Radiotherapy and Oncology




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doi : 10.1016/S0167-8140(25)05343-5

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ESTRO recommendations on preoperative radiation therapy in breast cancer: current and future perspectives – Endorsed by ASTRO

doi : 10.1016/j.radonc.2025.111236

Volume 214, January 2026, 111236

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First online real-time motion-including prostate and bladder dose reconstruction during prostate radiotherapy

doi : 10.1016/j.radonc.2025.111298

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The climate and health impact of U.S. radiation therapy: estimating greenhouse gas emissions, DALYs, and potential of hypofractionation

doi : 10.1016/j.radonc.2025.111161

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Europe’s beating cancer plan: Opening avenues for radiation oncology

doi : 10.1016/j.radonc.2025.111259

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Sustainable innovation in addressing radiotherapy workforce challenges

doi : 10.1016/j.radonc.2025.111270

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ESTRO framework for radiation oncology departments to mitigate against cyberattacks

doi : 10.1016/j.radonc.2025.111305

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Unveiling regions associated with acute and late breast side-effects from breast radiotherapy using voxel-wise image-based data mining analysis

doi : 10.1016/j.radonc.2025.111230

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Comprehensive radiotherapy quality assurance analysis from individual DICOM data in the HypoG-01 phase 3 trial

doi : 10.1016/j.radonc.2025.111202

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Cardiac safety of ultra-hypofractionated whole breast irradiation: Results from the SAFE-FORWARD observational prospective cohort study

doi : 10.1016/j.radonc.2025.111267

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Survival outcomes and toxicity profile after CT-guided HDR brachytherapy (interventional radiotherapy) for liver oligometastases in breast cancer patients: The BRALIBREST real world multicenter study

doi : 10.1016/j.radonc.2025.111280

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Baseline characteristics predicting lower return rates of missing patient-reported quality of life data over 5 years: evidence from the IMPORT HIGH and IMPORT LOW breast cancer radiotherapy trials

doi : 10.1016/j.radonc.2025.111301

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Acute toxicity and quality of life after 5-fraction versus 15-fraction adjuvant radiotherapy following conventional or oncoplastic breast-conserving surgery − a real-world prospective cohort study

doi : 10.1016/j.radonc.2025.111310

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Relative biological effectiveness and neural stem cell fate in carbon ion–irradiated human brain organoids

doi : 10.1016/j.radonc.2025.111224

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Quantifying risk of radiation necrosis: Normal tissue complication probability modeling following stereotactic radiosurgery for small brain metastases in the modern era

doi : 10.1016/j.radonc.2025.111266

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Stereotactic radiotherapy on Parkinson’s disease induced tremors – a systematic review

doi : 10.1016/j.radonc.2025.111281

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Prognostic scores for patients with multiple brain metastases treated with repeated stereotactic radiosurgery − a secondary analysis of the CYBER-SPACE randomized phase 2 trial

doi : 10.1016/j.radonc.2025.111279

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A foundation model for brain tumor MRI analysis: WHO grading and subtype classification

doi : 10.1016/j.radonc.2025.111297

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Patterns of care in primary brain tumour Reirradiation: A survey by the ESTRO CNS focus Group

doi : 10.1016/j.radonc.2025.111299

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Evaluation of compartmentalized automatic segmentation for definition of the GTV in glioblastoma radiotherapy

doi : 10.1016/j.radonc.2025.111308

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Local therapy with hypoxia-targeting radiopharmaceutical [64Cu]Cu-ATSM in high-grade glioma patient-derived xenograft models

doi : 10.1016/j.radonc.2025.111325

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SHORT-COURSE RADIOTHERAPY FOR OLDER PATIENTS WITH LOCALLY ADVANCED RECTAL CANCER AND UNFIT FOR CHEMOTHERAPY: THE SOFT STUDY

doi : 10.1016/j.radonc.2025.111218

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Risk-based selection of treatment strategies in hepatocellular carcinoma with macrovascular invasion

doi : 10.1016/j.radonc.2025.111260

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Carbon ion therapy for pancreatic cancer with risk-adapted dose escalation: initial clinical experience

