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Issue Highlights page
doi : 10.1016/S0360-3016(21)00686-6
Volume 110, Issue 5, 1 August 2021, Pages A11-A12
The Evolving Personalized Landscape of Colorectal Cancer Therapies
Christopher J.AnkerMD*Michael H.BucksteinMD, PhD†Michael D.ChuongMD‡Maria A.HawkinsMD§JordanKharofaMD?Ann C.RaldowMD, MPH¶DianaTaitMD#Jeffrey R.OlsenMD??
doi : 10.1016/j.ijrobp.2021.03.016
Volume 110, Issue 5, 1 August 2021, Pages 1255-1262
Stereotactic Body Radiation Therapy for Patients With Sacral Chordoma Who Previously Received Carbon Ion Therapy
KeiItoMD, PhDHiroakiOgawaMD
doi : 10.1016/j.ijrobp.2018.11.029
Volume 110, Issue 5, 1 August 2021, Pages 1263-1264
Careful with the Cauda
Thomas F.DeLaneyMD
doi : 10.1016/j.ijrobp.2018.12.033
Volume 110, Issue 5, 1 August 2021, Page 1265
A Trial of Targeted Therapy
JulietteThariatMD, PhD
doi : 10.1016/j.ijrobp.2021.04.034
Volume 110, Issue 5, 1 August 2021, Pages 1265-1266
Mulling the Modalities
Kiran A.KumarMDRobert D.TimmermanMD
doi : 10.1016/j.ijrobp.2019.02.021
Volume 110, Issue 5, 1 August 2021, Page 1266
Missing Data in Clinical Studies
Amit K.ChowdhryMD, PhD?VinaiGondiMD†Stephanie L.PughPhD‡
doi : 10.1016/j.ijrobp.2021.02.042
Volume 110, Issue 5, 1 August 2021, Pages 1267-1271
Utility of Multi-institutional Pediatric Chart Rounds in the Age of Telemedicine
Christine H.FengMD*Steve E.BraunsteinMD, PhD†IainMacEwanMD*
doi : 10.1016/j.ijrobp.2021.03.036
Volume 110, Issue 5, 1 August 2021, Pages 1272-1273
Low-Dose Radiation Therapy for Severe COVID-19 Pneumonia: A Randomized Double-Blind Study
AlexandrosPapachristofilouMD?TobiasFinazziMD?AndreaBlumMD†TatjanaZehnderMD†N?riaZellweger†JensLustenbergerMD?TristanBauerMD?ChristianDott?YasarAvcu?G?tzKohlerPhD?FrankZimmermannMD?HansParggerMD†MartinSiegemundMD†
doi : 10.1016/j.ijrobp.2021.02.054
Volume 110, Issue 5, 1 August 2021, Pages 1274-1282
Low Doses of Radiation Increase the Immunosuppressive Profile of Lung Macrophages During Viral Infection and Pneumonia
LydiaMezianiPhD?†CharlotteRobertPhD?†‡MarionClasseMD, PhD?§BrunoDa CostaEng?MicheleMondiniPhD?†CélineClémensonPhD?†AlexiaAlfaroBEng¶PierreMordantMD, PhD#SamyAmmariMD, MSc??††RonanLe GofficPhD?EricDeutschMD, PhD?†‡
doi : 10.1016/j.ijrobp.2021.03.022
Volume 110, Issue 5, 1 August 2021, Pages 1283-1294
Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis
SarwatNazPhD*Andrew J.LeikerMD*†RajaniChoudhuriPhD*OliviaPrestonBA*Anastasia L.SowersAAS*SangeetaGohainMSc*JanetGamsonBS*AskaleMathiasMS*CarterVan WaesMD, PhD‡John A.CookPhD*James B.MitchellPhD*
doi : 10.1016/j.ijrobp.2021.03.048
Volume 110, Issue 5, 1 August 2021, Pages 1295-1305
Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Preclinical Models Enhances Single-Agent Immune Checkpoint Blockade
CaseyMooreBS?†Ching-ChengHsuPhD‡§Wei-MinChenPhD‡§Benjamin P.C.ChenPhD‡§ChuanhuiHanPhD†MichaelStoryPhD‡§ToddAguileraMD, PhD‡§Laurentiu M.PopMD‡RaquibulHannanMD, PhD‡§Yang-XinFuMD, PhD?†DebabrataSahaPhD‡§RobertTimmermanMD‡§?
