Journal of Clinical Oncology




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Why Is Earlier Detection, the Key to Reducing Pancreatic Cancer, So Challenging Despite Technological Advances?.

doi : 10.1200/JCO-25-00796

Volume 43(26) pgs. 2843-2954 September 10, 2025

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Neoadjuvant Osimertinib: A Step Ahead or Just a Step?.

doi : 10.1200/JCO-25-01020

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Inconsistent and Inaccurate Cancer Clinical Trial Reporting of Venous and Arterial Thrombotic Events: An Urgent Call to Action.

doi : 10.1200/JCO-25-00489

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Long-Term Survival and Biomarker Analysis Evaluating Neoadjuvant Plus Adjuvant Relatlimab (anti-LAG3) and Nivolumab (anti-PD1) in Patients With Resectable Melanoma.

doi : 10.1200/JCO-25-00494

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Development and Validation of a Cell-Free DNA Fragmentomics-Based Model for Early Detection of Pancreatic Cancer.

doi : 10.1200/JCO.24.00287

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Neoadjuvant Osimertinib for Resectable EGFR-Mutated Non-Small Cell Lung Cancer.

doi : 10.1200/JCO-25-00883

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ADAGIO: A Phase IIb, Open-Label, Single-Arm, Multicenter Study Assessing the Efficacy and Safety of Adavosertib (AZD1775) as Treatment for Recurrent or Persistent Uterine Serous Carcinoma.

doi : 10.1200/JCO-24-01606

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Primary Analysis of EPIK-O/ENGOT-ov61: Alpelisib Plus Olaparib Versus Chemotherapy in Platinum-Resistant or Platinum-Refractory High-Grade Serous Ovarian Cancer Without BRCA Mutation.

doi : 10.1200/JCO-25-00225

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Dendrimer-Nanoparticle (DEP) Delivery of Topoisomerase I Inhibitor, SN38 (DEP-SN38): Safety, Tolerability, and Preliminary Efficacy Study in Patients With Advanced Solid Tumors.

doi : 10.1200/JCO-25-00236

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Diabetes and Colorectal Cancer Risk and Survival According to Tumor Immunity Status.

doi : 10.1200/JCO-25-00148

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US Food and Drug Administration Approval Summary: Trastuzumab Deruxtecan for the Treatment of Adult Patients With Hormone Receptor-Positive, Unresectable or Metastatic Human Epidermal Growth Factor Receptor 2-Low or Human Epidermal Growth Factor Receptor 2-Ultralow Breast Cancer.

doi : 10.1200/JCO-25-00812

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Caution Needed Before Adopting Reduced-Dose Elective Neck Irradiation in Head and Neck Cancer: A Response to UPGRADE-RT.

doi : 10.1200/JCO-25-00928

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Reply to: Caution Needed Before Adopting Reduced-Dose Elective Neck Irradiation in Head and Neck Cancer: A Response to UPGRADE-RT.

doi : 10.1200/JCO-25-01390

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