doi : 10.1016/j.radonc.2025.111238

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Novel rectal cancer spheroid models reveal metabolic and transcriptional adaptations driving radiotherapy response

doi : 10.1016/j.radonc.2025.111288

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Impact of treatment sequence and dose response on outcomes in locally advanced pancreatic cancer treated with hypofractionated proton beam therapy using simultaneous integrated boost technique

doi : 10.1016/j.radonc.2025.111295

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Integrating photon with proton dose–response data alters a pulmonary complication model-based patient selection in esophageal cancer

doi : 10.1016/j.radonc.2025.111289

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Quality of life and late toxicity after total neoadjuvant treatment for locally advanced rectal cancer – LARCT-US

doi : 10.1016/j.radonc.2025.111318

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An international placebo-controlled randomized multicenter trial of nimorazole with accelerated chemo-radiotherapy for locally advanced HPV-negative squamous cell carcinoma of the head and neck (HNSCC)

doi : 10.1016/j.radonc.2025.111227

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Risk of dysfunctional larynx after radiotherapy for early-stage glottic laryngeal cancer: A systematic review and meta-analysis

doi : 10.1016/j.radonc.2025.111226

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NPC-SurvAI: A fully automated deep learning framework for prognostic prediction and risk stratification in patients with nasopharyngeal carcinoma

doi : 10.1016/j.radonc.2025.111223

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Radiation dose inaccuracies near patient-specific osteosynthesis plates: an ex vivo dosimetric study

doi : 10.1016/j.radonc.2025.111244

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Brachytherapy (Interventional Radiotherapy) for lip carcinoma: excellent local control, low toxicity profile, and high patient satisfaction – The Dutch experience from four brachytherapy-dedicated head and neck cancer centers

doi : 10.1016/j.radonc.2025.111243

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Associations between patient-reported neurocognition, mood, and fatigue and radiation dose in oropharyngeal cancer survivors

doi : 10.1016/j.radonc.2025.111309

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Impact of dose and dose-averaged linear energy transfer on oro-pharyngeal-mucosal toxicity in patients with non-squamous head and neck cancers treated with carbon-ion radiotherapy

doi : 10.1016/j.radonc.2025.111314

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Patterns of lymphatic spread in hypopharyngeal squamous cell carcinoma – Findings from a multicenter study

doi : 10.1016/j.radonc.2025.111319

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International guidelines for the delineation of the postoperative clinical target volumes (CTV) for parotid and submandibular gland cancers

doi : 10.1016/j.radonc.2025.111317

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Clustering of dosimetric profiles reveals distinct local control probabilities after SABR in oligometastatic head and neck cancer: insights from the OMET phase II trial quality assurance Process

doi : 10.1016/j.radonc.2025.111316

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Patient selection for proton therapy in lung cancer: Nationwide external validation and model update of a prognostic model for 2-year mortality including mean heart dose

doi : 10.1016/j.radonc.2025.111257

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Long-term outcomes of concurrent chemo-proton therapy for unresectable stage III non-small cell lung cancer: a Japanese national registry study

doi : 10.1016/j.radonc.2025.111307

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Stereotactic ablative body radiotherapy for PSMA-PET/CT staged, oligometastatic prostate cancer – A multi-centre study

doi : 10.1016/j.radonc.2025.111219

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Urethra contours on MRI: Multidisciplinary consensus educational atlas and reference standard for artificial intelligence benchmarking

doi : 10.1016/j.radonc.2025.111231

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Quality assurance of contouring and dosimetric consistency in the GETUG-AFU 31 salvage prostate stereotactic reirradiation trial

doi : 10.1016/j.radonc.2025.111240

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Ultra-hypofractionated radiotherapy combined with HDR brachytherapy: An optimized treatment

doi : 10.1016/j.radonc.2025.111199

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Artificial intelligence-based lesion characterization and outcome prediction of prostate cancer on [18F]DCFPyL PSMA imaging

doi : 10.1016/j.radonc.2025.111265

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Improved metastasis-free survival without added toxicity in high- and very high-risk prostate Cancer: External beam radiotherapy alone versus in combination with HDR brachytherapy boost

