One-year access to more than 500 world journals available in the system
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Effect of Intraoperative Low Tidal Volume vs Conventional Tidal Volume on Postoperative Pulmonary Complications in Patients Undergoing Major SurgeryA Randomized Clinical Trial
Dharshi Karalapillai, MD; Laurence Weinberg, MD; Philip Peyton, MD; et al.
doi : 10.1001/jama.2020.12866
JAMA. 2020;324(9):848-858.
This randomized clinical trial compares the effect of intraoperative ventilation with low vs conventional tidal volume (6 vs 10 mL/kg predicted body weight) on pulmonary complications in the first 7 postoperative days among patients undergoing major surgery lasting longer than 2 hours.
Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US
Katherine A. Auger, MD, MSc; Samir S. Shah, MD, MSCE; Troy Richardson, PhD; et al.
doi : 10.1001/jama.2020.14348
JAMA. 2020;324(9):859-870.
This population epidemiology study estimates associations of school closures in the US and the timing of those closures in March 2020 with change in daily coronavirus disease 2019 (COVID-19) incidence and mortality through the first week of May, accounting for other contemporaneous public health interventions.
Association of New-Onset Atrial Fibrillation After Noncardiac Surgery With Subsequent Stroke and Transient Ischemic Attack
Konstantinos C. Siontis, MD; Bernard J. Gersh, MB, ChB, DPhil; Susan A. Weston, MS; et al.
doi : 10.1001/jama.2020.12518
JAMA. 2020;324(9):871-878.
This retrospective study compared the rate of ischemic stroke or transient ischemic attack among Olmstead County, Minnesota, residents with vs without new-onset postoperative atrial fibrillation after undergoing noncardiac surgery.
Prevalence of SARS-CoV-2 Antibodies in Health Care Personnel in the New York City Area
Joseph Moscola, PA, MBA; Grace Sembajwe, DSc, MSc, CIH; Mark Jarrett, MD, MBA, MS; et al.
doi : 10.1001/jama.2020.14765
JAMA. 2020;324(9):893-895.
This seroprevalence survey study describes severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity among health care workers at a New York City–based health system by age, sex, race, county of residence, and prior PCR-confirmed viral exposure.
Incidence of Malformations After Early Pregnancy Exposure to Modafinil in Sweden and Norway
Carolyn E. Cesta, PhD; Anders Engeland, PhD; P?r Karlsson, MSc; et al.
doi : 10.1001/jama.2020.9840
JAMA. 2020;324(9):895-897.
This pharmacoepidemiology study uses Scandinavian birth registry data to estimate the association between modafinil use during early pregnancy and major congenital malformations among infants born in Norway and Sweden between 2005-2006 and 2016-2017.
Reopening K-12 Schools During the COVID-19 PandemicA Report From the National Academies of Sciences, Engineering, and Medicine
Kenne A. Dibner, PhD; Heidi A. Schweingruber, PhD; Dimitri A. Christakis, MD, MPH
doi : 10.1001/jama.2020.14745
JAMA. 2020;324(9):833-834.
This Viewpoint summarizes recommendations made in a National Academies of Sciences, Engineering, and Medicine report about how to safely reopen and operate elementary and secondary schools for the 2020-2021 school year, which emphasizes the need for partnerships with public health officials and community leaders, and for transparent communication of risks and rewards that will result from every policy decision.
Women Physicians and the COVID-19 Pandemic
Linda Brubaker, MD
doi : 10.1001/jama.2020.14797
JAMA. 2020;324(9):835-836.
This Viewpoint describes how the COVID-19 pandemic has made more obvious the work-life imbalance inherent in the practice of medicine and how the moment offers the profession the chance to recalibrate gender role stereotypes that have traditionally disadvantaged the careers of women physicians and researchers.
Universal Masking in the United StatesThe Role of Mandates, Health Education, and the CDC
Lawrence O. Gostin, JD; I. Glenn Cohen, JD; Jeffrey P. Koplan, MD, MPH
doi : 10.1001/jama.2020.15271
JAMA. 2020;324(9):837-838.
This Viewpoint proposes legal and policy options for promoting universal face mask wearing in the US and, recognizing the limits of state-by-state implementation, proposes strengthening the authority, independence, and funding of the CDC to enact responses to this and future comparable public health emergencies.
National Hospital Quality RankingsImproving the Value of Information in Hospital Rating Systems
Jonathan A. Bae, MD; Lesley H. Curtis, PhD; Adrian F. Hernandez, MD, MHS
doi : 10.1001/jama.2020.11165
JAMA. 2020;324(9):839-840.
This Viewpoint uses US News & World Report’s annual hospital rankings to discuss how such efforts typically disadvantage hospitals caring for patients of lower socioeconomic status (SES) in regions with poorer population health, and argues for transparent and accurate ratings methods that use patient-centric quality measures and account for population SES.
Progress in Multiple Sclerosis ResearchAn Example of Bedside to Bench
Stephen L. Hauser, MD
doi : 10.1001/jama.2020.1522
JAMA. 2020;324(9):841-842
This Viewpoint attributes improved understanding of the role of autoantibodies and B-cell activity in MS pathogenesis and the development of effective therapies to the ability of physician-scientists to bring clinical insights to laboratory research and it emphasizes the importance of supporting and encouraging these investigators to reinvigorate science at the bedside.
