/S0140-6736(25)02592-9

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Highlights 2025: illuminating health stories

doi : 10.1016/S0140-6736(25)02550-4

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Darfur's humanitarian emergency: a call for immediate action

doi : 10.1016/S0140-6736(25)02383-9

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Gender-based violence and displacement in Darfur's war

doi : 10.1016/S0140-6736(25)02384-0

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Russia's health workers complicit in abducting Ukraine's children

doi : 10.1016/S0140-6736(25)02388-8

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Cerebral palsy: an update on its early detection

doi : 10.1016/S0140-6736(25)02310-4

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Cerebral palsy: an update on its early detection – Authors' reply

doi : 10.1016/S0140-6736(25)02311-6

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The need for metabolic health stratification in global obesity forecasts

doi : 10.1016/S0140-6736(25)01234-6

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The need for metabolic health stratification in global obesity forecasts – Authors' reply

doi : 10.1016/S0140-6736(25)02312-8

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The diabetic foot after SWHSI-2: healing is not one size fits all

doi : 10.1016/S0140-6736(25)02070-7

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The diabetic foot after SWHSI-2: healing is not one size fits all – Authors' reply

doi : 10.1016/S0140-6736(25)02247-0

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Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial

doi : 10.1016/S0140-6736(25)02165-8

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Preoperative mFOLFIRINOX versus PAXG for stage I–III resectable and borderline resectable pancreatic ductal adenocarcinoma (PACT-21 CASSANDRA): results of the first randomisation analysis of a randomised, open-label, 2 × 2 factorial phase 3 trial

doi : 10.1016/S0140-6736(25)01685-X

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Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial

doi : 10.1016/S0140-6736(25)01575-2

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Efficacy and safety of allogeneic CD19 CAR NK-cell therapy in systemic lupus erythematosus: a case series in China

doi : 10.1016/S0140-6736(25)01671-X

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Amylin and the renin-angiotensin system: risk or opportunity in amylin-based therapy?

doi : 10.1016/S0140-6736(25)01776-3

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Lessons from Africa: health diplomacy in HIV prevention

doi : 10.1016/S0140-6736(25)01976-2

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