doi : 10.1016/j.radonc.2025.111274

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Detection of local recurrent disease at biochemical failure after prostatectomy by multiparametric MRI versus PSMA PET/CT within a controlled study

doi : 10.1016/j.radonc.2025.111287

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Adjuvant radiotherapy in patients with pathological high-risk bladder cancer: Acute toxicity results from a randomized multicentre phase II trial (Bladder-ART/GETUG-AFU30)

doi : 10.1016/j.radonc.2025.111326

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Refining surveillance in Myxoid liposarcoma: long-term recurrence patterns and functional outcomes after surgery ± radiotherapy in 186 patients

doi : 10.1016/j.radonc.2025.111275

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Bridging radiotherapy for chimeric antigen receptor T cells therapy in non-Hodgkin lymphoma: Systematic review and meta-analysis

doi : 10.1016/j.radonc.2025.111258

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Pain control and opioid use as a function of workflow in MRI-guided interstitial cervix brachytherapy

doi : 10.1016/j.radonc.2025.111239

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Multicenter deep learning–based automatic delineation of CTV and PTV in uterine malignancy CT imaging

doi : 10.1016/j.radonc.2025.111212

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Diffusion weighted imaging for gross tumor volume delineation in primary radiochemotherapy and image guided adaptive brachytherapy for cervical cancer

doi : 10.1016/j.radonc.2025.111306

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Pain response of patients treated with radiotherapy for painful bone metastases between 2013 and 2024 – An analysis of the prospective real-world PRESENT cohort

doi : 10.1016/j.radonc.2025.111263

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Impact of target volume and dose concepts on the outcomes of prostate cancer patients treated with stereotactic body radiotherapy for spinal metastases − a European multicenter cohort study

doi : 10.1016/j.radonc.2025.111276

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Hypofractionated stereotactic body radiation therapy for metastatic epidural spinal cord Compression: A case series study

doi : 10.1016/j.radonc.2025.111320

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Course of quality of life in short- and long-term survivors after radiotherapy for bone metastases

doi : 10.1016/j.radonc.2025.111284

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A dedicated MKM-based radiobiological model for secondary cancer estimation in charged particle radiotherapy: An application in lymphomas and breast proton therapy

doi : 10.1016/j.radonc.2025.111229

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Model validation confirms variable relative biological effectiveness and elevated periventricular sensitivity after proton therapy of brain tumors

doi : 10.1016/j.radonc.2025.111271

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A pilot study evaluating 2D antiscatter grid based scatter suppression for quantitative cone beam CT in radiotherapy

doi : 10.1016/j.radonc.2025.111278

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Investigation of the combined role of dose and dose-averaged LET in the occurrence of brain necrosis after intensity modulated proton therapy for meningioma and solitary fibrous tumours

doi : 10.1016/j.radonc.2025.111290

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Assessing the potential and pitfalls of spot sequence optimization for OAR-specific dose rate control in proton PBS Bragg peak FLASH radiotherapy

doi : 10.1016/j.radonc.2025.111291

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Modality-AGnostic image Cascade (MAGIC) for multi-modality cardiac substructure segmentation

doi : 10.1016/j.radonc.2025.111296

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Online dose-adaptive radiotherapy considerably reduces irradiated volume in rectal cancer radiotherapy

doi : 10.1016/j.radonc.2025.111302

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A prospective study using a spirometry-based system on the positional reproducibility of anatomical landmarks and tumour-tracking accuracy

doi : 10.1016/j.radonc.2025.111315

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Dynamic prediction of Radiotherapy toxicities in Head and neck cancer using clinical and imaging data

doi : 10.1016/j.radonc.2025.111312

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A universal medical imaging modality translation model in brain and head-and-neck radiotherapy

doi : 10.1016/j.radonc.2025.111321

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Single-cell transcriptome sequencing reveals hepatocyte heterogeneity in response to radiation-induced liver injury and regeneration

doi : 10.1016/j.radonc.2025.111225

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Decrease in dose per fraction impairs the FLASH sparing effect in murine intestine model

doi : 10.1016/j.radonc.2025.111262

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Vascular dysfunctions during radiation retinopathy

doi : 10.1016/j.radonc.2025.111294

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Implementation of an automated contour quality assurance tool within the TROG 18.01 NINJA trial

doi : 10.1016/j.radonc.2025.111269

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Multicenter analysis of MRI-guided, stereotactic body radiotherapy as ablative treatment for lymph nodal metastases of the abdomen and pelvis

doi : 10.1016/j.radonc.2025.111237

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The concept of virtual clinical trials: A game changer in radiation oncology research?

