New England Journal of Medicine




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Physicians, Corporatization, and the Unmeasured Quality of Care

doi : 10.1056/NEJMp2415488

Volume 394 No. 13 April 2, 2026

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The Age Illusion — Limitations of Chronologic Age in Medicine

doi : 10.1056/NEJMp2516973

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Therapy’s Conversion — Chiles v. Salazar’s Threat to Mental Health Treatment and Standards of Care

doi : 10.1056/NEJMp2516723

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Perioperative Enfortumab Vedotin and Pembrolizumab in Bladder Cancer

doi : 10.1056/NEJMoa2511674

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Left Atrial Appendage Closure or Medical Therapy in Atrial Fibrillation

doi : 10.1056/NEJMoa2513310

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CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat Sickle Cell Disease

doi : 10.1056/NEJMoa2415550

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CRISPR-Cas12a Gene Editing of HBG1 and HBG2 Promoters to Treat β-Thalassemia

doi : 10.1056/NEJMoa2501277

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Discontinuation of Beta-Blocker Therapy after Myocardial Infarction

doi : 10.1056/NEJMoa2601005

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Clinical Examination of the Lumbar Spine

doi : 10.1056/NEJMvcm2402306

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Minocycline-Induced Hyperpigmentation

doi : 10.1056/NEJMicm2513782

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Enfortumab Vedotin plus Pembrolizumab as Perioperative Therapy

doi : 10.1056/NEJMe2515777

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Left Atrial Appendage Closure — Another Overused Method in Cardiology?

doi : 10.1056/NEJMe2518067

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More Options for Gene Editing in Hemoglobinopathies

doi : 10.1056/NEJMe2602194

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Liver Transplantation in Alcohol-Related Liver Disease

doi : 10.1056/NEJMclde2506067

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Digital Twin–Guided Ablation for Ventricular Tachycardia

doi : 10.1056/NEJMc2517822

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Simulating and Teaching the Physiology of Pulsus Paradoxus

doi : 10.1056/NEJMc2518685

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The Fetal-to-Adult Hemoglobin Switch — Mechanism and Therapy

doi : 10.1056/NEJMx250010

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Trastuzumab Deruxtecan in Residual HER2-Positive Early Breast Cancer

doi : 10.1056/NEJMx260006

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