doi : 10.1016/j.ijrobp.2021.03.047
Volume 110, Issue 5, 1 August 2021, Pages 1306-1316
The Oral CXCR4 Inhibitor X4-136 Improves Tumor Control and Reduces Toxicity in Cervical Cancer Treated With Radiation Therapy and Concurrent Chemotherapy
NazChaudaryPhD*Richard P.HillPhD*†‡§LukasStulikPhD?MichaelMilosevicMD*†§¶
doi : 10.1016/j.ijrobp.2021.03.031
Volume 110, Issue 5, 1 August 2021, Pages 1317-1324
Normal Tissue Injury Induced by Photon and Proton Therapies: Gaps and Opportunities
Pataje G.PrasannaPhD?KamilaRawojcPhD†ChandanGuhaMBBS, PhD‡Jeffrey C.BuchsbaumMD, PhD, FASTRO?Justyna U.MiszczykPhD§C. NormanColemanMD, FASTRO?
doi : 10.1016/j.ijrobp.2021.02.043
Volume 110, Issue 5, 1 August 2021, Pages 1325-1340
Caloric Restriction Impairs Regulatory T cells Within the Tumor Microenvironment After Radiation and Primes Effector T cells
GregorManukianMD, PhD?CharlesKivolowitzMS?TizianaDeAngelisMS?Anuradha A.ShastriPhD?Jason E.SavageMS†KevinCamphausenMD†UlrichRodeckMD‡Jelani C.ZarifPhD§Nicole L.SimoneMD?
doi : 10.1016/j.ijrobp.2021.02.029
Volume 110, Issue 5, 1 August 2021, Pages 1341-1349
The Importance of Radiation Dose to the Atherosclerotic Plaque in the Left Anterior Descending Coronary Artery for Radiation-Induced Cardiac Toxicity of Breast Cancer Patients?
Veerle A.B.van den BogaardMD, PhD?Daan S.SpoorMSc?Arjenvan der SchaafPhD?Lisanne V.van DijkPhD?EwoudSchuitPhD†Nanna M.SijtsemaPhD?Johannes A.LangendijkMD, PhD?John H.MaduroMD, PhD?Anne P.G.CrijnsMD, PhD?
doi : 10.1016/j.ijrobp.2021.03.004
Volume 110, Issue 5, 1 August 2021, Pages 1350-1359
The Effect of Bolus on Local Control for Patients Treated With Mastectomy and Radiation Therapy
AlanNicholMD?DylanNarinesinghMD?SrinivasRamanMASc, MD?FrancoisGermainMD†Elisa K.ChanMD?EricTranMD?LovedeepGondaraMS‡CarolineSpeersBA‡Caroline A.LohrischMD§PaulineTruongMD?
doi : 10.1016/j.ijrobp.2021.01.019
Volume 110, Issue 5, 1 August 2021, Pages 1360-1369
Postmastectomy Bolus: Urban Legend or Sound Practice?
Julie A.BradleyMD*Jonathan B.StraussMD†Jennifer R.BellonMD‡
doi : 10.1016/j.ijrobp.2021.04.024
Volume 110, Issue 5, 1 August 2021, Pages 1370-1372
ATM Variants in Breast Cancer: Implications for Breast Radiation Therapy Treatment Recommendations
Susan G.R.McDuffMD, PhD?Jennifer R.BellonMD†Kristen M.ShannonMS, LCGC‡Michele A.GaddMD§SamanthaDunnBS?Barry S.RosensteinPhD¶#Alice Y.HoMD?