doi : 10.1016/j.radonc.2025.111264

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International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases: A second update

doi : 10.1016/j.radonc.2025.111300

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ESTRO-ISRS clinical practice recommendations for re-irradiation of spinal metastases with Stereotactic Body Radiotherapy: Delphi consensus supported by a systematic review and meta-analysis

doi : 10.1016/j.radonc.2025.111304

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Dose-escalated stereotactic body radiotherapy re-irradiation in patients with recurrent head and neck cancer: a prospective phase 2 study using automated non-coplanar volumetric modulated arc therapy☆

doi : 10.1016/j.radonc.2025.111283

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Development of a treatment planning protocol for the multi-centre reirradiation CURE Lung trial☆

doi : 10.1016/j.radonc.2025.111293

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Cumulative dose evaluation in clinical reirradiation – Consensus guidance on technical considerations by the ESTRO reirradiation focus group☆

doi : 10.1016/j.radonc.2025.111313

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Cytosolic DNA in radiotherapy: relevance, mechanisms, and detection☆

doi : 10.1016/j.radonc.2025.111220

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Impact of oxygen deprivation on the FLASH effect for skin toxicity in a murine model☆

doi : 10.1016/j.radonc.2025.111277

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Systemic complement protein levels as biomarkers of chemoradiotherapy response in anal squamous cell carcinoma☆

doi : 10.1016/j.radonc.2025.111324

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Re-evaluating ‘Prospective evaluation of AI-based BiCycle autoplanning for advanced cervical cancer brachytherapy’: The silent cumulative CTVIR deficit

doi : 10.1016/j.radonc.2025.111216

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Response to letter to editor “Re-evaluating ‘Prospective evaluation of AI-based BiCycle autoplanning for advanced cervical cancer brachytherapy’: The silent cumulative CTVIR deficit�

doi : 10.1016/j.radonc.2025.111217

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Commentary on heterogeneity in nodal irradiation decisions: opportunities for refinement

doi : 10.1016/j.radonc.2025.111221

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Letter in Reply to: Heterogeneity in nodal irradiation decisions: opportunities for refinement

doi : 10.1016/j.radonc.2025.111222

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Personalizing brain metastasis radiotherapy with AI: can vision transformers bridge the gap?

doi : 10.1016/j.radonc.2025.111232

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Response to commentary on “Improving risk assessment of local failure in brain metastases patients using vision transformers − A multicentric development and validation study� by Zhang et al

doi : 10.1016/j.radonc.2025.111233

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Refining risk stratification in PSMA-PET guided salvage radiotherapy: methodological and translational considerations

doi : 10.1016/j.radonc.2025.111234

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Response to “Refining risk stratification in PSMA-PET guided salvage radiotherapy: methodological and translational considerations�

doi : 10.1016/j.radonc.2025.111235

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Peri-tumoral ring radiomics: vein-contaminated voxels inflate MFS scores

doi : 10.1016/j.radonc.2025.111272

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Response letter to the Commentary “Peri-Tumoral ring Radiomics: Vein-Contaminated Voxels Inflate MFS Scores�

doi : 10.1016/j.radonc.2025.111273

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Comment on “Quality assessment of 2705 treatment plans in the randomised Danish Breast Cancer Group Skagen trial 1�

doi : 10.1016/j.radonc.2025.111285

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Response to comment on “Quality assessment of 2705 treatment plans in the randomised Danish breast cancer Group Skagen trial 1�

doi : 10.1016/j.radonc.2025.111286

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Corrigendum to “Efficacy and safety of boron neutron capture therapy for Hypopharyngeal/Laryngeal cancer patients with previous head and neck irradiation�. [Radiother. Oncol. 198 (2024) 110382]

doi : 10.1016/j.radonc.2025.111228

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