Journal of the American College of Cardiology




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Ideas Worth Testing: The Adipokine Hypothesis

doi : 10.1016/j.jacc.2025.08.004

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Adiposity at the Core of Cardiometabolic Disease: A Turning Point

doi : 10.1016/j.jacc.2025.08.056

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Do Heart Failure With Preserved Ejection Fraction Treatments Work by Targeting Adipose Biology?

doi : 10.1016/j.jacc.2025.07.046

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Adipokine–Cardiomyocyte Crosstalk: A 2-Way Street in HFpEF Pathogenesis?

doi : 10.1016/j.jacc.2025.08.055

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HFpEF in East Asia: Does the Adipokine Hypothesis Hold?

doi : 10.1016/j.jacc.2025.08.034

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The Adipokine Hypothesis of HFpEF: A Bold Unifying Framework in Need of Translational Proof

doi : 10.1016/j.jacc.2025.09.005

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Body Composition and Treatment Response in Heart Failure With Preserved Ejection Fraction: Interpreting the Adipokine Hypothesis

doi : 10.1016/j.jacc.2025.08.037

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It's About Sex, Not Just Fat: Interpreting the Adipokine Hypothesis in the Context of Sex Differences in HFpEF

doi : 10.1016/j.jacc.2025.08.038

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On the Adipokines Hypothesis: Toward a Mechanism-Guided Reframing of HFpEF

doi : 10.1016/j.jacc.2025.07.065

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Adipokine Signaling in Heart Failure With Preserved Ejection Fraction: A New Clinical Frontier

doi : 10.1016/j.jacc.2025.07.045

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The Adipokine Hypothesis of Heart Failure With a Preserved Ejection Fraction: A Novel Framework to Explain Pathogenesis and Guide Treatment

doi : 10.1016/j.jacc.2025.06.055

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