doi : 10.1016/j.ijrobp.2021.01.045
Volume 110, Issue 5, 1 August 2021, Pages 1373-1382
Initial Results of a Phase 2 Trial of 18F-DOPA PET-Guided Dose-Escalated Radiation Therapy for Glioblastoma
Nadia NicoleLaackMD*DeannaPafundiPhD†S. KeithAndersonMS‡TimothyKaufmannMD§ValLoweMD§ChristopherHuntMD§DianeVogen*ElizabethYanMD?JannSarkariaMD?PaulBrownMD?SaniKizilbashMD*JoonUhmMD?MichaelRuffMD#MarkZakharyPhD¶YanZhangPhD**MaasaSeabergPhD?Hok SeumWan Chan TseungPhD*BrianKabatBS‡…DebraBrinkmannPhD?
doi : 10.1016/j.ijrobp.2021.03.032
Volume 110, Issue 5, 1 August 2021, Pages 1383-1395
Involved-Field Irradiation in Definitive Chemoradiotherapy for Locoregional Esophageal Squamous Cell Carcinoma: Results From the ESO-Shanghai 1 Trial
HongchengZhuMD, PhD?†EleonorRivin del CampoMD, PhD‡JinjunYeMD§Charles B.SimoneIIMD?ZhengfeiZhuMD?†WeixinZhaoMD?†AryaAminiMD¶JialiangZhouMD#ChaoyangWuMD??HuarongTangMD??MinFanMD?†LingLiMD, PhD?†QinLinMD††YiXiaMD‡‡YunhaiLiMD‡‡JianchengLiMD§§MiaoMoMS??¶¶HuixunJiaMPH##SaiquanLuMB?†JuanqiWangMS?†YongzhanNieMD???JunqiangChenMD§§ShixiuWuMD†††MasatsuguHamajiMD, PhD‡‡‡WaqarHaqueMD§§§Bae KwonJeongMD, PhD???RaviShridharMD, PhD¶¶¶ZhenZhangMD?†YunChenMD?†KuaileZhaoMD?†
doi : 10.1016/j.ijrobp.2021.02.053
Volume 110, Issue 5, 1 August 2021, Pages 1396-1406
Long-Term Outcomes of Radical Radiation Therapy with Hypoxia Modification with Biomarker Discovery for Stratification: 10-Year Update of the BCON (Bladder Carbogen Nicotinamide) Phase 3 Randomized Trial (ISRCTN45938399)
Yee PeiSongFRCR?†HiteshMistryPhD?‡JoelyIrlamPhD?HelenValentinePhD?LingjianYangPhD?BrianLanePhD?CatharineWestPhD?AnanyaChoudhuryPhD?†Peter J.HoskinFRCR?§
doi : 10.1016/j.ijrobp.2021.03.001
Volume 110, Issue 5, 1 August 2021, Pages 1407-1415
Enzalutamide With Radiation Therapy for Intermediate-Risk Prostate Cancer: A Phase 2 Study
IrvingKaplanMD?Glenn J.BubleyMD?Rupal S.BhattMD, PhD?Mary-EllenTaplinMD‡ShannaDowlingMPH?KathleenMahoneyMD, PhD?E.WernerMS†PaulNguyenMD§
doi : 10.1016/j.ijrobp.2021.02.027
Volume 110, Issue 5, 1 August 2021, Pages 1416-1422
A Multi-Institutional Analysis of Adjuvant Chemotherapy and Radiation Sequence in Women With Stage IIIC Endometrial Cancer
LaraHathoutMD?YaqunWangPhD?QingyangWang?IrinaVergalasovaPhD?Mohamed A.ElshaikhMD†IrinaDimitrovaMD‡ShariDamastMD§Jessie Y.LiMD§Emma C.FieldsMD?SushilBeriwalMD¶AndrewKellerMD¶Elizabeth A.KiddMD#MelissaUsoz#ShrutiJollyMD??ElizabethJaworskiMD??Eric W.LeungMD††ElysiaDonovanMD††Neil K.TaunkMD‡‡…Larissa J.LeeMD##
doi : 10.1016/j.ijrobp.2021.02.055
Volume 110, Issue 5, 1 August 2021, Pages 1423-1431
The Dynamic Alternation of Local and Systemic Tumor Immune Microenvironment During Concurrent Chemoradiotherapy of Cervical Cancer: A Prospective Clinical Trial
RuiLiMD*YuncongLiuMD, PhD†RutieYinMD‡LimeiYinMD*KeminLiMD‡ChuntangSunMD‡ZhipengZhouMD§PansongLiMD, PhD§RuizhanTongMD*JianxinXueMD, PhD*YouLuMD*
doi : 10.1016/j.ijrobp.2021.03.003
Volume 110, Issue 5, 1 August 2021, Pages 1432-1441
Prophylactic Cranial Irradiation Reduces Brain Metastases and Improves Overall Survival in High-Risk Metastatic Non-Small Cell Lung Cancer Patients: A Randomized phase 2 Study (PRoT-BM trial)
OscarArrietaMD, MSc?FedericoMaldonadoMD, MSc†Jenny G.TurcottPhD?Zyanya LuciaZatarain-Barr?nMD, MSc?FelicianoBarr?nMD, MSc?M?nikaBlake-CerdaMD†Luis AntonioCabrera-MirandaMD?Andrés F.CardonaMD, MSc, PhD‡§Jaime G.de la GarzaMD?RafaelRosellMD, PhD?