Non Sei Solo
Mark C. Henderson, MD
doi : 10.1001/jama.2020.14420
JAMA. 2020;324(9):843-844.
In this narrative medicine essay a father recalls the traumatic death of his healthy young son and the steps he and his family took to overcome their guilt, repair their relationships, and honor the boy’s life.
COVID-19 and School Closures
Julie M. Donohue, PhD; Elizabeth Miller, MD, PhD
doi : 10.1001/jama.2020.13092
JAMA. 2020;324(9):845-847.
Benefits and Risks of Bariatric Surgery in AdultsA Review
David E. Arterburn, MD, MPH; Dana A. Telem, MD, MPH; Robert F. Kushner, MD; et al.
doi : 10.1001/jama.2020.12567
JAMA. 2020;324(9):879-887.
Precis This narrative review summarizes the efficacy and safety of bariatric surgery, mainly sleeve gastrectomy and the Roux-en-Y procedure, in assisting weight loss and in patients with type 2 diabetes and other obesity-related comorbidities.
Primary Care Treatment of Patients Following Bariatric Surgery in 2020
Yijun Chen, MD; Zhaoping Li, MD; Erik Dutson, MD
doi : 10.1001/jama.2020.14061
JAMA. 2020;324(9):888-889
This JAMA Insights Clinical Update reviews long-term complications of bariatric surgery, including GERD, gallstones, hypoglycemia, substance use disorder, and vitamin and other nutritional deficiencies, and proposes a schedule of testing and management strategies for each.
Rimegepant (Nurtec ODT) for Acute Treatment of Migraine
doi : 10.1001/jama.2020.8493
JAMA. 2020;324(9):890-891.
This Medical Letter review summarizes evidence supporting the use of rimegepant (Nurtec), a small-molecule calcitonin gene-related peptide receptor antagonist, for acute treatment of migraine with or without aura in adults.
Researchers Strive to Recruit Hard-Hit Minorities Into COVID-19 Vaccine Trials
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2020.11244
JAMA. 2020;324(9):826-828.
This Medical News article discusses efforts to ensure participation of racial and ethnic minorities in clinical trials of COVID-19 vaccines.
New FDA-EPA Protocol Covers Agricultural Water Safety
Rebecca Voelker, MSJ
doi : 10.1001/jama.2020.15848
JAMA. 2020;324(9):832.
CAR-T Therapy Is Approved for Mantle Cell Lymphoma
Rebecca Voelker, MSJ
doi : 10.1001/jama.2020.15456
JAMA. 2020;324(9):832.
FDA Targets Illegal Hangover Relief
Rebecca Voelker, MSJ
doi : 10.1001/jama.2020.15849
JAMA. 2020;324(9):832.
The Importance of Reestablishing a Pandemic Preparedness Office at the White House
Gail Wilensky, PhD
doi : 10.1001/jama.2020.15525
JAMA. 2020;324(9):830-831.
RNA Aptamers Deliver Chemotherapy Directly to Tumors
Tracy Hampton, PhD
doi : 10.1001/jama.2020.14464
JAMA. 2020;324(9):829.
Sleeve Gastrectomy
Brian C. Brajcich, MD, MS; Eric S. Hungness, MD
doi : 10.1001/jama.2020.14775
JAMA. 2020;324(9):908.
This JAMA Patient Page explains who should undergo gastric sleeve procedure, a type of obesity surgery; how to prepare for it; and what to expect afterward.
Reducing Vasopressor Exposure in Patients With Vasodilatory Hypotension
Saurabh Kumar Das, MD, PDCC, EDIC; Nang Sujali Choupoo, MD, PDCC; Sumit Ray, MD
doi : 10.1001/jama.2020.9216
JAMA. 2020;324(9):897-898.
Reducing Vasopressor Exposure in Patients With Vasodilatory Hypotension—Reply
François Lamontagne, MD; Paul R. Mouncey, MSc
doi : 10.1001/jama.2020.9219
JAMA. 2020;324(9):898-899.
Nonalcoholic Steatohepatitis
Martin M. Grajower, MD
doi : 10.1001/jama.2020.10434
JAMA. 2020;324(9):899.
Nonalcoholic Steatohepatitis—Reply
Adam C. Sheka, MD; Bilal Hameed, MD; Sayeed Ikramuddin, MD, MHA
doi : 10.1001/jama.2020.10437
JAMA. 2020;324(9):899-900.
Payer Mix Among Patients Receiving Dialysis
Eugene Lin, MD, MS; Kevin F. Erickson, MD, MS
doi : 10.1001/jama.2020.10771
JAMA. 2020;324(9):900-901.
Payer Mix Among Patients Receiving Dialysis—Reply
Abby Hoffman, BA; Matthew L. Maciejewski, PhD; Virginia Wang, PhD
doi : 10.1001/jama.2020.10774
JAMA. 2020;324(9):901.
