Journal of Clinical Oncology




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KEYNOTE-585 Fails While Matterhorn Succeeds in Gastric Cancer: What Lessons Can We Learn?.

doi : 10.1200/JCO-25-01439

Volume 43(29) pgs. 3141-3231 October 10, 2025

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APOLLO: Optimizing the Treatment of High-Risk Acute Promyelocytic Leukemia With All-Trans Retinoic Acid and Arsenic Trioxide While Minimizing the Role of Chemotherapy.

doi : 10.1200/JCO-25-01496

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Brain Imaging Surveillance for Patients With Metastatic Breast Cancer: A Randomized Clinical Trial Is Required to Guide Practice.

doi : 10.1200/JCO-25-00356

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Pembrolizumab Plus Chemotherapy Versus Chemotherapy as Perioperative Therapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer: Final Analysis of the Randomized, Phase III KEYNOTE-585 Study.

doi : 10.1200/JCO-25-00486

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Arsenic Trioxide and All-Trans Retinoic Acid Combination Therapy for the Treatment of High-Risk Acute Promyelocytic Leukemia: Results From the APOLLO Trial.

doi : 10.1200/JCO-25-00535

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Randomized Phase II Trial of Pazopanib Versus Placebo in Patients With Advanced Extrapancreatic Neuroendocrine Tumors (Alliance A021202).

doi : 10.1200/JCO-24-02644

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Impact of Human Epidermal Growth Factor Receptor 2 in Patients With Metastatic Colorectal Cancer Treated With Chemotherapy Plus Bevacizumab or Anti-EGFRs: Exploratory Analysis of Eight Randomized Trials.

doi : 10.1200/JCO-25-01003

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Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor Exon 20 Insertion Mutations (WU-KONG1B).

doi : 10.1200/JCO-25-00788

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Xevinapant or Placebo Plus Platinum-Based Chemoradiotherapy in Unresected Locally Advanced Squamous Cell Carcinoma of the Head and Neck (TrilynX): A Randomized, Phase III Study.

doi : 10.1200/JCO-25-00272

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Second Mitochondrial Activator of Caspases Mimetics Accelerate Progression of Locally Advanced Head and Neck Cancer.

doi : 10.1200/JCO-25-01024

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Baseline Brain Metastasis Imbalance in TRUST: Implications for Interpreting Intracranial Efficacy of Taletrectinib.

doi : 10.1200/JCO-25-00967

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Taletrectinib in ROS1 Fusion-Positive Non-Small Cell Lung Cancer: Promising Yet Premature?.

doi : 10.1200/JCO-25-01055

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Reply to: "Baseline Brain Metastasis Imbalance in TRUST: Implications for Interpreting Intracranial Efficacy of Taletrectinib" and "Taletrectinib in ROS1 Fusion-Positive Non-Small Cell Lung Cancer: Promising Yet Premature?".

doi : 10.1200/JCO-25-01448

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Recalibrating Digital Predictions: Uncovering the Limits of the MMAI Prostate LT-ADT Predictive Model in the Era of Tumor Evolution.

doi : 10.1200/JCO-25-01213

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Reply to: Recalibrating Digital Predictions: Uncovering the Limits of the MMAI Prostate LT-ADT Predictive Model in the Era of Tumor Evolution.

doi : 10.1200/JCO-25-01303

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Erratum: TAR-200 for Bacillus Calmette-Guerin-Unresponsive High-Risk Non-Muscle-Invasive Bladder Cancer: Results From the Phase IIb SunRISe-1 Study.

doi : 10.1200/JCO-25-02053

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