doi : 10.1016/j.ijrobp.2021.02.044
Volume 110, Issue 5, 1 August 2021, Pages 1442-1450
Multiblock Discriminant Analysis of Integrative 18F-FDG-PET/CT Radiomics for Predicting Circulating Tumor Cells in Early-Stage Non-small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy
Sang HoLeePhD?Gary D.KaoMD, PhD?Steven J.FeigenbergMD?Jay F.DorseyMD, PhD?Melissa A.FrickMD?SamuelJean-BaptisteMD?Chibueze Z.UchePhD?Keith A.CengelMD, PhD?William P.LevinMD?Abigail T.BermanMD, MSCE?CharuAggarwalMD, MPH†YongFanPhD‡YingXiaoPhD?
doi : 10.1016/j.ijrobp.2021.02.030
Volume 110, Issue 5, 1 August 2021, Pages 1451-1465
Benefits of Continuous Positive Airway Pressure (CPAP) During Radiation Therapy: A Prospective Trial
GaliaJacobsonMD?†Yaacov RichardLawrenceMRCP?†‡SaritAppelMD?†IlanaWeissMA*MaozBen AyunPhD*MeravAkiva Ben-DavidMD§?NirPeledMD, PhD¶Jeffrey D.GoldsteinMD*NoamWeizmanMSc#ShiraGalperMD?†OritKaidar-PersonMD?†??ZviSymonMD?†
doi : 10.1016/j.ijrobp.2021.03.044
Volume 110, Issue 5, 1 August 2021, Pages 1466-1472
This study aimed to study the impact of continuous positive airway pressure (CPAP) on chest anatomy and tumor motion in patients receiving radiation therapy.
Mean Heart Dose Is an Inadequate Surrogate for Left Anterior Descending Coronary Artery Dose and the Risk of Major Adverse Cardiac Events in Lung Cancer Radiation Therapy
Katelyn M.AtkinsMD, PhD*†Danielle S.BittermanMD†Tafadzwa L.ChaunzwaMD, MS†David E.KozonoMD, PhD†Elizabeth H.BaldiniMD, MPH†Hugo J.W.L.AertsPhD†‡Balaji K.TamarappooMD, PhD§UdoHoffmannMD||AnjuNohriaMD¶Raymond H.MakMD†
doi : 10.1016/j.ijrobp.2021.03.005
Volume 110, Issue 5, 1 August 2021, Pages 1473-1479
Proton Radiation Therapy for Pediatric Craniopharyngioma
Rachel B.JimenezMD?SohaAhmedMD†AndrewJohnsonBS?HoratioThomasMD‡NicolasDepauwPhD?NoraHorickMS§JoannaTanskyMD, PhD?Casey L.EvansPhD?MargaretPulsiferPhD?DavidEbbMD¶William E.ButlerMD#BarbaraFullertonPhD?Nancy J.TarbellMD?Torunn I.YockMD?Shannon M.MacDonaldMD?
doi : 10.1016/j.ijrobp.2021.02.045
Volume 110, Issue 5, 1 August 2021, Pages 1480-1487
Hearing Loss Risk in Pediatric Patients Treated with Cranial Irradiation and Cisplatin-Based Chemotherapy
SallyCohen-CutlerMD?KennethWongMD†‡VictoriaMenaAuD§KevinSiantoBS‡Michael A.WrightMD?ArthurOlchPhD†‡EtanOrgelMD, MS?†
doi : 10.1016/j.ijrobp.2021.02.050
Volume 110, Issue 5, 1 August 2021, Pages 1488-1495
Young Adult Populations Face Yet Another Barrier to Care With Insurers: Limited Access to Proton Therapy
Andrew J.BishopMD?J. AndrewLivingstonMD, MS†Matt S.NingMD?Isaac D.ValdezCMD?Cody A.WagesCMD?Mary FranMcAleerMD, PhD?Arnold C.PaulinoMD?David R.GrosshansMD, PhD?Kristina D.WoodhouseMD?RandaTaoMD‡Michael E.RothMD§G. BrandonGunnMD?Susan L.McGovernMD, PhD?
doi : 10.1016/j.ijrobp.2021.02.049
Volume 110, Issue 5, 1 August 2021, Pages 1496-1504
Young Adult Populations Face Yet Another Barrier to Care With Insurers: Limited Access to Proton Therapy
Thomas J.FitzGeraldMD
doi : 10.1016/j.ijrobp.2021.03.028
Volume 110, Issue 5, 1 August 2021, Pages 1505-1507
Deep Learning-Based Computed Tomography Perfusion Mapping (DL-CTPM) for Pulmonary CT-to-Perfusion Translation
GeRenMSc?JiangZhangMSc?TianLiPhD?HaonanXiaoMSc?Lai YinCheungMSc?†Wai YinHoMD†JingQinPhD‡JingCaiPhD?
doi : 10.1016/j.ijrobp.2021.02.032
Volume 110, Issue 5, 1 August 2021, Pages 1508-1518
Oxygen-Sensitive MRI: A Predictive Imaging Biomarker for Tumor Radiation Response?
Tatsuya J.AraiPhD*Donghan M.YangPhD*James W.CampbellIII*TsuichengChiuPhD†XinyiChengPhD†StrahinjaStojadinovicPhD†PeterPeschkePhD‡Ralph P.MasonPhD*
doi : 10.1016/j.ijrobp.2021.03.039
Volume 110, Issue 5, 1 August 2021, Pages 1519-1529
A Novel Analytical Population Tumor Control Probability Model Includes Cell Density and Volume Variations: Application to Canine Brain Tumor
StephanRadonicMSc*†JürgenBessererMSc*‡ValeriaMeierDVM*†Carla RohrerBleyDr.med.vet.‡UweSchneiderPhD*‡
doi : 10.1016/j.ijrobp.2021.03.021
Volume 110, Issue 5, 1 August 2021, Pages 1530-1537
Tumor control probability (TCP) models based on Poisson statistics characterize the distribution of surviving clonogens. Thus enabling the calculation of TCP for individuals. To mathematically describe clinically observed survival data of patient cohorts it is necessary to extend the Poisson TCP model. This is typically done by either incorporating variations of model parameters or by using an empirical logistic model. The purpose of this work is the development of an analytical population TCP model by mechanistic extension of the Possion model.
Insurer's Black Box: Inexplicable Barriers to Proton Therapy Access for Young Adults
Arpit M.ChhabraMDJ. IsabelleChoiMDShaakirHasanDORobert H.PressMDRafiKabarritiMDStanislavLazarevMDSuzanneWoldenMDCharles B.SimoneIIMD
doi : 10.1016/j.ijrobp.2021.04.006
Volume 110, Issue 5, 1 August 2021, Pages 1538-1539
In Regard to Shah and Royce
Einsley M.JanowskiMD, PhDKara D.RomanoMDTimothy N.ShowalterMD, MPH
doi : 10.1016/j.ijrobp.2021.04.044
Volume 110, Issue 5, 1 August 2021, Pages 1539-1540
In Regard to Brower et al
MuditChowdharyMDJohnShumwayMDTrevor J.RoyceMD, MS, MPH
doi : 10.1016/j.ijrobp.2021.04.043
Volume 110, Issue 5, 1 August 2021, Pages 1540-1541
In Reply to Schultheiss
VitaliMoiseenkoPhDJona A.Hattangadi-GluthMDMinh-PhuongHuynh-LeMDLawrence B.MarksMDJimmGrimmPhDMichael T.MilanoMD, PhDAndrewJacksonPhDEllenYorkePhDNiclasPetterssonPhDIssam ElNaqaPhD
doi : 10.1016/j.ijrobp.2021.03.019
Volume 110, Issue 5, 1 August 2021, Pages 1541-1543
In Regard to Nichol et al
AmishiBajajMDIndra J.DasPhD, FACR, FASTRO
doi : 10.1016/j.ijrobp.2021.03.024
Volume 110, Issue 5, 1 August 2021, Page 1543
In Reply to Bajaj and Das
AlanNicholMDDylanNarinesinghMDPaulineTruongMD
doi : 10.1016/j.ijrobp.2021.03.023
Volume 110, Issue 5, 1 August 2021, Pages 1543-1544
In Regard to Buchsbaum et al
JohnBrenemanMDJohn P.PerentesisMD, FAAPJeffreyBradleyMD, FACR, FASTROAnthonyMasciaPhD, DABREricAbelPhDAgamShardaMBADeepakKhuntiaMDRicky A.SharmaMA, MBBChir, FRCP, FRCR, PhDCharles B.SimoneIIMD, FACRO
doi : 10.1016/j.ijrobp.2021.03.034
Volume 110, Issue 5, 1 August 2021, Pages 1544-1545
In Reply to Breneman et al
Jeffrey C.BuchsbaumMD, PhD, AM, FASTROC. NormanColemanMD, FASTROJacekCapalaPhDCeferinoObcemeaPhD
doi : 10.1016/j.ijrobp.2021.03.033
Volume 110, Issue 5, 1 August 2021, Pages 1545-1546
In Regard to Deek et al
CemOnalMDOzan CemGulerMDEzgiOymakMD
doi : 10.1016/j.ijrobp.2021.04.004
Volume 110, Issue 5, 1 August 2021, Pages 1546-1547
In Reply to Onal et al
Matthew P.DeekMDBradley J.StishMDPhuoc T.TranMD, PhD
doi : 10.1016/j.ijrobp.2021.04.003
Volume 110, Issue 5, 1 August 2021, Pages 1547-1548
In Regard to Wages et al and Leite et al
ClaudioFiorinoPhDCesareCozzariniMDAndreiFodorMDNadia G.di MuzioMD
doi : 10.1016/j.ijrobp.2021.04.045
Volume 110, Issue 5, 1 August 2021, Pages 1548-1549
In Reply to Fiorino et al
Elton Trigo TeixeiraLeiteMDClarissa Cerchi AngottiRamosMDFabio YnoeMoraesMD
doi : 10.1016/j.ijrobp.2021.04.046
Volume 110, Issue 5, 1 August 2021, Pages 1549-1550
In Regard to Papachristofilou et al
Joseph J.BevelacquaPhDJames S.WelshMD, PhDS.M.J.MortazaviPhD
doi : 10.1016/j.ijrobp.2021.04.025
Volume 110, Issue 5, 1 August 2021, Pages 1550-1551
In Reply to Bevelacqua et al
TobiasFinazziMDAlexandrosPapachristofilouMDMartinSiegemundMD
doi : 10.1016/j.ijrobp.2021.04.026
Volume 110, Issue 5, 1 August 2021, Page 1551
Erratum to: DR, Owen; PS, Boonstra; BL, Viglianti; J, Balter; MJ, Schipper; W, Jackson; I El, Naqa; S, Jolly; R Ten, Haken; FM, Kong; MM, Matuszak. Modeling Patient-Specific Dose-Function Response Using Perfusion SPECT/CT for Enhanced Characterization of Personalized Functional Changes. Int J Radiat Oncol Biol Phys 2018;102(4):1265–1275.
doi : 10.1016/j.ijrobp.2021.04.011
Volume 110, Issue 5, 1 August 2021, Page 1552
